The trial for TDM-105795 has been completed, and it was in phase 2A. The discussion seeks input on the next phases, 2B or 3, based on safety and efficacy.
New hair loss treatments like GT20029 and PP405 could potentially replace minoxidil and finasteride, offering better results with fewer side effects. However, current treatments like finasteride and minoxidil are still effective for many, despite concerns about side effects.
The user is seeking advice for the best topical treatment to combat their ongoing hair loss, despite already using oral dutasteride, RU-58841, and minoxidil. They are considering adding CB-03-01 or topical Spiro to their regimen to lower testosterone levels at the follicles.
User is excited about hair regrowth progress after 3 months using finasteride, minoxidil, dermarolling, and biotin. Initial side effects included chest tightness and faster heartbeat, but none persist.
Veradermics' oral minoxidil shows promise for hair regrowth, with some users reporting significant improvements, while Pelage's PP405 results are less convincing and lack transparency. There is skepticism about both treatments' long-term effectiveness and potential side effects.
So maybe vitamin D is important here
This conversation discussed the user's successful results from a combination of treatments, including finasteride, minoxidil, ketozolin shampoo, Vitamin D and biotin. The discussion also included advice about frequency and dosages for these treatments.
Various hair growth treatments were discussed, including microneedling, bimatoprost, setipiprant, stemoxydine, PGE2, CB-03-01, WNT Beta-Catenin upregulators, KY19382, topical estrogen, IGF-1, GH, MK-677, oral castor oil, fisetin, resveratrol, cetrizine, and lactic acid. Users shared experiences and sources for these treatments, with some expressing interest in topical solutions and others noting the lack of FDA approval or scientific evidence for certain options.
A 27-year-old male experiencing hair loss at Norwood 3 level has tried minoxidil and finasteride but stopped finasteride due to side effects. He is exploring alternatives like Dermapen, Regenepure DR Shampoo, saw palmetto, and considering aromatase inhibitors for managing side effects, while also seeking advice on DHT blockers.
The conversation discusses why CB-03-01, a potential hair loss treatment, isn't widely discussed despite evidence of its effectiveness and safety. Some users mention other treatments like melatonin, procianidin b2, and RU58841, debating their effectiveness and safety.
A user shared 3-month progress pictures using 1mg finasteride daily, reporting no side effects and planning to add oral minoxidil. Replies praised the results and questioned the need to add minoxidil.
The user experienced hair regrowth using finasteride, biotin, folic acid, vitamin D3, and microneedling, despite initial shedding. Vitamin D3 deficiency caused hair loss and insomnia.
Hair loss treatments like Breezula and PP405 are delayed, with approvals taking years, while existing treatments like minoxidil and finasteride remain popular. New treatments like Clascoterone and Veradermics are in trials, but high costs and lengthy approval processes slow their release.
A user is using minoxidil for hair loss and considering adding finasteride but their dermatologist advised waiting to see if minoxidil works alone. They are thinking about taking saw palmetto (serenoa repens) and biotin as alternatives and are asking for others' experiences and potential side effects.
PP405 is likely a scam, with concerns about its legitimacy and safety, as it may cause unintended tissue growth. Users suggest sticking to known treatments like finasteride and minoxidil.
The conversation is about a user's 3-month hair loss treatment using topical minoxidil, oral finasteride, a derma roller, ketoconazole shampoo, rosemary oil, and vitamin D supplements, alongside weight loss. Users discuss shedding, vitamin D benefits, and reducing sugar intake.
User reports 3-month progress using Fin 0.5mg/day, 1x minox 5%, keto shampoo every 3 days, and microneedling 1.5mm a week. Others suggest shaving sides or trying shaved head look, while some discuss side effects and dosages.
GT20029 and KX826 are promising hair loss treatments, with GT20029 increasing hair count and KX826 showing significant results. KX826 may be a good alternative for those who can't use finasteride or dutasteride, though results vary.
A South Korean company, Therazyne, has developed a promising hair loss treatment using a WNT chain surrogate that binds to Frizzled 7, with human follicle testing expected soon. Current treatments like minoxidil and finasteride are not seen as cures, and while optimism exists for future solutions like PP405, approval processes are lengthy.
Researching the effectiveness of the hair loss treatment Pyril in comparison to other treatments such as Minoxidil, Finasteride, and RU58841. Replies suggest that users often fail to provide updates on their experience with Pyril.
A 19-year-old male shared his 3-month hair regrowth progress using finasteride, minoxidil, and microneedling, with noticeable improvement. He uses 1mg oral finasteride daily, 5% minoxidil foam twice a day after day 80, and microneedles with a 1.5mm derma stamp every 1-2 weeks.
Pyrilutamide from RUdirect is discussed, with users sharing experiences and alternative sources like Koshinemall. Users mention using treatments like minoxidil, RU58841, and dutasteride for hair loss.
CRISPR treatments for blood disorders have been approved, leading to discussions about its potential for treating hair loss (AGA). A study showed that editing a gene related to DHT sensitivity could lead to hair regrowth, suggesting CRISPR may eventually be used for AGA, but it's expected to be expensive and not soon available.
A treatment containing Wnt and Follistatin was found to be safe and effective for hair regrowth in a Phase 1 clinical trial. Specific treatments discussed include Minoxidil, Finasteride, and RU58841.
GentleIris stopped hormone-induced hair loss with diet changes but couldn't regrow lost hair. A reply suggested microneedling instead of Platelet-Rich Plasma Therapy (PRP) for hair regrowth.
User shared a 3-month update on using finasteride and vitamins (Zinc, D3, B12, Magnesium) for hair loss. Progress pictures show improvement, and other users commented on their experiences and asked about specific vitamins.
Female with PCOS experiences receding and thinning hair, wants dutasteride instead of spironolactone. Discusses desire to reduce DHT without losing libido.
The user shared a 3-month progress update on hair loss treatment using oral finasteride, oral minoxidil, dutasteride, ketoconazole, biotin, collagen shampoo, dermarolling, and scalp massage, noting some side effects like decreased libido and low mood. The user received feedback and questions about their regimen, including why both finasteride and dutasteride are used.
Tretinoin may help more minoxidil convert to its active form and could potentially increase its absorption, raising concerns about safety if too much enters the bloodstream. It's unclear if tretinoin affects finasteride absorption.
FOL-005 claims to be more effective than Minoxidil and Finasteride but lacks anti-DHT properties, leading to potential reduced efficacy over time. Concerns are raised about misleading marketing and the safety of alternative treatments like Pyrilutamide and Clascoterone.