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      community P-1075: a BETTER version of Minoxidil

      in Research/Science 5 months ago
      P-1075 is a more potent hair growth agent than Minoxidil, but it poses significant heart risks, making it unsafe for use. Despite promising results in macaques, concerns about its cardiotoxicity in rats have halted its development.

      community Caffeine + Dimethylglycine (DMG) Shampoo research

      in Research/Science  6 upvotes 1 year ago
      A user discusses the potential of caffeine and DMG in shampoo for treating hair loss, citing a pending patent and personal plans to test it. They find it more convenient than using minoxidil, tretinoin, and microneedling.

      community Helicobacter's concocted serum v1

       7 upvotes 7 years ago
      A custom-made serum based on double-blind studies for AGA, which includes natural ingredients such as rosemary oil, procyanidin B-2, saw palmetto extract, curcuma aeruginosa, pumpkin seed oil and castor oil. The user has updated their recipe to include apple poly procyanidin B-2 4% concentration and other ingredients before topping it off with Pura d'or serum.

      community Can i trust this oral minoxdil?

      in Minoxidil 1 month ago
      The conversation is about concerns over the authenticity of oral minoxidil for hair loss treatment, with fears it might contain finasteride despite labeling. Users reassure that if it states minoxidil only, it should be trusted, and mention that Indian drugs are generally okay.

      community Scams by hair transplant, prp, GFC clinics i faced 24/m. Is there a dna test that shows which meds are more suitable to individual saw a post link below

      in Is this regrowth? 6 months ago
      The user shares their experience with hair loss treatments, including oral finasteride, oral minoxidil, and a topical lotion for dandruff, expressing dissatisfaction with past treatments like PRP and hair transplants. They seek advice on a DNA test to determine suitable medications and express frustration with dermatologists' advice.

      community Have some questions about prescription I got from a trichologist

      in Chat  1 upvotes 11 months ago
      A trichologist prescribed Biotrade Sebomax HR Anti-Hair Loss Tonic, Spectral DNC-N Nanoxidil, Hairfollic Him/Man Vitamins, and Bosley MD DHT blocking supplements instead of finasteride due to potential risks at age 21. The user questions the legitimacy of the treatment and considers seeking a second opinion.

      community Any sources on Geranium sibiricum extract?

      in Product 4 years ago
      The conversation discusses the use of Minoxidil and finasteride for hair loss and explores the potential of Geranium sibiricum extract as a safer alternative. It highlights the difficulty in finding this specific extract and suggests considering other plants with similar compounds, like Indian gooseberry.

      community RU58841 KB Solution vs PG + Ethanol

      in Research/Science  6 upvotes 2 years ago
      The conversation discusses the differences between KB solution and PG + Ethanol solution for RU58841 in treating hair loss. It compares the effectiveness and properties of these two solutions.

      community Sandalore (Givaudan) concentration application

       12 upvotes 7 years ago
      The conversation discusses using Sandalore for hair loss treatment, with a focus on finding the correct concentration for a topical lotion. The consensus is to start with a 0.1% concentration due to potential scalp irritation at higher levels.

      community Can we trust indian medication?

      in Chat  7 upvotes 1 year ago
      The conversation discusses the trustworthiness of Indian medications for hair loss, with some users mentioning they have purchased Minoxidil, finasteride, and RU58841 from India. Concerns include dosage and ingredient variations, but no harmful effects are noted.

      community Need help with RU58841 (preparation + dosage).

      in Treatment  3 upvotes 9 months ago
      The conversation is about using RU58841 for hair loss treatment, specifically mixing it with minoxidil without propylene glycol due to an allergy. The user is considering starting with a lower concentration of RU58841 and making smaller batches to maintain efficacy.
      FCE 28260: A Forgotten 5α-Reductase Inhibitor

      community FCE 28260: A Forgotten 5α-Reductase Inhibitor

      in Research  330 upvotes 1 year ago
      FCE 28260 (PNU 156765), an under-explored 5α-reductase inhibitor, showcases promising results in research by Giudici et al., outperforming well-known treatments like Finasteride in reducing the conversion of testosterone to DHT. Its superior efficacy, demonstrated through lower IC50 values in both natural and human recombinant enzyme studies, suggests it could offer more effective management of DHT-related conditions. Additionally, its lower molecular weight hints at better potential for topical application, potentially offering advantages in treating conditions such as androgenic alopecia. Despite its potential, it has not advanced in development, possibly due to financial limitations, leaving its therapeutic prospects and side effect profile largely unexplored.

      community Comparison of options: topical vs medication

      in Female  1 upvotes 1 year ago
      A user diagnosed with AGA is seeking advice on hair loss treatments, comparing topical Minoxidil, Spironolactone, and Finasteride to oral medications and natural methods like dermastamping, PRP, and LED light. They are concerned about side effects and effectiveness, especially given their existing fatigue.

      community New Treatments, and a Huge Group Buy with Lots of Research

      in Research/Science  109 upvotes 2 years ago
      A user is organizing a group buy for various compounds aimed at reversing hair loss and gray hair, and improving brain health and fat loss. The user has developed a treatment plan based on extensive research and is inviting others to participate, with the option to choose only the compounds they need.

      community GT20029 Big Phase 2 Update Results!

      in Research/Science  50 upvotes 4 months ago
      GT20029 showed promising results for hair growth in a Phase II trial, with the 1.0% twice-weekly regimen being the most effective. Some users expressed skepticism and humor about the product's effects and market availability.

      community How to prepare topical spironolactone?

      in Female  5 upvotes 1 year ago
      A user with androgenic alopecia seeks advice on making topical spironolactone from pills due to poor reactions to the oral form and its unavailability in their country. They are looking for guidance on preparing it themselves.

      community Do you think oral minoxidil will become the standard for hair loss in 2026?

      in Minoxidil  141 upvotes 2 months ago
      Oral minoxidil is considered more convenient and effective for some users, with positive results reported, but concerns about side effects and availability persist. Finasteride remains a standard treatment, while some users explore combinations with other treatments like dutasteride and laser devices.

      community Creating Your Own Topicals: A Guide

      in Research/Science  71 upvotes 3 years ago
      Creating a carrier solution for topical hair loss treatments using ethanol, propylene glycol or glycerin, and instructions on creating topical finasteride. Different recipes are provided with varying ratios of alcohol to humectant.

      community Diluting Melatonin Sublingual Spray

      in Treatment  2 upvotes 2 years ago
      A user wants to dilute a melatonin sublingual spray to 0.0033% for use as a topical hair loss treatment. They ask if distilled water can be used for dilution and how much is needed for stability over months.