The user seeks alternatives to PropyleneGlycol (PG) for delivering topical finasteride due to scalp irritation. They consider using Propanediol 1,3 and ask for other suggestions.
A user asked if olive oil can replace propyleneglycol or glycerin in topical finasteride preparation. Another user advised against it, suggesting MCT oil instead due to olive oil's potential to worsen dandruff and seborrheic dermatitis.
The conversation discusses adjusting the isopropyl alcohol, propyleneglycol, and water ratios in a topical finasteride solution for better scalp comfort and less dandruff. The user considers using 20ml IPA, 25ml PG, and 15ml water in a 60ml bottle, moving away from mixing finasteride with topical minoxidil.
User experienced scalp irritation from Kirkland 5% liquid minoxidil, likely due to propyleneglycol. They are seeking non-PG liquid alternatives that are affordable.
The user is experiencing an allergic reaction to propyleneglycol in Kirkland minoxidil and is considering switching to a foam version or a low-PG minoxidil solution. They are also contemplating oral minoxidil but are concerned about its long-term safety.
A user allergic to propyleneglycol seeks alternatives for a DIY topical finasteride solution, considering glycerin or glycerol-based vehicles. Another user suggests a recipe using propanediol, DMSO, MCT oil, and peppermint oil, incorporating minoxidil, dutasteride, and finasteride.
The conversation discusses creating a DIY topical finasteride solution for someone allergic to propyleneglycol, with suggestions to use glycerin or a glycerol-based vehicle instead. The user also mentions using foam minoxidil.
The user is seeking alternatives to propyleneglycol and glycerin for mixing with RU58841 due to allergies and greasiness. Suggestions include reducing glycerin and considering stemoxydine as a solvent.
A user is seeking UK-based sources for propyleneglycol and ethanol to dilute topical finasteride for hair loss treatment. They currently order from MinoxidilMax but want a faster shipping option.
The conversation discusses the use of ethanol and propyleneglycol (PG) in topical solutions for hair loss treatments, specifically Minoxidil. The user dislikes the texture of PG and questions the ideal ratio and necessity of PG in these solutions.
The conversation is about the effectiveness of Minoxidil formulations with different alcohol and propyleneglycol (pg) ratios. The user finds that a formulation with 20% pg and 80% ethanol dries faster but is concerned about absorption time.
The conversation discusses the use of Finastopic, a carrier for finasteride solutions by Isdin, and compares it to a standard propyleneglycol (PG) solution. The user was prescribed a 1% finasteride solution using Finastopic and has been using a self-compounded 0.025% topical finasteride with minoxidil.
Topical finasteride may have higher systemic absorption and lower efficacy when using a PropyleneGlycol/Ethanol formulation compared to the hydroxypropyl chitosan (HPCH) formulation. The safety profile of topical finasteride relies heavily on the HPCH formulation, and using standard solutions might lead to different pharmacokinetics.
A user is making their own dutasteride solution using MCT oil but is concerned about its effectiveness and bioavailability. They are considering using propyleneglycol or adding ethanol for better results, while others suggest the current dosage might be excessive.
Switching to a DIY topical finasteride solution using ethanol, glycerin, and distilled water instead of propyleneglycol for a gentler application. Users report positive results with both DIY solutions and a low PG minoxidil and finasteride product from India.
A user is seeking recommendations for purchasing Minichek 5% solution, a PG-free minoxidil, due to a contact allergy to propyleneglycol. They are looking for an affordable option comparable in price to Kirkland or Amazon brand minoxidil.
Homemade topical finasteride solutions are discussed, with one user using 30% ethanol, 50% propyleneglycol, and 20% water. Alternatives like dissolving finasteride pills in minoxidil and using stemoxydine are also mentioned.
A user is seeking a UK source for a combined minoxidil and RU58841 solution that doesn't contain scalp-irritating ingredients. They specifically want a product without propyleneglycol (PG).
Koshine KX-826 has different versions, and the green version uses a plant-based carrier that may be less irritating for those sensitive to propyleneglycol. Users report irritation with some versions of KX-826.
Switching from propyleneglycol to glycerin in topical finasteride may reduce systemic absorption and side effects while maintaining local scalp DHT suppression. Concerns exist about glycerin's ability to deliver the full dose to hair follicles.
The conversation discusses the best ethanol and propyleneglycol ratio for homemade topical finasteride, with a focus on absorption and drying issues. The user shares their experience using a 50% propyleneglycol, 30% ethanol, and 20% water solution, and considers adjusting the ethanol content for better results.
The conversation discusses two methods for making topical finasteride: using ethanol and propyleneglycol or mixing it with topical minoxidil. The focus is on solubility and absorption, with a suggestion to crush pills finely and possibly mix with minoxidil at a slightly elevated temperature.
The user is considering adding RU58841 to liquid minoxidil without propyleneglycol (PG) due to an allergy and is asking if this combination is effective and if PG is necessary. They have been using finasteride and minoxidil foam, plan to use RU58841 with liquid minoxidil in the evening, and continue finasteride.
The conversation discusses using topical finasteride with propyleneglycol, which causes scalp dryness or dandruff. The user also uses Nizoral, Nioxin, and DHT oil, and considers using a scalp conditioner to alleviate dryness.
RU58841 powder is mixed with a 70% ethanol and 30% propyleneglycol solution, with some users seeking PG-free alternatives. Minoxidil is also mentioned as a treatment option.
Minoxidil can cause scalp itchiness, often due to propyleneglycol, and users suggest alternatives like foam formulations without PG, using moisturizing oils, or reducing application frequency. Some recommend ketoconazole or zinc pyrithione shampoos to help with inflammation and itchiness.
A new alcohol-free, propyleneglycol-free topical finasteride foam is available for prescription in Canada and the USA, offering a cleaner alternative for hair loss treatment. The product also offers a combination of 0.1% finasteride with 5% minoxidil and aims to be affordable and less irritating for sensitive scalps.
The conversation is about the best vehicle for RU58841, comparing trichosol and Garnier/Vichy Stemoxydine, avoiding propyleneglycol (PG) or ethanol due to previous scalp damage. The user is also seeking sources for these products in the EU.