A user used dutasteride 0.5mg for 3 months and is unsure about hair regrowth, noting some greying. Responses suggest improvement and that full regrowth may take time with shedding cycles.
Fluridil degrades androgen receptors, which are prevalent in the scalp and other tissues. People with androgenetic alopecia (AGA) may have higher expression of these receptors and 5AR activity in affected scalp areas.
A 19-year-old male experienced hair shedding after one year on dutasteride and is considering adding topical minoxidil despite scalp itching. Users suggest continuing dutasteride, maintaining a consistent hair routine, and possibly increasing minoxidil dosage.
The conversation discusses whether a longtime NW7 scalp has vellus hairs under a microscope or is completely smooth. Treatments mentioned include Minoxidil, finasteride, and RU58841.
The conversation is about making a solution of RU58841 using propanediol instead of propylene glycol due to skin irritation. The user seeks advice on whether this substitution is acceptable.
A user switched from RU58841 to Pyrilutamide for hair loss treatment after experiencing side effects and continued hair shedding with RU. They are now losing hair faster with Pyrilutamide and questioning if they should revert to RU58841.
OP shared progress pictures after 7 months of using a topical solution with 0.25% finasteride and 5% minoxidil, prescribed by a dermatologist. OP experienced mild shedding initially and noticed significant growth by the third month.
The user experienced continued hair loss and scalp itch despite using finasteride and switching to dutasteride. They sought advice on managing these issues, with suggestions including adjusting medication frequency and trying different shampoos.
User used sublingual minoxidil for 5 months and saw progress. Also used topical dutasteride, alfatradiol, tretinoin, and reduced oral finasteride dose.
User experienced hair regrowth after eliminating scalp itch with RU58841. Others discussed itch and hair loss connection, and effectiveness of combining RU58841 with 5AR inhibitors.
The user experienced increased shedding and side effects like oily skin and acne after switching from finasteride to dutasteride, despite initially having success with finasteride. They also tried oral spironolactone, which reduced libido but didn't help with hair loss, and are considering returning to finasteride only.
User starts Nuclear Stack treatment for hair loss, including Dutasteride, Minoxidil, RU58841, Derminator 2, and supplements. Seeks advice on storing and dosing RU58841.
The conversation discusses the duration of hair shedding caused by RU58841. The user is stressed and seeking information on how long the shedding phase lasts.
The user is experiencing increased hair shedding and is concerned about regression despite consistent use of finasteride, minoxidil, and other treatments. The consensus is that this is likely a temporary shedding phase, and adjustments to the dermarolling frequency are suggested.
The conversation is about a user experiencing hair shedding after switching from finasteride to dutasteride and increasing their oral minoxidil dose. The user is advised to continue with the current treatment, consider adding topical minoxidil, and consult a dermatologist for potential underlying issues.
The user experienced another hair shed and plateau at month 5 using 6% minoxidil and 0.3% finasteride, with an itchy scalp indicating potential regrowth. They find the topical spray easy to use and saw results within two months, but caution that stopping use may lead to hair loss.
The post discusses a hair loss treatment regimen including oral finasteride, topical minoxidil, a rejuvenating scalp serum with caffeine, rosemary, and ginger, topical ketoconazole, saw palmetto, and derma rolling. The user seeks advice for scalp pimples and irritation.
A 28-year-old male has been using topical dutasteride and minoxidil for a year without improvement, experiencing persistent hair shedding. It is suggested that the treatment might not be effective for him, and he should consider other approaches or check for underlying conditions.
A woman experiencing hormonal hair loss is on dutasteride and bicalutamide, which initially improved her hair, but she is now experiencing a second shedding phase with significant short hair loss. Despite normal hormone levels and no deficiencies, she is unsure if this shedding is normal and seeks advice.
The user is experiencing hair regrowth after using 0.5mg dutasteride daily, 8% topical minoxidil twice daily, 2.5mg oral minoxidil daily, a 1.5mm derma stamp weekly, and keto shampoo 2-3 times weekly for two months. The progress is considered good, though there is a concern about scalp inflammation.
The user is struggling with seborrheic dermatitis and plans to try ciclopirox olamine after finding ketoconazole too drying. They are also using finasteride daily.
Mixing Nizoral and T-Gel in a 1:1 ratio and using it three times a week provided relief from persistent seborrheic dermatitis. This treatment is recommended for those with stubborn SD.
A user shared 3 months of progress using daily Dutasteride 0.5mg and Minoxidil 5mg, with Dutasteride mesotherapy every 4 months. They prefer not to use additional treatments for now.
A 22-year-old male uses dutasteride, a serum with 10% minoxidil and 0.5% finasteride, and microneedling for diffuse androgenetic alopecia. Progress pictures show changes from July 2025 to February 2026.
Dutasteride can cause prolonged hair shedding before regrowth begins, often taking 6-12 months for noticeable improvement. Users report varying experiences, with some seeing no shedding and others experiencing significant shedding before eventual regrowth.
A person has been using finasteride, minoxidil, OM, dutasteride, and RU58841 for hair loss for various durations but is still experiencing constant shedding and thinning. Suggestions from others include checking for potential nutritional deficiencies.
DLQ01, a prostaglandin F2α analog, shows promise for hair growth by directly stimulating PGE2/PGF receptors without needing conversion, and can be combined with minoxidil and retinoids like tretinoin for enhanced effectiveness. Minoxidil's efficacy may be reduced by COX-1 inhibitors, but using prostaglandin analogs like Latanoprost or Bimatoprost can help maintain its effectiveness.
After 2 years of using finasteride and minoxidil with good results, the user is experiencing severe scalp itchiness, shedding, and tenderness. Despite dermatologists finding nothing wrong, the user seeks over-the-counter treatments for the itch.
PP405 shows promise in regenerating hair by activating dormant follicles. Other treatments like VDPHL01 and Breezula are also advancing, providing new hope for hair loss solutions.
Switching from liquid to foam minoxidil led to hair loss for OP, possibly due to a second shedding cycle. OP experienced allergic reactions to propylene glycol in the liquid form, causing dandruff and itchiness, which improved after switching to foam.