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      community Starting pyrilutamide boys wish me luck!

      in Treatment  36 upvotes 3 years ago
      A user beginning to take Pyrilutamide as a treatment for their hair loss, and other users sharing their experiences with the drug or similar treatments such as Minoxidil, Finasteride, and RU58841.

      community M 23 progress 2 Months fin and min

      in Progress Pictures  15 upvotes 1 year ago
      A 23-year-old male shares progress pictures after two months of using oral finasteride and topical minoxidil for hair loss, noting significant improvement in hair fullness and reduced scalp sensitivity. The user expresses gratitude for the dermatologist's support and the community's advice.
      FCE 28260: A Forgotten 5α-Reductase Inhibitor

      community FCE 28260: A Forgotten 5α-Reductase Inhibitor

      in Research  330 upvotes 1 year ago
      FCE 28260 (PNU 156765), an under-explored 5α-reductase inhibitor, showcases promising results in research by Giudici et al., outperforming well-known treatments like Finasteride in reducing the conversion of testosterone to DHT. Its superior efficacy, demonstrated through lower IC50 values in both natural and human recombinant enzyme studies, suggests it could offer more effective management of DHT-related conditions. Additionally, its lower molecular weight hints at better potential for topical application, potentially offering advantages in treating conditions such as androgenic alopecia. Despite its potential, it has not advanced in development, possibly due to financial limitations, leaving its therapeutic prospects and side effect profile largely unexplored.

      community 2 years on treatment (stack update)

      in Progress Pictures  461 upvotes 1 year ago
      A user shared their hair regrowth progress using Dutasteride, topical Minoxidil, Spironolactone, and Estradiol Valerate injections as part of hormone replacement therapy for transitioning. They experienced significant hair improvement and personal satisfaction but caution against this approach for non-transitioning individuals due to irreversible changes.

      community I think this is my stop, gentlepeople. So long and thanks for all the data 👋

      in Transgender  2263 upvotes 11 months ago
      A user shared their successful experience with hair regrowth and transitioning from male to female using minoxidil, finasteride, Nutrafol, microneedling, and hormone replacement therapy (HRT). They expressed gratitude for the results and encouraged others to explore treatments that align with their personal goals.

      community Why creatine and gym cause MPD

      in Finasteride/Dutasteride 3 years ago
      Gym and creatine can cause hair loss by increasing testosterone and androgenic activity. DHT blockers may help some, while others need androgen suppression with topical AA like RU or Pyri.

      community Six Month Progress Update - Hair Darker than Ever

      in Progress Pictures  164 upvotes 8 months ago
      The user experienced significant hair darkening and progress in hair regrowth over six months using 5% topical minoxidil, 5 mg oral minoxidil, 1 mg finasteride, and weekly microneedling. No side effects were reported from these treatments.

      community surprised with the progress so far

      in Progress Pictures  203 upvotes 1 month ago
      The user experienced significant hair growth and increased density after using 1.1mg finasteride for 4-5 weeks and switching from topical to oral minoxidil (3mg) for 3 weeks. They reported no shedding and were uncertain if the growth was due to the oral minoxidil or finasteride.

      community 12 years ago versus now. Pretty crazy

      in Progress Pictures  103 upvotes 2 years ago
      The user had more hair at age 39 than at 27 after using dutasteride, oral minoxidil, RU58841, and ketoconazole for over two years. Initially started with finasteride but switched to dutasteride after six months.

      community Effect of melatonin on aromatase expression

      in Update  5 upvotes 4 years ago
      Melatonin's effect on aromatase expression is unclear, with studies showing both increases and decreases. Hormonal impacts are complex and inconsistent, similar to changing health advice on other substances.

      community Massive hair gains! Hope! May this post be a light to you in dark phases when all other lights go out

      in Progress Pictures  193 upvotes 2 years ago
      A 27-year-old man saw significant hair regrowth after starting a regimen in January that included topical minoxidil with finasteride, vitamins D and B12, fish oil, zinc with magnesium, quitting smoking, and intermittent fasting. People commented on the effectiveness of minoxidil in Southern populations and asked about the details and timeline of his treatment.

      community people already noticing 2.5 months in

      in Chat  69 upvotes 1 year ago
      People noticed fuller hair after using 1mg oral finasteride, 1ml topical minoxidil daily, microneedling, and Nizoral shampoo. Users shared their experiences and were generally open about their treatments.

      community 9+ months progress pics and regimen details

      in Progress Pictures  13 upvotes 2 years ago
      The user shared a 9+ month hair loss treatment progress with 1mg finasteride in the morning, 2.5mg oral minoxidil at night, and vitamin A spray at night, noting the importance of seeing a dermatologist early as their cousin started treatment too late for it to be effective.

      community Progress but at different times?

      in Is this regrowth?  6 upvotes 2 years ago
      The user has been taking 1.25mg of oral minoxidil and 1mg of finasteride for a year and added topical minoxidil in January. They noticed hair improvement but are experiencing uneven regrowth, with the hairline improving and the middle part worsening.

      community Fin/Min/Biotin Progress Pics and symptoms

      in Progress Pictures  9 upvotes 5 months ago
      The user is experiencing progress in hair growth using 0.5mg Finasteride, 5mg Minoxidil, and 1mg Biotin daily but is also developing gynecomastia. They plan to continue the treatment for six months unless the side effects worsen.

      community Finasteride + Monxidil Update pictures.

      in Progress Pictures  263 upvotes 1 year ago
      A user shared progress pictures after using finasteride and minoxidil for two years, showing significant hair improvement. The user started treatment at age 20 and reported no side effects.

      community Dec 2024 vs now (min + fin/dut)

      in Progress Pictures  27 upvotes 7 months ago
      The user experienced hair thickening and reduced shedding using minoxidil, finasteride, and dutasteride, with a switch from finasteride to dutasteride due to ineffectiveness. They also use a saw palmetto shampoo and take vitamin D3 supplements, while considering potential underlying causes like vitamin deficiencies and hard water buildup.