Search
for

    Sort by

    Community Join

    510-540 / 1000+ results
      FCE 28260: A Forgotten 5α-Reductase Inhibitor

      community FCE 28260: A Forgotten 5α-Reductase Inhibitor

      in Research  330 upvotes 1 year ago
      FCE 28260 (PNU 156765), an under-explored 5α-reductase inhibitor, showcases promising results in research by Giudici et al., outperforming well-known treatments like Finasteride in reducing the conversion of testosterone to DHT. Its superior efficacy, demonstrated through lower IC50 values in both natural and human recombinant enzyme studies, suggests it could offer more effective management of DHT-related conditions. Additionally, its lower molecular weight hints at better potential for topical application, potentially offering advantages in treating conditions such as androgenic alopecia. Despite its potential, it has not advanced in development, possibly due to financial limitations, leaving its therapeutic prospects and side effect profile largely unexplored.

      community Trying to growth hair with medicine

      in Progress Pictures  14 upvotes 2 years ago
      The conversation is about a person using oral minoxidil, biotin multivitamins, dutasteride lotion, a hair growth serum with redensyl, capixyl, and procapil, ketoconazole with zinc shampoo, and monthly PRP treatments with a derma roller for hair growth. Someone encouraged them to continue with their regimen.

      community Any other treatments to still be hopeful for?

      in Research/Science  20 upvotes 2 years ago
      The conversation discusses the potential of new hair loss treatments, with a focus on pyrilutamide, gt20029, and topical alfatradiol, and the possibility of improving their effectiveness through methods like increased concentration and microneedling. Dutasteride is also mentioned as a stronger option.

      community Is there a big difference between name brand and cheaper hair fibres?

      in Product  1 upvotes 2 years ago
      A user is comparing the effectiveness and ingredients of name-brand hair fibers (Nanogen) versus cheaper generic options found on eBay. They are concerned about the presence of sodium chloride in the generic product and seek opinions on whether there is a significant difference in quality.

      community Highly experimental stack! Self Study Coming!

      in Research/Science  4 upvotes 2 months ago
      A 19-year-old plans to use an experimental hair loss treatment stack including micro-needling, Minoxidil, Pyrilutamide, Ketoconazole shampoo, and other unreleased compounds like PP405. Users advise against using unverified treatments and suggest sticking to proven options like Finasteride, with some recommending topical application to avoid side effects.

      community Musely s Exosome formulation looks interesting

      in Chat  13 upvotes 1 year ago
      Exosomes, cetirizine, melatonin, latanoprost, and caffeine are discussed as potential hair loss treatments. There is skepticism about the effectiveness of exosomes, especially in topical form, but some users report positive results.

      community Starting over at 40 with microneedling

      in Progress Pictures  10 upvotes 2 years ago
      A person had success with micro-needling for hair growth but stopped and noticed hairline recession. They plan to restart treatment at age 40, using micro-needling, oral minoxidil, finasteride, a laser cap, topical minoxidil with tretinoin, collagen, and other supplements.

      community RU58841 Permanently Fixed Balding In Unexpected Way.

      in Satire  123 upvotes 7 months ago
      The user humorously describes trying various hair loss treatments, including minoxidil, finasteride, and RU58841, with a satirical twist involving psychedelic experiences and imaginary entities. They mistakenly used LSD instead of RU58841 and plan to continue experimenting with other substances.

      community RU58841 legit source from europe and china

      in Product  1 upvotes 2 years ago
      A user is seeking advice on purchasing RU58841 from Biolab Shop in Poland and is looking for trustworthy sources that deliver to Germany from Europe or China. They are interested in the product's composition and user experiences.

      community Nanoxidil: a good substitute or a scam?

      in Treatment 1 year ago
      Nanoxidil is considered by some as a substitute for Minoxidil, but users report it as ineffective and expensive. Finasteride is recommended as a more effective treatment, often used with Minoxidil, microneedling, and ketoconazole.

      community Having Ru58841 mailed to my house

      in Research/Science  1 upvotes 4 months ago
      RU58841 can be ordered as a powder and compounded at home, but it should be stored at room temperature to avoid crystallization. Pyraulatmide may follow a similar principle.

      community My home made topical dutasteride

      in Finasteride/Dutasteride  3 upvotes 1 year ago
      The conversation is about a user making a homemade topical dutasteride solution to use alongside testosterone replacement therapy (TRT) and oral dutasteride. The user aims to reduce DHT locally at the testosterone injection site and on the scalp.

      community Ru58841 20mg….making my own solution

      in Treatment  1 upvotes 1 year ago
      The conversation is about making a 20mg/ml RU58841 solution for hair loss treatment using ethanol and propylene glycol. The user receives advice on calculating the correct amount of RU58841 powder needed.

      community 6 month results on topical min, oral fin, and microneedling

      in Progress Pictures  703 upvotes 3 years ago
      A user (Majestic-Head3874) who has had successful hair regrowth with the combination of topical minoxidil, oral finasteride and microneedling treatments. People are asking for details about these treatments and Majestic-Head3874 is sharing the regimen they used.

      community About GT20029's Efficacy and Strength

      in Chat  7 upvotes 3 years ago
      The conversation is about the effectiveness and production of GT20029, a drug being developed as a topical androgen receptor degrader for hair loss, and whether it can fully degrade androgen receptors or only partially. It also discusses the drug's potential unique working mechanism and synthesis by a company called Anagen.

      community Pyrilutamide / KX-826 | Discussion EU

      in Research/Science  4 upvotes 2 years ago
      The conversation is about a user expressing concerns over the safety of a new drug called Pyrilutamide (also known as KX-826) for hair loss. The user will only trust the drug if it's permitted by EU regulations and sold by a reputable company.

      community 21 months microneedling plus 15 months Fin, Great Results!

      in Update  72 upvotes 6 years ago
      A user shared their successful hair loss treatment using 1.25mg finasteride daily, 2.5mm microneedling every 1-3 weeks, zinc pyrithione shampoo, occasional scalp massages, and 40% glycolic acid on temples. They reported significant progress over 21 months.

      community cosmeRNA finally now it's pyrilutamide turn

      in Chat  48 upvotes 3 years ago
      Hair loss treatments discussed include cosmeRNA, minoxidil, finasteride, RU58841, and pyrilutamide. Users debate effectiveness, side effects, and upcoming treatments, with some expressing skepticism and others optimism.

      community You guys were spot on and I love you for it.

      in Update  90 upvotes 1 month ago
      The user reported using finasteride 1mg, minoxidil 5% topical, and microneedling 1mm weekly for six months with no side effects. The conversation includes questions about the effectiveness and methods of these treatments, with some users sharing their experiences and advice.

      community Have any of you given Nanoxidil a try?

      in Product  4 upvotes 4 years ago
      Nanoxidil is discussed as a potential alternative to Minoxidil for hair loss, with some users reporting better results and improved hair strength. However, concerns about its lack of FDA approval and potential scalp dryness are noted.