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      community Summary of Procapil video by Haircafe

      in Minoxidil  2 upvotes 9 months ago
      Procapil is marketed as a natural hair loss treatment but lacks strong evidence and is industry-biased. Minoxidil and Finasteride are the only FDA-approved treatments for androgenetic alopecia.

      community Figuring out my own experimental protocol

      in Treatment  10 upvotes 2 years ago
      User tries dermapen for hair loss and plans to use non-mainstream topicals like c60, ghk-cu, and ptd-dbm with valproic acid. They also use a head massager and modified LLLT belt for additional treatment.

      community Welp - pp405 conference showed nothing

      in Update  79 upvotes 2 weeks ago
      PP405 shows potential for hair growth by increasing terminal hair and converting vellus hairs, but results are modest and more waiting is needed. It complements existing treatments like minoxidil and finasteride, but won't replace them.

      community Is there any new drug that looks promising ?

      in Research/Science  25 upvotes 2 years ago
      The conversation discusses GT20029, a drug in Phase II trials that targets androgen receptors with minimal systemic effects, and TDM-105795, a growth stimulant with a different mechanism than minoxidil that may revive papilla stem cells. Both are potential new treatments for hair loss.

      community Pyrilutamide from Hairlisciously? Other suppliers?

      in Treatment  8 upvotes 3 years ago
      The conversation is about the effectiveness and trustworthiness of Pyrilutamide hair loss treatment sold by Hairlisciously, with concerns about product purity and a request for alternative suppliers. No specific treatments were confirmed to be used by participants.

      community PP405 timeframe ? Could it replace current treatments ?

      in Update  34 upvotes 9 months ago
      PP405 is a potential new hair loss treatment that might replace finasteride and minoxidil, but it is still in clinical trials and may not be available until 2028-2031. There is skepticism about its effectiveness, with only a 20% increase in hair density observed in some participants.

      community Reducing Fibrosis in Hair Loss: Topical Pirfenidone

      in Research/Science  55 upvotes 2 weeks ago
      Topical pirfenidone is highlighted as an effective anti-inflammatory and anti-fibrotic treatment for hair loss, particularly in addressing perifollicular fibrosis, which may enhance the effectiveness of standard treatments like finasteride and minoxidil. The user also uses calcipotriol, MCT oil, ciclopirox shampoo, and benzoyl peroxide shampoo as part of their regimen.

      community My personal experience/observations fighting AGA seriously for 5 years

      in Treatment  47 upvotes 1 year ago
      Minoxidil with alcohol and propylene glycol was more effective than non-alcohol versions, and RU58841 worked best in a non-water-based solution. Oral finasteride showed better results than topical, despite side effects; microneedling and tretinoin worsened hair loss, and PRP was only helpful when younger.

      community Don't use PP405 from everychem. it is likely fake.

      in Research/Science  66 upvotes 9 months ago
      PP405 from Everychem is likely fake and potentially harmful, with concerns about its stability and the risk of using the wrong MPC inhibitor, which could damage hair follicles. The real PP405 was studied under strict conditions, and DIY attempts are discouraged due to unknown formulation and quality control.

      community Hair follicle neogenesis

       5 upvotes 10 years ago
      A user plans to experiment with creating new hair follicles using methods like derma rolling, applying lithium chloride, tannic acid, and various other substances including caffeine, ketoconazole, and raspberry ketones. They also consider using anti-inflammatories, immunosuppressants, and DHT inhibitors to potentially improve results.

      community If PP405 works it will be fkn impossible to buy it.

      in Technology  104 upvotes 5 months ago
      PP405 is a potential hair loss treatment that may activate dormant hair follicles, but there are concerns about its effectiveness, cost, and side effects. Users discuss treatments like minoxidil, finasteride, and RU58841, expressing skepticism about PP405's long-term success and accessibility.

      community hmi115 is coming. Prepare yourselves for what's coming

      in Technology  106 upvotes 2 years ago
      The conversation discusses HMI-115, a potential cure for hair loss. Users share mixed opinions, with some expressing skepticism and others sharing anecdotal evidence of its effectiveness, including photos of significant hair regrowth from a trial participant.

      community Whats up with Prolactine these days?

      in Research/Science  20 upvotes 3 years ago
      The conversation discusses the potential role of prolactin in hair loss and mentions treatments like HMI115, mucuna pruriens, Zinc, and B6 P5P for lowering prolactin levels. It also touches on the use of natural compounds and the lack of studies due to funding issues.

      community Pp405 - it has to work. It has to.

      in Research/Science  170 upvotes 1 month ago
      Hair loss treatments, including PP405, minoxidil, finasteride, and RU58841, with hopes for future solutions. Participants discuss the emotional impact of hair loss and consider alternatives like hair transplants or acceptance.

      community FOR PYRILUTAMIDE NON-BELIEVERS (progress album, 14 months)

      in Progress Pictures  30 upvotes 2 years ago
      A user shared their 14-month progress using Pyrilutamide and Minoxidil for hair loss, noting improvement and no side effects with these treatments, unlike their negative experiences with Finasteride and RU58841. They emphasized the importance of consistent application for seeing results.

      community RU58841 vehicle penetration (Study for minoxidil)

      in Treatment  12 upvotes 2 years ago
      The user mixes their own RU58841 solution and found that increasing the ethanol content improved absorption and reduced scalp itching. A study on minoxidil showed that penetration increased with higher ethanol concentrations, reaching maximum penetration at 90% ethanol.

      community What are the chances of being chosen for PP405 trials?

      in Research/Science  3 upvotes 2 months ago
      The conversation discusses the potential benefits and risks of participating in the PP405 hair loss trials, emphasizing that those using Minoxidil or finasteride are less likely to be accepted. Participants are interested in the trial as it offers hope for effective treatment without the side effects associated with current medications.

      community Oral Castor Oil Experiment Day #1

      in Minoxidil  8 upvotes 3 years ago
      The user is experimenting with taking 1-1.5ml of pure castor oil orally daily as an alternative to minoxidil for hair growth. They aim to find a safer option that promotes overall body and head hair growth without the side effects of minoxidil.