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      community Don’t Get Too Hyped About PP405. We've Seen This Movie Before.

      in Research/Science  218 upvotes 11 months ago
      PP405 is a new hair loss treatment showing early promise with a 20% hair density increase, but skepticism exists due to past failures of similar treatments like Pyrilutamide, RU58841, and Bimatoprost. Users debate its potential effectiveness, with some hopeful due to Google's involvement, while others urge caution without more evidence.

      community Almost 3 weeks on Pyrilutamide-Update

      in Update  12 upvotes 3 years ago
      The user has been using Actifolic Pyrilutamide 0.5% once daily for almost three weeks without noticing any side effects or progress. Other users suggest that significant results typically take 3-6 months to appear.

      community Comparison of the efficacy of topical minoxidil 5% and adenosine 0.75% solutions on male androgenetic alopecia and measuring patient satisfaction rate

      in Minoxidil  17 upvotes 7 years ago
      Comparing the effectiveness of minoxidil 5% and adenosine 0.75% for treating male androgenetic alopecia, and measuring patient satisfaction rate; results showed that adenosine is comparable to minoxidil but provides quicker results, however availability of products with adenosine is much less than those with minoxidil.

      community Recommended AHK-Cu peptide brand?

      in Treatment  1 upvotes 1 year ago
      AHK-Cu peptide is considered better than GHK-Cu for hair growth. The user is seeking recommendations for trusted AHK-Cu peptide brands with third-party testing.

      community Ru58841 2% ED 9 month progress

      in Progress Pictures  17 upvotes 3 years ago
      A user shared their 9-month progress using RU58841 at 2% daily for hair regrowth, initially starting at 5% but reducing the dose due to early signs of gynecomastia, which has since mostly resolved. They achieved their goal of regrowing hair at the temples and hairline.

      community Anyone know cheapest/best way to source RU58841 for Aussies?

      in Product  2 upvotes 2 months ago
      The conversation is about sourcing RU58841 for hair loss treatment in Australia and discusses the lack of effective alternatives. Alternatives mentioned include Kx826, fluridil, cb, alfatradiol, and topical spiro, but they are considered weak compared to RU58841.

      community My progress last 4 months min 10% /prp/Fotona laser

      in Progress Pictures  12 upvotes 2 years ago
      A user shared their 4-month progress using a serum with Minoxidil 10%, Progesterone, Azelaic acid, Retinoic acid, Latanoprost, and Hydrocortisone, along with PRP and Fotona laser treatments. They are pleased with the results and plan to continue with more PRP and laser sessions, without using Finasteride.

      community How deep do you microneedle and do you bleed?

      in Microneedling  5 upvotes 2 years ago
      The conversation discusses microneedling for hair loss, with the original poster experiencing pinpoint bleeding after using needles of 1.25mm and 0.5mm, possibly due to adding GHK-Cu to their treatment regimen. They are inquiring if others bleed at similar depths.

      community Am I doing dermastamping wrong?

      in Technology  6 upvotes 2 years ago
      The user uses a 1.5mm derma stamp weekly for hair loss and applies minoxidil afterward, feeling a slight burn but no bleeding. They question if bleeding, seen in others using a derma pen, indicates proper technique.

      community Is pyri and gt20029 worth the hype????

      in Update  6 upvotes 2 years ago
      The conversation discusses the effectiveness of pyrithione zinc and GT20029 for hair loss. Specific treatments mentioned include Minoxidil, finasteride, and RU58841.

      community Choose your topical antiandrogen and tell me why

      in Product  6 upvotes 1 year ago
      The conversation is about choosing a topical antiandrogen for hair loss, with options including RU58841, CB0301, Pyrolutamide, Alfatradiol, and Fluridil. Users discuss their preferences and reasons for selecting specific treatments.

      community waiting for hope DIY pp405 guy that will save us😡😡😔

      in Satire  38 upvotes 7 months ago
      People are discussing the potential of a new hair loss treatment, pp405, and its approval timeline, comparing it to existing treatments like Minoxidil and finasteride. There is skepticism about its effectiveness and concerns about the time it will take for approval and availability, especially in Europe.

      community Homemade finasteride foam similar to minoxidil foam

      in Product 1 year ago
      A user is seeking advice on creating a homemade finasteride foam similar to over-the-counter Minoxidil foam, due to issues with glycerin and propylene glycol in their current solutions. They are considering using a mixture of ethanol/alcohol and water for the foam.

      community Pyrilutamide solution question

      in Research/Science  8 upvotes 3 years ago
      The conversation is about the stability of pyrilutamide in different solutions. The user is asking if a 70/30 ethanol/pg solution with 4% water will degrade pyrilutamide.

      community Finasteride, 2 years [progress pictures]

      in Progress Pictures  643 upvotes 6 months ago
      The user shared their two-year progress using finasteride, noting hair stabilization without side effects and no use of minoxidil. They plan a hair transplant and emphasize finasteride's role in maintaining hair rather than regrowing it.

      community Pyrilutamide 0.5 or 0.025% topical fin for maintaining?

      in Basic Questions  91 upvotes 1 month ago
      The user is considering switching from pyrilutamide to 0.025% topical finasteride due to concerns about effectiveness and past side effects from a scalp elixir. They aim to maintain hair until new treatments like breezula or GT00029 become available.

      community A Technical Question About Pyrilutamide

      in Research/Science  5 upvotes 2 years ago
      Pyrilutamide is believed to be more effective than RU58841 and 1 mg finasteride in treating hair loss, with no systemic hormonal effects and the potential to block more than 31% of scalp DHT. It may also antagonize scalp testosterone due to its action as an androgen receptor antagonist.

      community 8 months - 2,5mg OM / Topical MinFin

      in Progress Pictures  176 upvotes 3 years ago
      User shares 8-month hair growth progress using 2.5mg oral minoxidil and 2ml topical minoxidil/finasteride mix. Others comment on noticeable improvement and discuss user's journey and treatment details.

      community PP405 Hairloss Reversal and Hairline Restoration

      in Treatment  5 upvotes 4 months ago
      PP405 may induce new hair growth but cannot revive completely dead follicles, and its effectiveness on hairlines is uncertain. It is expected to be available by mid-2028, but users are advised to manage expectations and consider using other treatments like minoxidil and finasteride.

      community Extreme regimen and still miniaturized hairs. AGA is just impossible to beat.

      in Insane  35 upvotes 3 years ago
      A user's extreme regimen for hair loss, which includes taking oral and topical medications such as minoxidil, dutasteride, cyproterone acetate and bicalutamide, but still experiencing miniaturization. Suggestions were made to try other treatments such as RU58841 and Pyrilutamide, while also considering mental health treatment and advice on lookmaxxing.

      community Coegin Pharma to release Follicopeptide (FOL005) by Q2 2025

      in Treatment  120 upvotes 1 year ago
      Follicopeptide (FOL005) by Coegin Pharma will launch as a cosmetic hair growth treatment by Q2 2025, showing similar efficacy to finasteride. Users discuss the benefits and skepticism of releasing hair loss treatments as cosmetics rather than drugs.

      community Ggs in the chat. ✌🏼 A year and a half on it.

      in Progress Pictures  371 upvotes 1 month ago
      The user has been using finasteride 1mg daily, oral minoxidil 5mg daily, and microneedling weekly, experiencing initial side effects like ball pain and weaker erections, which resolved over time. They reported improved hair density after 7 months and recommend adding derma stamping to the routine for better results.