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      community Topical is superior to oral in terms of results (my theory)

      in Finasteride/Dutasteride  61 upvotes 2 years ago
      The conversation discusses the use of topical minoxidil and finasteride for hair loss, with some users combining them with oral treatments. Users share their experiences and opinions on effectiveness, cost, and convenience, with mixed views on whether topical or oral applications are superior.

      community Is it possible to have low scalp vascularity??

      in Treatment  3 upvotes 2 years ago
      The user is using topical dutasteride, finasteride, minoxidil, and tretinoin but seeing no results or side effects. They also microneedle every two weeks but experience little bleeding, questioning if a thick scalp is preventing treatment effectiveness.

      community Question about topical part of treatment

      in Treatment  2 upvotes 2 years ago
      The user is using a combination of oral Dutasteride and Minoxidil, and a topical formula with Finasteride, Minoxidil, and Hydrocortisone, along with rosemary oil, coconut oil, ginseng, and a derma roller. They are also using LLLT therapy and are questioning the timing of the laser cap session in relation to the topical application.

      community Six month topical min/fin check-in.

      in Is this regrowth?  270 upvotes 1 year ago
      The user is pleased with increased hair density and thickness after six months of using topical minoxidil and finasteride. They plan to continue the treatment and consider adding dermarolling for potentially better results.

      community Update and new paper from Dr tsuji

      in Update  25 upvotes 7 years ago
      Hair follicle regenerative therapy is being developed, with clinical trials planned in Japan, potentially allowing for hair cloning and eliminating the need for treatments like finasteride. If successful, the treatment could be available in Japan by 2025, but widespread access and affordability may take longer.

      community Seen Alfatradiol mentioned on here a few times recently and found this study - in case anybody is interested. Translated from German.

      in Treatment  4 upvotes 4 years ago
      Alfatradiol (0.025%) is an effective and safe treatment for androgenetic alopecia in both men and women, increasing anagen hair rates with minimal side effects. Users discuss its cost-effectiveness and ease of use compared to other treatments like finasteride and RU58841, with some combining it with stemoxydine and Minoxidil.

      community high estrogen levels after 10month fin

      in Finasteride/Dutasteride  9 upvotes 2 years ago
      A user experienced high estrogen levels after 10 months of taking 1mg oral finasteride but is happy with hair regrowth. They are considering switching to topical finasteride and are also taking DIM and Zinc supplements.

      community 3 year fin/min progress (age 27-age 30)

      in Progress Pictures  1013 upvotes 1 year ago
      A user shared their 3-year progress using 1mg finasteride and 5% topical minoxidil twice daily, reporting significant hair regrowth and some side effects like bloating, seborrheic dermatitis, and water retention. The user is happy with the results, noting improvements in both the crown and hairline.

      community Ru58841 after a hair transplant

      in Transplants  7 upvotes 1 year ago
      A user discussed their hair transplant progress and mentioned using 1mg Finasteride, 5% Topical Minoxidil, and recently starting 5% RU58841. They are seeking advice on whether to use RU58841 at month 4 post-transplant.

      community NW5 at 19. How many grafts do I need?

      in Transplants  138 upvotes 2 years ago
      A 19-year-old with rapid hair loss since 16 is considering a hair transplant but refuses to take finasteride or any 5α-Reductase inhibitors. They are currently using minoxidil, tretinoin, and microneedling with a Derminator 2, and only want hair until age 27.

      community 85 days Topical Min-Fin progress

      in Is this regrowth?  10 upvotes 8 months ago
      The user has been using a treatment of 0.1% topical finasteride, 5% minoxidil, dermastamping, and vitamin D3 supplements for 85 days and is seeing good progress. Other users note the effectiveness of topical finasteride despite it being less potent.
      FCE 28260: A Forgotten 5α-Reductase Inhibitor

      community FCE 28260: A Forgotten 5α-Reductase Inhibitor

      in Research  330 upvotes 1 year ago
      FCE 28260 (PNU 156765), an under-explored 5α-reductase inhibitor, showcases promising results in research by Giudici et al., outperforming well-known treatments like Finasteride in reducing the conversion of testosterone to DHT. Its superior efficacy, demonstrated through lower IC50 values in both natural and human recombinant enzyme studies, suggests it could offer more effective management of DHT-related conditions. Additionally, its lower molecular weight hints at better potential for topical application, potentially offering advantages in treating conditions such as androgenic alopecia. Despite its potential, it has not advanced in development, possibly due to financial limitations, leaving its therapeutic prospects and side effect profile largely unexplored.

      community Starting Pyrilutamide BID. First dose was yesterday. Diffuse thinning. I will put my full regimen below.

      in Research/Science  89 upvotes 3 years ago
      A user's regimen to help with their diffuse thinning, which includes taking Pyrilutamide BID, 1mg finasteride daily, 2.5mg oral minoxidil daily, topical minoxidil since August 2021, LLLT every two days, topical fin, progesterone, melatonin, minoxidil (started one week ago), pumpkin seed oil and not dermarolling; other commenters suggested Nizoral for dandruff control and caution when using pre-mixed products with Pyrilutamide.

      community 7 months update - 1 mg fin, topical min

      in Progress Pictures  736 upvotes 3 years ago
      A user's 7-month progress using 1 mg finasteride and topical minoxidil, with no side effects from the finasteride, achieving baby hairs on the hairline and other positive results. Other users have discussed different treatments such as microneedling and supplements, providing advice and encouragement to the poster.

      community Fin+Colostrum: My journey is a little different.

      in Is this regrowth?  14 upvotes 1 year ago
      The user has been using finasteride for 30 years and recently added colostrum to their routine, noticing darker hair regrowth. They experienced shedding with minoxidil and advise against its use, while highlighting the benefits and side effects of long-term finasteride use.

      community 5 months progress on fin and min

      in Progress Pictures  1831 upvotes 1 year ago
      Significant hair regrowth was achieved using oral finasteride and topical minoxidil over five months, with noticeable improvements in hairline and temple areas. The user experienced minimal side effects, mainly increased eyebrow and eyelash growth, and attributes additional physical improvements to weight loss and exercise.