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      community TH07 by Triple Hair entering phase III trial

      in Research/Science 1 month ago
      A new topical treatment, TH07, combining finasteride, latanoprost, and minoxidil, is entering phase III trials with promising early results. Some users express skepticism, noting the treatment uses existing products.

      community Why are there no proper phase 3 trials for RU

      in Chat  4 upvotes 1 month ago
      RU58841 lacks FDA approval due to financial and safety concerns, including potential cardiological side effects. The company abandoned further research, and users report adverse effects like heart palpitations and gynecomastia.

      community Are we still getting the PP405 phase 2a results by the end of March?

      in Research/Science  27 upvotes 2 months ago
      People are discussing the anticipated release of PP405 phase 2a results, expected by the end of March, with some skepticism about its effectiveness. There is cautious optimism due to past experiences with similar treatments like Breezula, despite concerns about the lack of presentation at the AAD 2026 conference.

      community Who else is looking forward to full phase 2 results of PP405?

      in Chat  59 upvotes 3 months ago
      PP405 is a potential hair loss treatment showing promise, especially for men with severe balding. Some are hopeful it will be a game-changer for those who cannot tolerate finasteride or minoxidil, despite skepticism about the outcomes.

      community Upcoming New Treatments - Based on Phase

      in Research/Science  63 upvotes 4 months ago
      Several new hair loss treatments are in development, with Cosmo Breezula and Kintor KX826 being the furthest along, expected to be commercialized by 2027. Veradermics is the only treatment in pill form, while others like KX/GT/Breezula will be topical.

      community Pelage are going to do two phase 3 trials for PP405. How long will it take to complete two phase 3 trials?

      in Chat  45 upvotes 4 months ago
      Pelage plans to conduct two Phase 3 trials for PP405, a new hair loss treatment, which may take about a year to complete. Users discuss various hair loss treatments, including pyrilutamide, minoxidil, finasteride, and clascoterone, with some expressing impatience over the lengthy trial process compared to faster drug approvals like the COVID vaccine.

      community I quit oral min during in shedding phase

      in Minoxidil 5 months ago
      The user stopped using oral minoxidil due to shedding and is continuing with oral finasteride and hair vitamins. They are advised that shedding is temporary and to maintain finasteride use, with examples of others successfully managing hair loss with similar treatments.

      community Petition Alert: Let's Get PP405 Phase 3 Trials in Germany by 2026!

      in Research/Science  57 upvotes 10 months ago
      A user is advocating for Phase 3 trials of the hair loss treatment PP405 to be conducted in Germany, citing benefits like a diverse patient base and faster access for European patients. Despite skepticism about the petition's influence, the user believes it can demonstrate significant interest and potentially influence strategic decisions.

      community Pelage Announces Positive Results of Phase 2a Trials for PP405

      in Update  301 upvotes 10 months ago
      PP405 shows promise in treating severe hair loss, with 31% of users experiencing over 20% hair density increase in four weeks, faster than minoxidil and finasteride. Some users are skeptical about the results' significance and long-term efficacy.

      community Thoughts on new drug PP405? Already reached phase 2

      in Research/Science  28 upvotes 11 months ago
      PP405 is a new drug in Phase 2 trials for hair loss, generating cautious optimism among users. Some users are currently using finasteride and experiencing side effects, while others are skeptical about unapproved products being sold.

      community Anyone ever get a shedding phase on RU58441

      in Chat  6 upvotes 1 year ago
      The user experienced increased hair shedding after using RU58841 for two months, but found relief from scalp itchiness. Other users shared similar shedding experiences and discussed side effects like joint pain, while also mentioning the use of finasteride and minoxidil.

      community ET-02 Now Recruiting in Texas for Phase 1

      in Research/Science  20 upvotes 1 year ago
      Eirion Therapeutics is recruiting for phase 1 of ET-02 in Texas, which showed promising hair growth results in non-clinical studies. ET-02 demonstrated significantly more hair growth compared to Minoxidil.

      community So what happened to the GT20029 phase 2 results?

      in Chat  9 upvotes 2 years ago
      The conversation is about the delay in the release of GT20029 phase 2 results by Kintor. It also mentions Minoxidil, finasteride, and RU58841 as treatments for hair loss.

      community Is this regrowth after the shedding phase?

      in Is this regrowth?  6 upvotes 2 years ago
      A user is questioning if they are experiencing hair regrowth after using minoxidil for nearly three months, along with saw palmetto, pumpkin seed oil, nizoral shampoo, and dermarolling. They are considering starting finasteride in February.

      community Follicum releases some data from previous phase 2a trial

      in Research/Science  14 upvotes 2 years ago
      Follicum discovered that their drug FOL-005 increased hair count by 12 hairs per cm2 in patients with less than 255 hairs per cm2 and is planning a phase 2b trial. They are currently fundraising for the trial, and the drug may also be effective for women.

      community Does Peppermint oil have a shedding phase?

      in Treatment  6 upvotes 3 years ago
      A user has been using peppermint oil with caffeine on their scalp and is experiencing more visible scalp, questioning if it's a shedding phase or ineffective treatment. Another person suggests the peppermint oil is not working and the user is naturally losing hair, implying that more established treatments like minoxidil or finasteride would be preferred.

      community Breezula hasn't even begun phase 3 trials yet. F*cking hell.

      in Treatment  43 upvotes 4 years ago
      The conversation is about the delay in Breezula's phase 3 trials and skepticism regarding its effectiveness compared to other treatments like RU58841 and Pyrilutamide. Some users prefer safety over effectiveness, while others express frustration with the slow progress and doubt Breezula will be a significant treatment for hair loss.

      community Can minoxidil have any effect on finasteride shedding phase?

      in Chat  13 upvotes 1 month ago
      Minoxidil and finasteride can both cause initial hair shedding, but they work differently; minoxidil promotes hair growth, while finasteride improves the hormonal environment. Starting finasteride after minoxidil may trigger additional shedding, but it often leads to improved regrowth.

      community How long are Pelage going to milk the phase 2a results of PP405?

      in Chat  21 upvotes 3 months ago
      PP405, a potential hair loss treatment, is facing delays in releasing Phase 2 results, causing frustration among users who compare it to past failed treatments. Despite skepticism, some remain hopeful about PP405's future, while others discuss alternative treatments like Clascoterone and its expected market release.