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      community Pyrilutamide ,the molecule’s true nature

      in Research  302 upvotes 1 year ago
      Pyrilutamide is a selective AR antagonist with a high binding affinity, making it effective in competing with DHT for androgen receptors. The 1% concentration is more effective than the 0.5%, but the latter may suffice for mild hair loss; the drug is considered a good option for those avoiding 5AR blockers due to side effects.

      community 6 Months Oral Dut/Min Progress

      in Progress Pictures  80 upvotes 5 months ago
      A 23-year-old male experienced significant hair regrowth and increased libido after switching from oral finasteride to 0.5 mg oral dutasteride and 2.5 mg oral minoxidil, following hair loss induced by a testosterone cycle. He reported initial shedding and decreased libido with finasteride, but no side effects with dutasteride, and noted improvements in hair density, temple regrowth, and reduced acne.

      community For people with overly oily hair, does topical finasteride/dutasteride/antiandrogens (like RU or Pyrilutamide) reduce sebum overproduction?

      in Finasteride/Dutasteride  6 upvotes 2 years ago
      The conversation discusses whether topical finasteride, dutasteride, or antiandrogens like RU58841 can reduce sebum overproduction as an early indicator of their effectiveness in treating hair loss. It suggests that while hair growth may take months to observe, a decrease in oiliness could be a quicker sign of a product's action.

      community Gains or growth? Three months in

      in Is this regrowth?  146 upvotes 1 year ago
      The user is using topical minoxidil twice daily for hair regrowth and is hesitant to use finasteride due to concerns about hormonal effects. The conversation includes mixed opinions on the effectiveness of the treatment and suggestions to use a DHT blocker for better results.

      community Patent for topical resveratrol and melatonin for AGA

       6 upvotes 6 years ago
      The conversation discusses a patent for using topical resveratrol and melatonin to treat androgenetic alopecia (AGA) and also mentions interest in topical sulforaphane as a treatment.

      community Beyond Minoxidil & Finasteride: What if the Answer to Male Pattern Baldness is... on Our Faces? (A Naval Officer's Wild Idea & Why It's Not So Crazy)

      in What should I do? 6 months ago
      Exploring the idea of using facial hair properties for scalp regeneration in male pattern baldness, considering the potential of transferring androgen-resistant characteristics from facial hair to the scalp. Challenges include complexity, scalability, aesthetics, and safety, but the concept encourages innovative thinking beyond current treatments like Minoxidil, Finasteride, and hair transplants.

      community Tribulus Terrestris and Zinc to boost libido on fin

      in Finasteride/Dutasteride  3 upvotes 4 years ago
      The conversation discusses using Tribulus Terrestris and Zinc to boost libido while on finasteride, with some users reporting success in increasing libido despite no testosterone boost. The original poster also considers reducing finasteride dosage and using Cialis for libido and bodybuilding purposes.

      community Am I losing my mind or should I be concerned

      in General  144 upvotes 10 months ago
      The user switched from topical to oral finasteride and minoxidil for hair loss and experienced swelling and sensitivity in the left chest area. They are concerned about these symptoms but noticed improvement after skipping a dose.

      community Supplementation increasing T levels

      in Treatment  4 upvotes 4 years ago
      The conversation is about using finasteride for hair loss and considering supplements like ginseng or ashwagandha to boost testosterone levels. Concerns are raised about potential negative effects on hair due to increased DHT conversion, and it's suggested that natural testosterone boosters may not significantly impact those with already high testosterone levels.

      community Is Finasteride the only way to reduce scalp DHT?

      in Chat  28 upvotes 5 months ago
      A 24-year-old male experienced side effects like low libido and ED after starting finasteride post-hair transplant and is seeking alternatives to reduce scalp DHT. Suggestions include topical finasteride, Xpecia, DHT-reducing shampoos, and switching to dutasteride, with some users reporting fewer side effects with these alternatives.

      community Dutasteride vs Finasteride and Steroid

      in Progress Pictures  87 upvotes 6 months ago
      Dutasteride is preferred over finasteride for hair loss due to fewer side effects. Combining dutasteride with minoxidil and RU58841 is effective for hair regrowth, even during steroid use.

      community I (diffuse thinner) would genuinely prefer having the Generic MPB hairloss

      in Chat  35 upvotes 1 year ago
      The conversation discusses struggles with diffuse thinning and hair loss treatments, including the use of dutasteride, minoxidil, and finasteride, with limited success. The original poster regrets having a hair transplant at 21 due to weak donor hair and ongoing thinning.

      community any news about DUPA (Diffuse unpatterned alopecia)?

      in Research/Science  11 upvotes 3 years ago
      The conversation discusses diffuse unpatterned alopecia (DUPA) and its possible causes, including sensitivity to DHT, not being androgenic alopecia, being diffuse alopecia areata, or hormonal issues. Treatments mentioned include topical melatonin, Clobetasol Propionate for alopecia areata, and the lack of results from using finasteride, dutasteride, and minoxidil.

      community Testosterone and hair loss seeming irrelevance

      in Research/Science  80 upvotes 2 years ago
      The conversation is about the role of testosterone in hair loss and the effectiveness of different treatments. The conclusion is that DHT is the main culprit for hair loss, and finasteride has been proven to work long-term in maintaining and regrowing hair. Testosterone may have a minor effect, but it is not the primary cause of hair loss.

      community 4 months of AGA therapy Finasterdie 1,25 EOD and Regaine

      in Progress Pictures  83 upvotes 1 month ago
      A 30-year-old with Norwood 3V hair loss uses finasteride 1.25 mg every other day and Minoxidil (Regaine 5%) twice daily, experiencing no side effects with the current regimen. The front hairline remains unchanged, but the crown appears better in certain lighting.

      community Bloodwork after 8 months on finasteride, is this normal?

      in Update  28 upvotes 2 years ago
      A user on finasteride for 8 months shared bloodwork results showing increased testosterone and estradiol levels, with concerns about high LH. Responses advised monitoring for symptoms but noted levels are within reference ranges.

      community Ru-58841 vs KX-826/pyrilutamide while on steroids

      in Finasteride/Dutasteride  4 upvotes 1 year ago
      The user increased their steroid dosage and noticed hair shedding, so they adjusted their regimen by reducing steroid doses and adding oral dutasteride. They are also experimenting with combining RU-58841 and KX-826/pyrilutamide in minoxidil to address hair loss.

      community Bloodwork after 17 months on finasteride

      in Finasteride/Dutasteride  1 upvotes 1 year ago
      A 25-year-old male has been using finasteride for 17 months and recently switched to dutasteride. His bloodwork shows increased luteinizing hormone levels, possibly due to increased testosterone, with no side effects and improved libido.

      community concerns about starting minoxidil

      in Female  1 upvotes 4 years ago
      An 18-year-old woman experiencing hair loss due to stress, possible PCOS, and low vitamin D is concerned about starting 5% minoxidil foam, prescribed by her doctor, due to potential facial hair growth. She is also using a topical steroid for scalp sensitivity and pain.