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      community How is no one talking about this?

      in Treatment  6 upvotes 1 year ago
      Bovine colostrum is being discussed for its potential in hair regeneration, with some users noting that oral consumption may not be effective due to stomach acid destroying exosomes. The conversation also touches on ethical concerns about sourcing colostrum.

      community Openminded Creatine Discussion

      in Product  10 upvotes 10 months ago
      Creatine may cause hair shedding in some individuals, particularly those with genetic sensitivity to hair loss, but this is not universally experienced. Finasteride users report mixed results, with some experiencing resumed shedding when taking creatine.

      community 17M with Diffuse Thinning, Dandruff, and Body Hair Shedding

      in Basic Questions  93 upvotes 1 month ago
      A 17-year-old is experiencing diffuse thinning, dandruff, body hair shedding, and other symptoms, possibly linked to seborrheic dermatitis or telogen effluvium. They are using ketoconazole shampoo and considering blood tests to check for thyroid issues or deficiencies.

      community 2nd day on pyrilutamide - what I noticed so far

      in Treatment  7 upvotes 3 years ago
      The user started using a hair loss treatment called pyrilutamide and experienced mild chest discomfort and tightness, similar to previous side effects from RU58841. They plan to reduce the dosage due to these side effects and will provide an update on the results in 1-2 months.

      community Expectations control for SCUBE3

      in Research/Science  22 upvotes 2 years ago
      SCUBE3, a protein linked to hair growth in moles, was discovered over 25 years ago and is being developed by Amplifica for potential hair loss treatment. Concerns exist about SCUBE3's association with cancer, as it is a protein that promotes cell growth, which could potentially trigger cancer development if used for hair growth therapy.

      community Best Treatment In The Pipeline?

      in Chat  15 upvotes 2 years ago
      New treatments for AGA are emerging, including pyrilutumide, gt0029, scube3, kx-826, and pp405. Verteporfin is mentioned as a promising option.

      community Any good place to buy KX-826, AHK‑Cu and PTD-DBM?

      in Product  1 upvotes 3 months ago
      The conversation discusses purchasing experimental hair loss treatments KX-826, AHK-Cu, and PTD-DBM, with the user already using Minoxidil and having side effects from Finasteride. Concerns about the legitimacy of certain suppliers and the authenticity of products like pp405 are also mentioned.

      community The amazing fast pace of PP405.

      in Chat  327 upvotes 8 months ago
      PP405 is a new hair loss treatment advancing quickly in trials, generating excitement and skepticism about its effectiveness and marketing claims. Some see it as a potential alternative to minoxidil and finasteride, but concerns about long-term effects and the need for DHT blockers persist.

      community Why are there no proper phase 3 trials for RU

      in Chat  4 upvotes 3 months ago
      RU58841 lacks FDA approval due to financial and safety concerns, including potential cardiological side effects. The company abandoned further research, and users report adverse effects like heart palpitations and gynecomastia.

      community could this be a reason for my hair loss

      in Chat  13 upvotes 2 years ago
      The post discusses potential links between low vitamin D levels and hair loss, and how correcting this might impact the effectiveness of Minoxidil and Finasteride treatments. The responses vary, with some suggesting that vitamin D deficiency would cause overall scalp hair loss, while others believe it would first affect the most sensitive areas.

      community Spironolactone and pregnancy planning

      in Female  2 upvotes 1 year ago
      A user with AGA uses topical spironolactone 2% due to side effects from the oral form and is concerned about its use during conception and breastfeeding. They seek alternatives to prevent AGA relapse while planning pregnancy and after childbirth.

      community OND-1 "Cyclosporine A” New hair loss treatment

      in Research/Science  28 upvotes 2 months ago
      Orient Bio is developing a PLGA formulated version of Cyclosporine A to stimulate hair growth without its immunosuppressant effects. Users discuss various treatments like Clascoterone, PP405, minoxidil, and tacrolimus, expressing hope for new developments and sharing personal experiences with these treatments.

      community Clascoterone 12 months phase 3 result out

      in Treatment  45 upvotes 2 months ago
      Clascoterone is promising for hair loss, showing 24.5% improvement in satisfaction compared to placebo. Users consider it an alternative to finasteride, with concerns about absorption and side effects.

      community Finasteride does deplete important nuero-active steroids

      in Research/Science  9 upvotes 2 years ago
      Finasteride can reduce neuroactive steroids, causing side effects like depression, anxiety, and sexual dysfunction. Some users experience persistent symptoms after stopping finasteride, while others use alternative treatments like topical solutions.

      community Anyone still waiting on Pryiltamide order

      in Chat  2 upvotes 1 year ago
      The user is frustrated with the delayed delivery of their Pryiltamide order from Koshine. They mention the order was shipped on August 23 but have received no updates since.

      community My experience and a discourse on “DUPA”

      in Chat  46 upvotes 3 years ago
      How diffuse unpatterned alopecia (DUPA) is not an invitation to self-diagnose oneself with aggressive AGA and that seeking a specialized dermatologist may help people experiencing hair loss. Treatment options discussed include topical clobetasol propionate, oral minoxidil, and discontinuing finasteride.

      community FPHL vs. Mental Health: Advice Appreciated

      in Minoxidil  6 upvotes 4 years ago
      User experienced hair loss and tried various treatments, including Minoxidil, Finasteride, and Spironolactone. They face a dilemma between continuing treatments for hair regrowth and having a therapy cat, as Minoxidil is toxic to cats.

      community Nutritional factors to check for apart from DHT ?

      in Chat  11 upvotes 3 years ago
      The conversation is about identifying nutritional factors that should be checked and supplemented to address diffuse hair loss, including Vitamin D, Biotin, Vitamin C, Vitamin B, Iron, Zinc, Protein, and Omega-3. No specific treatments were mentioned.

      community For everyone buying 2-deoxy-d-ribose (2ddr)

      in Research/Science  12 upvotes 1 year ago
      The conversation discusses using 2-deoxy-d-ribose (2DDR) for hair regrowth, with users sharing mixed experiences and side effects like hair loss in new areas and increased anxiety. The original poster plans to continue testing and comparing it to minoxidil, noting potential instability in 2DDR formulations.