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      community GT20029 China Phase II Trial For AGA Reached Primary Endpoint

      in Research/Science  133 upvotes 2 years ago
      The GT20029 tincture, a topical androgen receptor degrader, showed significant hair growth and good safety in a China Phase II trial for male androgenetic alopecia (AGA), with the 1% dose twice weekly identified as optimal. The company plans to initiate Phase III trials in China and Phase II in the U.S., and the treatment also shows promise for acne.

      community How is verteporfin doing in trials?

      in Chat  9 upvotes 2 years ago
      The conversation is about the progress of verteporfin in hair loss trials, with users expressing curiosity about its effectiveness and updates. Specific treatments mentioned include FUE (Follicular Unit Extraction) combined with verteporfin, with one reported case of donor area regrowth after a year, and three patients being monitored post-treatment by Dr. Bloxham with monthly updates on YouTube.

      community 3 months in - I feel optimistic

      in Is this regrowth?  115 upvotes 1 year ago
      The user is optimistic about hair regrowth after 3 months of using 1mg oral finasteride daily, topical minoxidil twice daily, and microneedling once a week. They report improvements in hair density and color, particularly at the crown and fringe.

      community I feel so discouraged. It’s month 3 of microneedling and I see nothing.

      in Microneedling  6 upvotes 7 months ago
      The user feels discouraged after three months of microneedling with no visible hair regrowth, despite using 5% topical minoxidil and 200mg of spironolactone. Others suggest waiting 12 months for results, checking vitamin D levels, and considering tretinoin or tazarotene cream instead of microneedling.

      community Mixing topical solutions: Morr F 10% and Loreal Seryoxil

      in Treatment  2 upvotes 2 months ago
      Mixing topical solutions like Morr F 10% (Minoxidil) and L'Oreal Seryoxyl (Stemoxydine) before application may not reduce their effectiveness. The goal is to apply treatments all at once instead of multiple times a day.

      community How long have you tried topical melatonin?

      in Treatment  4 upvotes 2 years ago
      The conversation is about the effectiveness of topical melatonin for hair loss, asking for details on dosage, frequency, duration of use, results, and brand information. An update includes a skeptical view on the studies regarding melatonin's effectiveness.

      community Seeking Advice on Tretinoin Strength for Minoxidil Success at Age 30

      in Basic Questions  190 upvotes 1 month ago
      The user is considering adjusting tretinoin strength to enhance minoxidil effectiveness, questioning whether to use 0.025% or 0.01% instead of 0.05% due to increased hair shedding. They have been using finasteride, minoxidil, and Nizoral, and are contemplating reintroducing microneedling.

      community 6 months progress no fin 27m topical foam minox

      in Progress Pictures  250 upvotes 2 years ago
      The user has been using 5% Minoxidil foam twice daily, microneedling every two weeks, and Nizoral 2% shampoo weekly for hair loss treatment. They've seen improvements in their hairline and eyelashes, and are considering adding finasteride to their regimen.

      community 30 Female, a month into 5% Minoxidil - is this normal?

      in Female  30 upvotes 1 year ago
      A 30-year-old woman experiencing rapid hair loss is using 5% Minoxidil, Saw Palmetto, vitamins, and Nizoral, but is advised to see a dermatologist as her symptoms may indicate a condition other than androgenetic alopecia, such as alopecia areata or a thyroid issue. Many suggest a biopsy and blood tests to determine the underlying cause.

      community 0.25 % fin and 0.25% dut together topically

      in Treatment  3 upvotes 5 months ago
      The user is dissatisfied with the results of using 0.3% finasteride and 6% minoxidil for hair thinning and is considering a topical treatment combining finasteride, dutasteride, minoxidil, melatonin, caffeine, and latanoprost. Another user suggests that high topical concentrations can lead to systemic exposure and recommends using oral dutasteride and microdosing topical finasteride.

      community 3 month update, topical Min/Fin

      in Progress Pictures  15 upvotes 1 year ago
      A 39-year-old has been using topical 5% minoxidil for 11 years, added microneedling, and recently started using a topical combination of minoxidil and 0.3% finasteride, noticing some hair regrowth after three months. They experienced minor side effects when switching finasteride concentrations and plan to continue the treatment, possibly adding oral finasteride or dutasteride if significant progress is seen after a year.

      community 3 months and a half on topicals

      in Is this regrowth?  30 upvotes 1 year ago
      The user experienced significant hair regrowth after 3.5 months using a topical 2-in-1 from Hims, ketoconazole, and weekly microneedling. The user is 37 years old.

      community 3.5 months progress - hairline

      in Progress Pictures  88 upvotes 2 years ago
      The user stopped using topical minoxidil and finasteride after 2.5 months and switched to oral finasteride, 1mg daily, and did microneedling 1.5mm seven times. They experienced occasional sleep issues and watery semen as side effects, which stopped after discontinuing the topical treatment.

      community Progress but at different times?

      in Is this regrowth?  6 upvotes 2 years ago
      The user has been taking 1.25mg of oral minoxidil and 1mg of finasteride for a year and added topical minoxidil in January. They noticed hair improvement but are experiencing uneven regrowth, with the hairline improving and the middle part worsening.