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      community Why are there no proper phase 3 trials for RU

      in Chat  4 upvotes 3 months ago
      RU58841 lacks FDA approval due to financial and safety concerns, including potential cardiological side effects. The company abandoned further research, and users report adverse effects like heart palpitations and gynecomastia.

      community The Big Fat Layer II

      in Research/Science  26 upvotes 5 years ago
      Hair loss treatment should target dermal white adipose tissue (DWAT) to restore hair follicles. Potential remedies include tocopherol (vitamin E), botox, rosiglitazone, niacin, kojyl cinnamate esters, and ADP355.

      community Microneedling versus Platelet-Rich Plasma

      in Research/Science  9 upvotes 8 months ago
      Microneedling and Platelet-Rich Plasma (PRP) are equally effective for treating androgenetic alopecia, with no additional benefits from PRP over microneedling. Both treatments are safe and well-tolerated.

      community It's always the Mice that gets to grow back hair.

      in Research/Science  431 upvotes 7 months ago
      Sodium dodecyl sulfate, oleic acid, and palmitoleic acid may promote hair growth, but their safety and effectiveness for humans are uncertain. Users consider trying these treatments cautiously, exploring alternatives like ostrich oil and microneedling.

      community RU58841 - How & When to Apply?

      in Product  4 upvotes 2 years ago
      RU58841 should be applied directly to the scalp, ideally once a day, a few hours before bed. Some users experienced side effects like shedding and systemic issues when using RU58841 and Minoxidil together, while others reported no side effects when using RU58841 alone.

      community Pyrilutamide - Worth it if can’t use Fin?

      in Research/Science  4 upvotes 1 year ago
      Pyrilutamide is being discussed as an alternative for those who can't use finasteride, but users report it may be ineffective at low concentrations. Some users are combining it with minoxidil, microneedling, and other treatments, but results vary.

      community HAIR REGENERATION HUMAN TRIALS with Verteporfin

      in Research/Science  13 upvotes 3 years ago
      A new human trial using an FDA-approved treatment for wound healing called Verteporfin, which may potentially be able to reverse scarring and regrow hair in that area. The trial is only lasting one month so far.

      community HairClone to start hair multiplication services in 2022

      in Update  133 upvotes 4 years ago
      HairClone plans to start hair multiplication services in 2022. Users discuss various treatments like Minoxidil, finasteride, PRP, and hair cloning, expressing both hope and skepticism about the technology and its costs.

      community Research behind RU-58642? Has anyone heard of this?

      in Research/Science  1 upvotes 1 year ago
      RU-58642 is a powerful anti-androgen that was not developed further, possibly due to safety concerns or financial reasons. RU58841 is a topical alternative, but it is less effective than finasteride and dutasteride, and its long-term effects are not well-studied.

      community FOL005 claims it's better than Finasteride and Minoxidil.

      in Technology  184 upvotes 1 year ago
      FOL-005 claims to be more effective than Minoxidil and Finasteride but lacks anti-DHT properties, leading to potential reduced efficacy over time. Concerns are raised about misleading marketing and the safety of alternative treatments like Pyrilutamide and Clascoterone.

      community Stimulating existing stem cells to grow hair.

      in Technology  119 upvotes 3 years ago
      Hair regrowth treatments, including stem cell injections, are discussed, with skepticism about their effectiveness compared to Minoxidil and finasteride. Derma stamping is mentioned as effective when used with Minoxidil, finasteride, and dutasteride.

      community Possible natural pp405 solution

      in Research/Science  45 upvotes 9 months ago
      Rotenone, a natural plant extract, may promote hair growth by increasing LDH activity and blocking MPC in the scalp, but it carries risks due to its toxicity. The suggested formulation includes Barbasco extract, DMSO, propylene glycol or PEG-400, ethanol, and a carrier oil.

      community Tressless When They See Verteporfin Results

      in Transplants  181 upvotes 2 years ago
      The conversation discusses the potential of Verteporfin, an FDA-approved drug, for hair loss treatment, particularly in combination with microneedling or PRP. Users express hope and curiosity about its application, while some remain cautious due to the need for more extensive testing.

      community Are these new follicle?

      in Finasteride  58 upvotes 1 year ago
      The user is questioning if black points on their scalp are new hair follicles. They are using finasteride and minoxidil for hair growth.

      community Anyone else just waiting until the real pyrilutamide and then GT20029?

      in Chat  5 upvotes 2 years ago
      The user is hesitant to use finasteride due to potential hormonal side effects and is waiting for the release of pyrilutamide, a new hair loss treatment. Other users suggest trying finasteride, warning about potential regret if hair loss progresses in the meantime.

      community Anyone tried topical adenosine?

      in Product  4 upvotes 3 years ago
      Hair loss discussion includes treatments like Minoxidil, Finasteride, and RU58841. User asks for opinions on topical adenosine as a treatment.

      community Promising new data on peptide serums (not sponsored)

      in Research/Science  7 upvotes 4 months ago
      Combining Minoxidil with peptide serums like Redensyl, Procapil, and Capixyl is more effective for hair growth than using Minoxidil alone, increasing hair density and thickness. However, some users are skeptical about the effectiveness of peptides, suggesting other ingredients or factors might contribute to the results.

      community Where can you find RU 588441 for cheap ?

      in Chat  2 upvotes 5 months ago
      The conversation is about finding affordable RU58841 for hair loss treatment. Suggestions include buying it in powder form and making a solution at home, with Amazon as a potential source.