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      community My hairloss stack, progress pics soon maybe for 1 year RU

      in Technology  49 upvotes 3 years ago
      The conversation is about a user's hair loss treatment routine, which includes RU58841 for 9 months and Dutasteride for 6 months, with other unspecified treatments considered extra. One user inquired about the source of RU58841.

      community Found an interesting little article

      in Research/Science  5 upvotes 1 year ago
      A new painless microneedle patch shows promise in reversing hair loss. The discussion focuses on potential new treatments beyond common options like Minoxidil, finasteride, and RU58841.

      community Forgotten Hair Loss Peptide by L'Oreal: KPV

      in Research/Science  4 upvotes 1 year ago
      KPV, a peptide patented by L'Oreal, may promote hair growth and reduce hair loss by extending the anagen phase and has anti-inflammatory properties. It could be combined with treatments like minoxidil for enhanced effects.

      community Still receding at 8 months on finasteride?

      in Finasteride/Dutasteride  21 upvotes 10 months ago
      The user has been using oral finasteride, oral minoxidil, topical minoxidil, and microneedling to address hair loss but continues to experience recession after 8 months. Suggestions include being patient as treatments can take 12-18 months to show effects, considering a switch to dutasteride, and consulting a dermatologist for potential underlying scalp conditions.

      community Anyone use hair fiber products like Toppik?

      in Question  21 upvotes 6 years ago
      User phoenixblue asked about hair fiber products like Toppik and if they cause hair loss by clogging pores. Replies suggested that Toppik is safe, but effectiveness varies; some users experienced no hair loss, while others had issues with color or sweating.

      community 1mg Finasteride 4 week Progress

      in Progress Pictures  23 upvotes 2 years ago
      The conversation is about hair regrowth progress after 4 weeks of using 1mg Finasteride, with the user experiencing initial shedding followed by the appearance of small dark hairs on the scalp. Specific treatment mentioned is 1mg Finasteride.

      community Topical finasteride in liposomal formulation

      in Finasteride  5 upvotes 6 years ago
      Topical finasteride in a liposomal formulation reduces systemic absorption compared to ethanol solutions. The user is seeking sources for such products, noting that popular options like morr-f are not liposomal.

      community 8 months Oral min and Dutasteride

      in Progress Pictures  62 upvotes 1 year ago
      Oral minoxidil and dutasteride are used for hair loss with mixed results. Some users report new growth, while others suggest scalp inflammation may be an issue.

      community Using Maneup Instead of Minoxidil

      in Progress Pictures  103 upvotes 1 year ago
      A 51-year-old woman switched from Minoxidil to Maneup, a copper peptide treatment, experiencing initial hair loss but later regrowth with different hair texture. Users debated Maneup's effectiveness, with some considering it alongside finasteride.

      community Highly experimental stack! Self Study Coming!

      in Research/Science  4 upvotes 2 months ago
      A 19-year-old plans to use an experimental hair loss treatment stack including micro-needling, Minoxidil, Pyrilutamide, Ketoconazole shampoo, and other unreleased compounds like PP405. Users advise against using unverified treatments and suggest sticking to proven options like Finasteride, with some recommending topical application to avoid side effects.

      community New Hair Loss Cure: AMP-303 Is Back. It’s what PP405 should have been.

      in Research/Science  5 upvotes 2 months ago
      AMP-303 and AMP-601 are new hair loss treatments targeting dermal papilla cells, with AMP-303 showing early efficacy in transitioning vellus hairs to terminal hairs after one injection. Further clinical trials are planned, and these treatments are seen as promising due to their biologic approach and less frequent application compared to daily treatments.

      community PP405 2a study was a safety study. Some rational explaining.

      in Research/Science  22 upvotes 9 months ago
      The conversation discusses the safety study of PP405, emphasizing that early trials focus on safety rather than efficacy, and that any efficacy data from such a short study should be viewed skeptically. It also highlights that the information released is primarily for securing funding, and that meaningful efficacy results are expected in later phases.

      community 7 month progress on topical fin/min

      in Is this regrowth?  18 upvotes 2 years ago
      After 7 months of using topical finasteride/minoxidil, microneedling, and Nizoral shampoo, the user believes they are seeing hair regrowth. They are seeking further advice to improve their results, excluding hair transplant options.

      community RU58841 - How & When to Apply?

      in Product  4 upvotes 2 years ago
      RU58841 should be applied directly to the scalp, ideally once a day, a few hours before bed. Some users experienced side effects like shedding and systemic issues when using RU58841 and Minoxidil together, while others reported no side effects when using RU58841 alone.

      community When could we expect pp405 to hit the market?

      in Research/Science  31 upvotes 1 year ago
      PP405 is expected to finish Phase 2 trials in late 2025, with potential market availability around 2028-2029 if all goes well. Current treatments like finasteride and minoxidil are still popular, while new options like KX-826 and Breezula are anticipated soon.

      community Unofficial Dermapen/Roller Guide

      in Treatment  254 upvotes 7 years ago
      Treatments for hair loss, including microneedling (dermarolling and dermapen) and the use of minoxidil, finasteride, and RU58841. It provides detailed information about cost and usage of the various treatments, as well as potential side effects.

      community Kintor Pharmaceutical Announces AR-PROTAC (GT20029) Approved for Acne and Androgenic Alopecia Clinical Trials in China

      in Technology  13 upvotes 5 years ago
      The conversation discusses the approval of Kintor Pharmaceutical's AR-PROTAC (GT20029) for clinical trials in China for acne and androgenic alopecia. One user expresses optimism about new treatments being developed and seeks clarification on how the new drug works, specifically if it temporarily degrades the AR protein to reduce DHT sensitivity in hair follicles.

      community Are we underestimating systemic absorption with homemade/generic Topical Fin? (HPCH vs. PG/Ethanol formulations)

      in Research/Science  5 upvotes 4 months ago
      Topical finasteride may have higher systemic absorption and lower efficacy when using a Propylene Glycol/Ethanol formulation compared to the hydroxypropyl chitosan (HPCH) formulation. The safety profile of topical finasteride relies heavily on the HPCH formulation, and using standard solutions might lead to different pharmacokinetics.

      community Hair Loss Treatment Iceberg Chart

      in Satire  1378 upvotes 4 years ago
      Hair loss treatments discussed include Minoxidil, Finasteride, RU58841, ass hair transplant, topical Viagra, castration, and transitioning to female. A user mentions an experimental drug called M4U-5 (Mousteride) that turns you into a mouse.