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PP405, a topical LDH inhibitor, has shown to stimulate hair follicle stem cell proliferation in humans with moderate hair loss. They are advancing to more detailed trials this year.

The conversation is about someone who has not seen hair regrowth after 6 months on finasteride alone, asking if others have experienced delayed results. Some responses indicate that results can sometimes be seen after 12 months, with full effects up to 24 months.

The conversation is about skepticism regarding new hair loss treatments until they are FDA approved. People have been joking about treatments being 5-7 years away for decades.

The conversation is about a user planning to undergo a hair transplant and seeking information on clinics that perform Verteporfin treatment. A user suggests Dr. Barghouthi might offer this service.

A person is treating their hair loss with oral minoxidil (2.5mg), derma stamping, and dutasteride (0.5mg) for nearly a year but still feels their hair isn't dense enough to grow out. Commenters are generally supportive, noting progress and suggesting it may look denser than the person perceives.

The user shared a 15-month hair loss treatment update using Dutasteride (0.5mg/day), Minoxidil (5% foam twice daily), Nizoral (1% every 3 days), and a 1.5mm derma roller (twice a month), along with a multivitamin, exercise, low sugar diet, hydration, and consistent sleep. They started seeing results after 6-9 months, with significant improvement at the 1-year mark, and apply Minoxidil the day after derma rolling.

The conversation is about a user's 3-month hair regrowth progress using finasteride, minoxidil, and a 0.5mm dermaroller, with recent addition of caffeine shampoo. Users are responding positively and inquiring about application methods.

After 6 years of finasteride losing effectiveness for hair loss, the user switched to dutasteride and topical minoxidil, seeing good progress after 7 months without significant side effects. They transitioned from finasteride to dutasteride over 2 months against doctor's advice.

A new hair loss treatment called TDM-105795 is discussed as a potential replacement or add-on to Minoxidil. Users express hope for new effective treatments.

User shares 8-month progress on oral finasteride and minoxidil, noting initial success followed by a second shed. They seek advice on drug resistance and pill efficacy, with responses suggesting to push through the shed and consider the impact of cycling off minoxidil.

The conversation discusses potential future hair loss treatments, including SCUBE3, hair follicle cloning, and GT20029, with mentions of past disappointments like CosmeRNA and hopes for treatments like Verteporfin for infinite donor hair.

User applied Xyon fin topical gel daily, used Augstinus Bader shampoo, conditioner, and scalp treatment, and applied argan oil twice a week. No Minoxidil, no dermarolling, and no side effects were reported.

A person using Minoxidil, Finasteride, Microneedling, and recently added Tretinoin is experiencing heavy shedding and thinning hair. They suspect Tretinoin has made them respond to Minoxidil and are seeking others with similar experiences.

The user reported significant hair growth after 8 months using a topical solution of 0.25% Finasteride and 8% Minoxidil, with no side effects. They also performed micro-needling and took multivitamins.

A user shared their experience with hair loss treatments, including finasteride, minoxidil, and RU58841, which improved their hair from a diffuse NW3 to a solid NW2 - 2.5. They noticed significant changes in how people treated them after regrowing their hair, suggesting that attractiveness can greatly impact social interactions and opportunities.

The conversation discusses the effectiveness of minoxidil for hair loss after one month of use, with a user questioning if complete hair regrowth is possible and another suggesting the perceived improvement may be due to lighting differences rather than actual hair growth.

A man started treating hair loss in April 2022 with 1mg finasteride every other day and weekly derma rolling. By September 2023, he added daily biotin and twice-daily 5% minoxidil foam to his regimen.

The conversation is about disappointment with pyrilutamide's performance as a hair loss treatment, with some users expressing interest in other treatments like Verteporfin, GT20029, and RU58841, while others suggest sticking with established treatments like finasteride or dutasteride.

Pyrilitamide (KX-826) did not show significant improvement in hair count compared to placebo after 6 months. It's unclear if it can maintain hair at baseline.

After 2.5 years of using 1mg finasteride daily, 5% minoxidil foam twice daily, and weekly micro-needling, the user reports thicker, healthier hair without further loss. They noticed initial regrowth at 3 months, with significant improvement up to 18 months, and no negative side effects from the treatment.

A user's positive early results after 2.5 months of using a topical finasteride/minoxidil spray and Nizoral twice a week for hair loss. The user, who started losing hair six years ago at age 22, is asked to share further progress at the six-month mark.

The user experienced reduced hair loss using grey-market KX-826 alongside Minoxidil foam, achieving better results with Minoxidil liquid but restricted to foam due to an allergy. Initial side effects included shortness of breath, racing heart, and dizziness, which subsided after the first week.

The conversation discusses hair loss linked to BDNF-increasing nootropics like Semax and Lions Mane. Suggested topical treatments include capsaicin, beta-glucan, and ginseng to counteract TGF-B activation.

A 24-year-old man is seeking advice on his current hair loss treatment, which includes 0.5mg Dutasteride daily, 2.5 mg oral Minoxidil daily, and daily low-level light laser therapy, as he's not seen improvement recently. He's also considering a hair transplant in South Korea at age 25 and is asking for opinions on this plan.

The user is sharing their progress with hair loss using finasteride, minoxidil, and nizoral. They are seeking advice on what to do next for their hair. Some suggestions include switching to dutasteride, adding microneedling, or seeking another opinion from a dermatologist.

A 35-year-old has seen no hair regrowth after 9 months using treatments including finasteride, pyrilutamide, microneedling, ketoconazole shampoo, and topical dutasteride, but experienced side effects with RU58841. Commenters suggest starting minoxidil for better results and question why it wasn't included from the beginning.

The user "macroburstmedia" is asking if adding topical minoxidil to their current treatment of oral minoxidil and finasteride can improve hair growth. Some users have shared their experiences with using both oral and topical minoxidil, while others suggest increasing the oral minoxidil dose instead.

User is experiencing hair shedding after 7 months of using finasteride 1mg daily and asks if they should continue. Their routine includes finasteride, topical minoxidil, dermarolling, and vitamins like biotin and B12.

The conclusion of the conversation is that the user has decided to embrace their hair loss and has buzzed their head. They plan to continue their current hair loss treatments until they run out of stock. They also mention having dandruff and will continue medication for that.

The user, Lofi-luu, shared their transformation from balding to having a full head of hair after getting a hair transplant and using finasteride for almost 2 years. They also discussed their workout routine and emphasized the importance of not letting balding hold them back in life.