New product Tomorrowlabs HSF targets hair loss through HIF pathway indirectly by removing scalp iron. Minoxidil and Stemoxydine also relate to HIF pathway.
User Tricky9555 tried various hair loss treatments for 8 months with no visible results. Others suggested considering a hair transplant, checking thyroid levels, and being patient for up to 24 months for potential results.
A user's experience with hair loss treatments, including Dutasteride, Oral Minoxidil and Finasteride; potential side effects; and the potential of using anti-androgens or microneedling.
Actor Paul Mescal, who has a receding hairline, and how it affects his success in the entertainment industry. People discussed how styling can help disguise hair loss, and that hair loss doesn't necessarily mean one's appearance is immediately ruined. Treatments such as Minoxidil and Finasteride were mentioned to combat hair loss.
A 28-year-old male experiencing hair thinning is considering minoxidil and finasteride. Minoxidil helps regrow hair, while finasteride prevents further loss; both are usually lifelong treatments.
The user has been using topical Minoxidil since April 2025 and Finasteride since September 2025, but their bald spot has worsened. They are considering switching to oral Minoxidil and have been advised to be patient, see a dermatologist, and possibly try additional treatments like derma rolling.
Pelage Pharmaceuticals is developing PP405, a topical treatment for hair growth, currently in Phase 2a trials. There is skepticism about the company's claims, and no fast-tracking approval timeline has been detailed.
A long-term finasteride user experienced side effects like sexual dysfunction, dry eyes, muscle weakness, and brain fog, which improved when they stopped the medication. They decided to stop finasteride again, questioning if maintaining hair was worth the negative impact on their well-being.
The conversation discusses potential causes of pigmentation around hair follicles, suggesting sebum buildup, autoimmune conditions, or dermatitis. Treatments mentioned include finasteride, dutasteride, and an anti-inflammatory diet, with a recommendation to consult a doctor for a proper diagnosis.
The user "Bishiop" shared a progress update on their hair density and strength after adding Minoxidil to their routine. They are also using Finasteride and microneedling. They hope to fill in their hairline by the end of the summer.
CosmeRNA, a new hair loss treatment, is expected to release soon and may become part of the "big three" treatments alongside finasteride and minoxidil. It works differently from finasteride by targeting androgen receptors in hair follicles, potentially offering fewer side effects.
The user is using topical finasteride and is considering adding minoxidil despite concerns about dependency and side effects. Another user suggests that finasteride alone can reverse hair loss, but adding minoxidil and microneedling may improve results.
Using a combination of Stemoxydine, minoxidil, dutasteride, and keto shampoo to achieve extreme hair and beard growth. The user has experienced positive results with terminal hairs at the hairline and an increase in density to their stubble after several weeks of use.
The efficacy of various hair loss treatments, including Finasteride and Dutasteride, with personal anecdotal evidence about potential side effects. It also includes advice to get a male hormone blood panel done before starting treatment, and lifestyle changes to minimize side effects.
Low-dose Dutasteride, used 2-3 times a week, is as effective as daily Finasteride for hair loss with fewer side effects. Users report increased libido and better results with Dutasteride compared to Finasteride.
The user shared a two-year hair regrowth update after using 1mg Finasteride daily and Minoxidil liquid once daily, with significant improvement and no side effects. Some users suggested adding derma rolling to the regimen, while others discussed the effectiveness of Finasteride alone before considering Minoxidil.
An update on the use of Pyrilutamide, a new drug for hair loss, which has resulted in no shedding or testicle ache; other users have questioned the science behind this and shared their own experiences with Finasteride, Minoxidil, and microneedling.
User DeadRay9 reports good progress on finasteride and ketoconazole, with irregular microneedling. They take 1.25mg finasteride, experienced increased libido, and saw improvements at 3-5 months.
The user experienced significant hair regrowth after switching from topical minoxidil to oral minoxidil and finasteride, later transitioning to dutasteride and continuing with oral minoxidil. They reported no side effects and are optimistic about further improvements.
A 23-year-old discusses their hair loss treatment using finasteride, dutasteride, oral and topical minoxidil, and topical tretinoin under medical supervision. They stress stabilizing hair loss before a hair transplant and plan to continue the regimen for at least 18 months.
Users discuss their positive experiences with finasteride for hair loss, mentioning halted hair loss, hair regrowth, and improved self-esteem. Some express satisfaction in taking action against baldness, while others note increased libido and energy.
A user's experience with finasteride and oral minoxidil for treating hair loss, which resulted in great regrowth and improved mental state. Other users asked questions about their own experiences with the treatments.
Hair loss's social impact, focusing on Will Smith defending Jada Pinkett Smith's alopecia. The conversation highlights double standards between men and women experiencing hair loss and emphasizes empathy.
Redensyl, which is a topical alternative to Minoxidil for hair loss. It may have advantages such as not making the hair greasy and lasting longer after discontinuing use than minoxidil. There are some positive reports from users, but also some negative ones, so it's unclear how effective this treatment will be in comparison to Minoxidil and other treatments like Finasteride or RU58841.
Finasteride and a hair transplant were used to reverse hair loss, leading to thicker hair and increased confidence. The user received compliments on their improved appearance.
The user plans to stop finasteride after three months, believing hair loss isn't due to DHT, and will continue with oral minoxidil, microneedling, and ketoconazole shampoo. They suspect stress and poor nutrition are the main causes and seek opinions on DHT blockers' effectiveness.
Using a dermaroller with topical minoxidil and oral finasteride regrows hair and improves temple areas. Users highlight the benefits of microneedling tools and stress the importance of consistency and proper sanitation.
The user switched from finasteride and topical minoxidil to dutasteride and oral minoxidil, experiencing some hair shedding but maintaining hair quality. Suggestions include increasing oral minoxidil dosage, considering a hair transplant, and using dermarolling, while some users recommend stopping treatment altogether.