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      community DLQ01: A Better "Minoxidil" PGF2a synthetic analogue.

      in Research/Science  3 upvotes 1 year ago
      DLQ01, a prostaglandin F2α analog, shows promise for hair growth by directly stimulating PGE2/PGF receptors without needing conversion, and can be combined with minoxidil and retinoids like tretinoin for enhanced effectiveness. Minoxidil's efficacy may be reduced by COX-1 inhibitors, but using prostaglandin analogs like Latanoprost or Bimatoprost can help maintain its effectiveness.

      community 3 months on Finasteride-Minoxidil-Microneedling 36M

      in Is this regrowth?  2 upvotes 3 months ago
      A 36-year-old male has been using finasteride, 5% minoxidil foam, and microneedling with a 0.75mm dermastamp or Dr. pen for three months. He notices thicker hair and reduced hair loss, with high testosterone and normal DHT levels, while managing prolactin levels with vitamin B6.

      community 8 mo fin, 2mo min, 2mo vitamin D

      in Progress Pictures  45 upvotes 2 years ago
      A user shared progress pictures after 8 months of finasteride, 2 months of minoxidil, and 2 months of vitamin D. The post shows significant hair improvement despite some light differences in the photos.

      community What blood test to do before starting fin?

      in Finasteride/Dutasteride  1 upvotes 3 months ago
      A user is considering starting finasteride for hair thinning but is concerned about side effects like low libido and gynecomastia. They plan to consult a dermatologist and are advised to test DHT, testosterone, and estradiol levels.

      community Looks like I’m allergic to propylene glycol..

      in Minoxidil  4 upvotes 4 years ago
      The user is experiencing an allergic reaction to propylene glycol in Kirkland minoxidil and is considering switching to a foam version or a low-PG minoxidil solution. They are also contemplating oral minoxidil but are concerned about its long-term safety.

      community If PP405 works it will be fkn impossible to buy it.

      in Technology  102 upvotes 7 months ago
      PP405 is a potential hair loss treatment that may activate dormant hair follicles, but there are concerns about its effectiveness, cost, and side effects. Users discuss treatments like minoxidil, finasteride, and RU58841, expressing skepticism about PP405's long-term success and accessibility.

      community Back from the depths - 24M, big 3

      in Progress Pictures  70 upvotes 3 years ago
      A 24-year-old man saw hair loss improvement after 5 months using 1 mg finasteride daily, 5% minoxidil nightly, weekly microneedling with a Dr. Pen A6 at 1.5mm, daily biotin (at least 10,000 mcg), and using a shampoo for thinning hair every other day. He experienced no side effects and confirmed his health with bloodwork.

      community Approve PP405 quickly you coward

      in Satire  193 upvotes 11 months ago
      Pelage Pharmaceuticals is developing PP405, a topical treatment for hair growth, currently in Phase 2a trials. There is skepticism about the company's claims, and no fast-tracking approval timeline has been detailed.

      community How would you react if PP405 isn't successful in phase 3 trials?

      in Chat  23 upvotes 6 months ago
      People are discussing their reactions if PP405 fails in phase 3 trials, with some expressing skepticism and others holding onto hope for future treatments like GT20029 and Breezula. Many mention continuing with existing treatments like minoxidil and finasteride, while others express disappointment and consider alternative solutions.

      community which is better ; minoxidil with more alcohol or more pg?

      in Minoxidil  4 upvotes 3 years ago
      The conversation is about the effectiveness of Minoxidil formulations with different alcohol and propylene glycol (pg) ratios. The user finds that a formulation with 20% pg and 80% ethanol dries faster but is concerned about absorption time.
      There is hope guys, M28 75 days of Fin&Min

      community There is hope guys, M28 75 days of Fin&Min

      in Journals / Progress Pictures  91 upvotes 6 months ago
      A user shared progress pictures showing improved hair fullness after 75 days using 2.5mg oral minoxidil daily, 1mg oral finasteride every other day, a 1.5mm dermastamp weekly, and daily scalp massages. They report seeing early positive results.

      community Green tea/ soy Isoflavones supplements for MPB

      in Product  4 upvotes 5 years ago
      Green tea extract and soy isoflavones may help with hair loss by inhibiting DHT and providing additional health benefits. Combining these with finasteride and possibly using nizoral shampoo could enhance effectiveness in managing hair loss.

      community 7 months progress. fin 1.25 mg, oral min 2.5 mg, keto shampoo, micro-needling once per month. M/32

      in Progress Pictures  82 upvotes 2 years ago
      A user shared a 7-month hair loss treatment progress using finasteride 1.25 mg, oral minoxidil 2.5 mg, ketoconazole shampoo, and monthly micro-needling, noting denser hair and improved quality but no significant regrowth. They experienced mild testicular discomfort and heart palpitations, considering switching to topical minoxidil to avoid side effects.

      community 3 months in, min/fin/microneedle

      in Progress Pictures  97 upvotes 3 years ago
      A user's progress with using Minoxidil, finasteride, and microneedling to treat hair loss; another user mentioned a Japanese study that found better results for hairy individuals on finasteride.

      community Topical fin formulation question

      in Finasteride  91 upvotes 1 year ago
      A user is making a homemade topical finasteride solution by dissolving crushed finasteride tablets in ethanol and PG. They are unsure if the final solution maintains the intended concentration after filtering and are considering adding more ethanol to ensure accuracy.

      community Good News, PP405 is out on Shopee

      in Product  266 upvotes 4 months ago
      A product called "PP405 Hair Follicle Serum" is being sold on Shopee, claiming to cure baldness without clinical trials or FDA approval, but users are skeptical and refer to it as "snake oil." Some users discuss testing the product's contents, while others share their experiences with hair loss treatments like finasteride.

      community Phase 3 of pyrilutamide (kx-836) analysis of the efficacy

      in Research/Science  11 upvotes 2 years ago
      The conversation discusses the less impressive results of Pyrilutamide (kx-836) in phase 3 compared to phase 2, with a suggestion that a longer study might show more significant results. One user reports personal success with Pyrilutamide, experiencing no further hair loss and gradual regrowth.

      community Has anyone used Magnesium L-Threonate ?

       70 upvotes 7 years ago
      Magnesium L-Threonate may help treat balding by reducing DKK-1 expression without affecting DHT. Users discuss its potential effectiveness and application methods, with some considering trying it topically.

      community 3 Mo Progress Fin/Min- Sept.-Dec

      in Is this regrowth?  22 upvotes 1 year ago
      The conversation is about a user sharing their positive progress with hair regrowth using oral minoxidil, biotin, finasteride, and other supplements. The user also mentions using a HIMS oral fin/min combo and receives advice and encouragement from others.