PP405 is a promising new treatment for hairloss that activates dormant stem cells in hair follicles, potentially bypassing the effects of DHT. It is currently in phase 2 trials and could be available between 2027 and 2030, but it is not considered a definitive cure.
The user is experiencing increased hair shedding, scalp sensitivity, and itching despite using finasteride for four months, and has tried various shampoos without relief. They are advised to consult a dermatologist for potential scarring alopecia and consider other treatments like adding Dutasteride.
The user experienced hair thinning in the middle of their head despite using finasteride and minoxidil and having a hair transplant. They are concerned about the thinning and considering shaving their head, while being advised to continue treatment and manage stress.
Pumpkin seed oil is a weak natural DHT inhibitor and not effective for significant hairloss. Effective treatments include finasteride, minoxidil, and other medications.
The user is frustrated with hairloss treatments like finasteride, minoxidil, dutasteride, and oral minoxidil, which have been ineffective and caused scalp itching. They are skeptical about these treatments' effectiveness and consider alternative options like ketoconazole shampoo and RU58841.
User obsessed with hairloss prevention shares collection of treatments, including oral and topical finasteride, minoxidil, dermapen, and more. Others suggest adding RU58841, laser helmet, and PRP, while some advise dropping certain treatments for long-term manageability.
PP405 is discussed as a potential treatment for hairloss, with excitement about its promise but skepticism about its current effectiveness. Users mention combining it with treatments like minoxidil, finasteride, and microneedling, but emphasize it is not a cure.
A user shared their experience with hairloss treatments, including topical minoxidil, finasteride, RU58841, and microneedling, noting significant hair regrowth except at the hairline. They plan to start oral minoxidil and switch to a combination treatment, while another user mentioned that some miniaturized hairs may not fully recover.
Dutasteride can drastically reduce sebum production, leading to dryer hair and shedding. Alternating shampoos and periodic silica supplementation can improve hair quality and thickness.
The user experienced significant hairloss after 9 months of using 0.5mg dutasteride and oral minoxidil, possibly due to alopecia areata. It is advised to consult a doctor for accurate diagnosis and treatment, as dutasteride and finasteride may not be effective.
The user discusses a galenic hair lotion containing progesterone, estradiol, cyproterone, hydrocortisone butyrate, and cetirizine pheniramine, which has effectively stopped their hairloss over two years. They are curious about the compatibility of finasteride with the lotion's components and note that their trichologist has successfully used minoxidil and finasteride in similar treatments for others.
A 21-year-old experienced hormone changes after using self-made topical finasteride for hairloss, including a 20% decrease in DHT, a 47% increase in testosterone, and a 39% increase in estradiol. The user previously used minoxidil and microneedling but is now seeking ways to balance hormones, possibly through supplements or dosage adjustments.
A user with mild psoriasis on the scalp is using finasteride, topical minoxidil, and dermarolling for hairloss but plans to stop minoxidil on the crown due to psoriasis aggravation. Suggestions include switching to a lipid-based minoxidil, using Ketoconazole shampoo, or trying oral minoxidil.
The user is experiencing hair thinning and brittleness, possibly due to Telogen Effluvium, which affects body hair and may be linked to stress or nutrition. They are considering using finasteride for treatment but are unsure if it will address their symptoms.
The user experienced hair repigmentation and attributes improvements in hair and overall health to a carnivore diet, Boron, and Selenium supplementation. They stopped using finasteride after 20 years, noticed increased testosterone and libido, and observed hair regrowth with RU58841.
A 23-year-old male is experiencing diffuse hairloss and miniaturization, possibly due to high IGE levels after using tofacitinib. He seeks advice and has not yet consulted a dermatologist.
Nizoral 2% is popular for maintaining scalp health and reducing inflammation, though its effectiveness for hairloss is debated. Some users combine it with finasteride for better results, while others find it drying or ineffective.
A 23-year-old male switched to a topical solution containing Fin 0.1% and Min 5% from a previous solution with Fin 1% and Min 5%, noticing increased hair shedding. He is concerned about losing around 50 hairs while using ketoconazole shampoo.
The user follows an intensive hairloss protocol including dutasteride, biotin, black tea, pumpkin seed oil, peppermint shampoo, rosemary conditioner, mukemame, soy milk, lycopene, garlic, magnesium, chamomile, spicy food, citrus bergamot, zinc, multivitamins, kefir, and Greek yogurt. They plan to alternate between pumpkin seed oil and safflower oil and will share before and after pictures.
The user is using caffeine shampoo with baicapil, microneedling, massage, and procapil lotion for hairloss. Replies suggest the user is balding and recommend finasteride.
Prostaglandin balance affects hairloss, particularly in conditions like Lichen Planopilaris, where an imbalance can lead to hair follicle damage. Treatments mentioned include prostaglandin analogs and Pioglitazone HCL, with a focus on maintaining prostaglandin equilibrium for potential hair regrowth.
The conversation is about the role of testosterone in hairloss and the effectiveness of different treatments. The conclusion is that DHT is the main culprit for hairloss, and finasteride has been proven to work long-term in maintaining and regrowing hair. Testosterone may have a minor effect, but it is not the primary cause of hairloss.
RU58841 worsened hair condition, causing thinning and unusual patterns. The user stopped using it two months ago but hasn't seen recovery, and there's speculation about androgen receptor upregulation.
A 21-year-old is experiencing significant hairloss and considering treatments like dutasteride, minoxidil, and possibly a hair transplant. Others share their experiences with finasteride, scalp micropigmentation, and hair transplants, discussing the emotional impact and offering support.
PP-405, a potential hairloss treatment, shows promise in stimulating dormant hair follicles and may help with various hairloss types. Current treatments like Minoxidil are still recommended as PP-405 is in early trials and may take years to become available.
A 24-year-old with male pattern baldness experienced side effects from oral finasteride and switched to a topical minoxidil/finasteride combination, later incorporating daily shampooing and scalp brushing to manage hairloss and dandruff. After initial shedding, the regimen led to reduced hairloss and new hair growth, with the user now using a densita mf combination (5% minoxidil/0.1% finasteride + redensyl) nightly.
A user is concerned about using Alpicort, which contains Prednisolone and Salicylic Acid, for male pattern baldness. They are unsure if it will help or worsen their condition and are seeking advice.
A 25-year-old male experiencing hairloss and thinning since age 20 is seeking advice on effective DHT inhibitors. He lists various oral and topical treatments, excluding Minoxidil due to adverse effects.