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      community GT20029 China Phase II Trial For AGA Reached Primary Endpoint

      in Research/Science  133 upvotes 2 years ago
      The GT20029 tincture, a topical androgen receptor degrader, showed significant hair growth and good safety in a China Phase II trial for male androgenetic alopecia (AGA), with the 1% dose twice weekly identified as optimal. The company plans to initiate Phase III trials in China and Phase II in the U.S., and the treatment also shows promise for acne.

      community Feeling the 2nd, perhaps 1st, Dutasteride shed, might shave, might thug it out.

      in Progress Pictures  67 upvotes 1 year ago
      The user is experiencing increased hair shedding after 6 months of using Dutasteride and oral minoxidil, despite previous regrowth and satisfaction with the results. They are considering shaving their head again and discuss the effectiveness of their treatment routine, which includes Dutasteride, oral minoxidil, and Nizoral, while also addressing concerns about side effects like erectile dysfunction and body composition changes.

      community Female on DHT blockers, need some advice.

      in Research/Science  4 upvotes 10 months ago
      A female experiencing hair loss while on testosterone replacement therapy is using oral Minoxidil, Spironolactone, and finasteride, but still losing hair. Suggestions include switching to dutasteride, using topical anti-androgens, and reducing Nizoral shampoo use to prevent scalp dryness.

      community any news about DUPA (Diffuse unpatterned alopecia)?

      in Research/Science  8 upvotes 3 years ago
      The conversation discusses diffuse unpatterned alopecia (DUPA) and its possible causes, including sensitivity to DHT, not being androgenic alopecia, being diffuse alopecia areata, or hormonal issues. Treatments mentioned include topical melatonin, Clobetasol Propionate for alopecia areata, and the lack of results from using finasteride, dutasteride, and minoxidil.

      community who else just can't seem to take finasteride?

      in Finasteride/Dutasteride  10 upvotes 1 year ago
      The user experienced severe side effects from finasteride, including anxiety and libido issues, and is currently using topical minoxidil and microneedling. They are considering trying dutasteride but are concerned about potential side effects.

      community applying tretinoin and SPF on scalp?

      in Treatment  1 upvotes 1 year ago
      The conversation discusses using tretinoin for hair loss and whether applying SPF on the scalp is necessary if hair covers the treated areas. The user is considering this treatment despite having no completely bald patches.

      community 27/M closing in on a year of fin and min, feel like it’s only gotten worse.

      in Chat  62 upvotes 2 years ago
      A user reported no improvement in hair loss after nearly a year of using 1mg oral finasteride, topical minoxidil twice daily, and weekly microneedling. Other users suggested the possibility of DUPA or retrograde alopecia and mentioned that treatments might only slow down hair loss rather than regrow hair.

      community Took the plunge, bros. 3500 grafts later..

      in Transplants  167 upvotes 11 months ago
      A user underwent a hair transplant with 3500 grafts after trying treatments like finasteride and minoxidil, preferring a local clinic in Toronto over traveling to Turkey. The user plans to continue using finasteride to maintain existing hair, as the transplanted hair is DHT resistant.

      community HT / Meds results are reverting, thinning, crazy shedding..

      in Progress Pictures  163 upvotes 1 year ago
      A user experienced significant hair shedding and thinning 10 months post-hair transplant despite using minoxidil and topical finasteride. They are considering switching to oral finasteride or dutasteride and are also dealing with scalp conditions like seborrheic dermatitis.

      community Dut is duting ig. 1 year progress.

      in Progress Pictures  427 upvotes 1 year ago
      The user has been using 5% minoxidil, finasteride, and dutasteride, along with microneedling and ketoconazole, to treat hair loss, showing significant progress over a year. Side effects mentioned include brain fog, watery semen, and facial dryness.

      community minoxidil and finasteride 3 months in

      in Progress Pictures  137 upvotes 1 year ago
      The user has been using topical minoxidil and oral finasteride for three months with visible hair thickening and no side effects. Another user mentioned experiencing watery semen and headaches with finasteride, and plans to add derma rolling and oils to their routine.

      community Having hair loss has completely changed the way I look at other men

      in Chat  99 upvotes 2 years ago
      A 22-year-old man shared his experience with hair loss, which began at age 20, and his treatment with finasteride and oral minoxidil, planning to add microneedling. Since experiencing hair loss, he has changed his perspective and now notices other men's hair loss more, viewing them positively, and others in the conversation relate to this shift in perception.

      community My experience with Pyrilutamide:

      in Research/Science  7 upvotes 3 years ago
      The user started using pyrilutamide for hair loss and experienced a significant reduction in hair shedding and an improvement in hair quality with only mild side effects. They previously used minoxidil and finasteride, which caused side effects, and are now combining pyrilutamide with minoxidil and tretinoin.

      community 7 months dutasteride minoxidil microneedling 25y.o. Some progress.

      in Progress Pictures  351 upvotes 1 year ago
      A 25-year-old shared progress in hair regrowth after 7 months using dutasteride, minoxidil, and microneedling, noting some baby hair growth on the temples. The user plans to continue this treatment, having found it effective despite some initial shedding and challenges with styling due to topical minoxidil.

      community The irony of balding while being hairy

      in Chat  107 upvotes 1 year ago
      The conversation discusses the frustration of having excessive body hair while experiencing scalp hair loss, with mentions of treatments like finasteride, minoxidil, and hair transplants using body hair. Users share experiences and advice, noting the role of genetics and DHT in hair growth patterns.

      community [M30] Constant swing between continuing or quitting Finasteride

      in General  204 upvotes 1 year ago
      A 30-year-old man is considering quitting Finasteride due to sexual side effects, including reduced libido and difficulty reaching orgasm, despite its effectiveness in treating hair loss. He is exploring other factors like relationship issues and potential low testosterone, and is considering getting blood work done.

      community Is this broscience? From More Plates, More Dates

      in Research/Science  21 upvotes 2 years ago
      The conversation discusses whether finasteride's reduction of DHT and increase in scalp testosterone contribute to hair follicle miniaturization. Some participants argue testosterone does not cause miniaturization, while others suggest that even with reduced DHT, other androgens like testosterone may still contribute to hair loss.