community PP405 Won't Work Long Term: Hair Follicle Damage Due to Abuse of the ISR System
PP405 may damage hair follicles if used long-term, suggesting cycling might be necessary. Combining it with finasteride could help maintain hair growth.
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30 / 1000+ resultscommunity PP405: The Ultimate Hair Loss Drug for Complete Hair Growth
PP405 is a new hair loss treatment in phase 2 trials that may promote hair growth by increasing lactate production and activating hair follicle stem cells. It could potentially replace hormone-disrupting treatments like Minoxidil and finasteride.
community CRISPR Is Curing People Right Now. Genetic Hair Loss is Next?
CRISPR shows promise for treating hair loss by targeting specific genes. Current treatments include Minoxidil and finasteride, but CRISPR could offer a more precise solution, though it is still expensive and in early stages.
community It's always the Mice that gets to grow back hair.
Sodium dodecyl sulfate, oleic acid, and palmitoleic acid may promote hair growth, but their safety and effectiveness for humans are uncertain. Users consider trying these treatments cautiously, exploring alternatives like ostrich oil and microneedling.
community The case of a 78 year old man who accidentally regrew his hair (published in the British Medical Journal)
A 78-year-old man regrew hair after suffering burns, suggesting that injury-induced healing processes might trigger hair growth. Microneedling and other treatments like minoxidil and finasteride are discussed as potential methods to stimulate similar regrowth.
community It works. About a 1 year transformation.
A user's experience with hair loss treatments, specifically Minoxidil and finasteride, which they have used without side effects for a year. Other users shared their experiences and advice about potential side effects and supplements to help.
community Someone here experience with/or knows stories of cancer-patience regrowing hair?
Hair regrowth after chemotherapy varies; some experience thinner or differently colored hair, while others may see fuller regrowth. Treatments like essential oils, vitamins, and lifestyle changes are discussed, but no specific medications like Minoxidil or Finasteride were used by the original poster.
community When you start balding you notice how unnatural this phenomenon is
Hair loss is a common issue, with treatments like finasteride and minoxidil used but not as permanent cures. Frustration exists over societal perceptions and the lack of a definitive solution.
community ~3 years on fin and alpecin shampoo
The user has been using finasteride and Alpecin shampoo for about three years, reporting thicker hair but an unchanged hairline. They are happy with their hair progress, noting the most improvement in the past five months, and mention a slight decrease in libido.
community There’s a war against finasteride and dht blockers
Finasteride is a controversial hair loss treatment, with some users experiencing positive results and others facing side effects like erectile dysfunction. The discussion emphasizes the importance of personal choice and informed decision-making.
community How far are we from gene editing stem cells and implanting them?
Gene editing for hair loss is not yet viable due to technological and economic challenges. Current treatments like Minoxidil, finasteride, and hair transplants remain the most practical options.
community Story time! The Great Unbalding (PP405)
PP405 is a promising new hair loss treatment that may reactivate dormant hair follicles without side effects. It could surpass traditional treatments like minoxidil and finasteride if successful in further trials.
community Would you trade your ability to grow beard with head full of hair?
Many would trade beard growth for a full head of hair, using treatments like minoxidil and finasteride. Some prefer beards or have experienced side effects, leading to mixed opinions.
community 2 years on treatment (stack update)
A user shared their hair regrowth progress using Dutasteride, topical Minoxidil, Spironolactone, and Estradiol Valerate injections as part of hormone replacement therapy for transitioning. They experienced significant hair improvement and personal satisfaction but caution against this approach for non-transitioning individuals due to irreversible changes.
community Confused why people are calling PP405 a cure...it never claimed to be able to undo miniaturization or revert vellus back to terminal hairs. It seems to be more of a growth stimulant like minoxidil.
PP405 is not a cure for hair loss but may reactivate dormant hair follicles, similar to minoxidil. It is unlikely to help with miniaturized or vellus hairs and is still in trial phases, with availability expected around 2030.
community Wouldn’t it be funny if there already was a drug that existed which reactivated sleeping follicles? It would be our own version of Ozempic
PP405 shows promise for reactivating hair follicles, with potential maintenance using 5AR inhibitors. Current treatments like Minoxidil and finasteride are effective but have limitations, and there is hope for more effective solutions in the future.
community 22 | ~34 Months Finasteride Update
A user shared their 34-month update on using finasteride for hair loss, noting they maintained regrowth even after stopping minoxidil a year ago. Other users shared similar experiences and expressed admiration for the results.
community I’m gutted and this is my last post on this thread
User tried various hair loss treatments without success and plans to consult a dermatologist and possibly shave head for emotional well-being.
community Are permanent hair gains even possible?
Hair regrowth from treatments like minoxidil, RU58841, and finasteride is not permanent; stopping these treatments typically results in hair loss resuming. Beard hair can become permanent with minoxidil use, unlike scalp hair, which requires ongoing treatment to maintain gains.
community Minoxidil permanent face changes?
Excessive use of topical minoxidil led to unwanted facial changes and side effects. The user plans to switch to oral minoxidil with microneedling for hair regrowth.
community RU58841 Permanently Fixed Balding In Unexpected Way.
The user humorously describes trying various hair loss treatments, including minoxidil, finasteride, and RU58841, with a satirical twist involving psychedelic experiences and imaginary entities. They mistakenly used LSD instead of RU58841 and plan to continue experimenting with other substances.
community Does Nuking Scalp DHT Theoretically Make Minoxidil Gains Permanent?
Minoxidil gains are not permanent without continued use, even with DHT suppression. Combining treatments like Dutasteride, Finasteride, and RU58841 may help maintain hair, but stopping Minoxidil typically results in hair loss.
community Scalp Sunburns can cause permanent hair loss. UPF hats protect you.
Scalp sunburns can cause permanent hair loss, so wearing UPF hats is essential. Tretinoin and Tacrolimus users should be cautious of increased photosensitivity and potential scalp issues.
community Does discontinuing Minoxidil cause permanent damage to your hair?
Discontinuing Minoxidil typically returns hair to baseline, but some believe it may go below baseline temporarily. Continuing finasteride or dutasteride is recommended.
community If Minoxidil Beards are permanent, why should Finasteride be unable to keep Minoxidil Gains on the scalp?
Whether Finasteride can keep alive the hair gained by Minoxidil after quitting it, and why beard hairs are not as susceptible to miniaturization. It is suggested that scalp hair may be dependent on Minoxidil and that DHT could be countered with Finasteride to some extent, but there is no definitive data proving this.
community Which hairs are the ones "permanently" lost? The long wispy hairs, the short baby hairs, or both?
The conversation discusses identifying permanent hair loss and includes treatments like microneedling and biotin vitamins. The user is unsure whether the reduction in wispy hairs is due to hair revitalization or loss.
community Transient and Permanent Effects of Finasteride Use
Potential side effects of 5AR inhibitors like finasteride and dutasteride. Users debate risks, benefits, and personal experiences with these hair loss treatments.
community Is it possible that a shampoo can make you lose hair permanently ?
Shampoos are unlikely to cause permanent hair loss; hair loss is more likely due to male pattern baldness (MPB). The user is advised that losing hair in the shower is normal, and to avoid shampoos with sodium sulfate.
community Does tapering off minoxidil reduce permanent loss?
Tapering off minoxidil from 5% to 2% and gradually reducing frequency may help minimize hair loss, but some loss might be unavoidable. The discussion focuses on managing hair loss when discontinuing minoxidil.
community why are beard gains on min usually permanent?
Beard gains from minoxidil are usually permanent due to facial hair follicles' lower sensitivity to DHT. Scalp hair requires ongoing DHT suppression with treatments like finasteride, dutasteride, and RU58841 to maintain gains after stopping minoxidil.