Search

everythinglearnresearchcommunity

for

Search:↓

GT20029 shows promise as a topical treatment for hair loss, potentially replacing finasteride for some due to its low systemic exposure and ability to degrade androgen receptors. However, skepticism remains about its long-term efficacy and availability, with some users expressing doubt about new treatments consistently failing to reach the market.

Hair loss treatments discussed include Minoxidil, Finasteride, RU58841, Alfatradiol, and Eucapil. Topical treatments must penetrate skin and may go systemic, with effectiveness varying.

A 23-year-old male is using 0.5 mg dutasteride daily, 5% minoxidil twice daily, and ketoconazole with zinc pyrithione shampoo twice a week to address diffused thinning and hair loss. He is seeking advice on whether his hair will regrow and if additional treatments are needed.

The conversation discusses the role of DHT in male hair loss and the effectiveness of treatments like Finasteride, which reduces DHT, and RU58841, which blocks DHT from binding to scalp receptors. The user debates the trade-offs between maintaining hair and having a healthy endocrine system, suggesting RU58841 might allow for both.

A 47-year-old male experienced significant hair regrowth over six months using 1mg oral finasteride, 5mg oral minoxidil, and 1ml 5% topical minoxidil, along with weekly derm stamping. He reported no major side effects, improved prostate health, and increased vascularity, with hair texture changes and minor nasal congestion.

Finasteride is effective for hair loss but can cause sexual dysfunction and mental health issues in some users, leading to a polarized debate on its risks. Some switch to alternatives like Dutasteride or topical treatments to avoid side effects.

A 25-year-old male experienced significant hair loss due to telogen effluvium and androgenetic alopecia. He began using finasteride, minoxidil, and vitamins, seeing some regrowth but remains worried about hair density.

Despite using dutasteride, RU58841, minoxidil, and ketoconazole for years, the user continues to experience severe hair loss and thinning. They seek advice after multiple dermatologists confirmed androgenetic alopecia (AGA) but offered no effective solutions.

A 22-year-old male shares his 2-month progress using a regimen of 0.5mg dutasteride daily, 1.5mm dermarolling weekly, a daily multivitamin, and a topical serum with 10% minoxidil and 0.1% finasteride. He reports impressive hair regrowth, especially at the hairline, and has experienced no sexual side effects.

The conversation discusses a transgender individual's successful hair loss treatment over 1.5 years using 2.5mg oral minoxidil, 5mg finasteride, and 8mg weekly injectable estradiol valerate. Some users debate the appropriateness of this approach within the group's goals, while others support the individualized treatment and its additional benefits for transgender individuals.

Managing estradiol levels while using finasteride. Treatments discussed include Minoxidil, finasteride, and RU58841.

The conversation is about using finasteride and testosterone replacement therapy (TRT) for hair loss and their role in gender-affirming care. It debates whether these treatments are considered hormone replacement therapy (HRT) and their implications for both cisgender and transgender individuals.

Ashwagandha may increase testosterone, which can convert to DHT and potentially affect hair loss, but using dutasteride should mitigate this concern. Users suggest that occasional Ashwagandha use is unlikely to impact hair loss significantly when on dutasteride.

Using topical finasteride with creatine might help reduce hair loss by targeting local DHT while maintaining normal systemic levels, but results are uncertain without testing. Users report mixed experiences with topical treatments like finasteride, dutasteride, RU58841, and minoxidil, with some seeing regrowth and others experiencing side effects.

Increased hair loss after starting a 10g daily creatine regimen, possibly linked to elevated DHT levels despite dutasteride use. Stopping creatine reduced shedding, but the exact cause is uncertain, with discussions on exercise and lifestyle impacts.

Finasteride use led to increased body hair and shedding, possibly due to Reflex Hyperandrogenicity. The user is considering trying Finasteride again and seeks advice on whether to proceed.

Finasteride is the most effective treatment for reducing DHT and addressing hair loss compared to fish oil and saw palmetto. Topical treatments like RU58841 and minoxidil are also discussed, but finasteride remains the most effective option.

A user is concerned about low testosterone while using finasteride 0.625mg MWF and considers ashwagandha for stress. Others suggest exercise, magnesium, and not worrying about testosterone levels if no significant side effects are felt.

Testosterone within the normal range does not significantly contribute to male pattern baldness (MPB); DHT is the main factor that can be controlled. Genetics play a crucial role in hair loss, and treatments like finasteride and dutasteride, which block DHT, can help despite potentially raising testosterone levels.

Stemoxydine's effects on hair growth are uncertain and not well-studied, with users reporting mixed results and concerns about maintaining gains. Some users combine it with 5AR inhibitors like Dutasteride, but results vary, and conditions like lichen planopilaris complicate treatment.

A 27-year-old male experiencing hair loss at Norwood 3 level has tried minoxidil and finasteride but stopped finasteride due to side effects. He is exploring alternatives like Dermapen, Regenepure DR Shampoo, saw palmetto, and considering aromatase inhibitors for managing side effects, while also seeking advice on DHT blockers.

A user reported a significant reduction in DHT levels after 3 months of taking 1mg/day oral finasteride, along with using minoxidil foam, microneedling, and Nutrafol vitamins. They hope this will lead to hair growth and less shedding.

A 20-year-old is experiencing hair thinning and is considering Clascoterone and Minoxidil as treatments, avoiding finasteride due to concerns about fertility and hormones. A suggestion was made to use Clascoterone for local DHT targeting and combine it with Minoxidil for maintenance and regrowth while avoiding systemic side effects.

The "DHT itch" is real and likely due to inflammation at the hair follicle, exacerbated by increased testosterone or androgens. Treatments mentioned include dutasteride, minoxidil, finasteride, and various topical solutions.

Grapefruit juice doesn't significantly affect finasteride or dutasteride. Drinking topical minoxidil is risky; saw palmetto is less effective than finasteride or dutasteride for hair loss.

A 32-year-old male experienced reduced libido and erectile difficulties after taking Minoxidil and Dutasteride for hair loss. He stopped the treatment and plans to consult his doctor, seeking similar experiences from others.

A user discusses dealing with lower libido caused by finasteride, considering using ED meds but unsure due to age. Replies suggest natural libido fluctuations, holistic approaches, and managing anxiety.

The user is considering switching from oral to topical dutasteride and minoxidil due to concerns about mental health effects from lower DHT levels. They are seeking advice on the effectiveness and side effects of this change, including potential hair shedding and density changes.

A trans woman is experiencing hair loss and is considering treatments like cyproterone, dutasteride, and oral minoxidil. She is concerned about potential hair growth on her face, chest, or legs due to minoxidil.

A 27-year-old male physician improved hair density using minoxidil 5% foam and finasteride 1mg every other day, with initial sexual side effects that subsided. He recommends trying finasteride for a year but warns against dutasteride due to potential liver effects.