Search

for
Search:

GlossaryPinacidil

Pinacidil is a potassium channel opener that has been studied for its potential role in promoting hair growth and treating hair loss. It works by enhancing blood flow to hair follicles and may stimulate hair regrowth by prolonging the anagen (growth) phase of the hair cycle. Unlike other hair loss treatments, pinacidil is not a topical minoxidil derivative but shares similar mechanisms in promoting vasodilation and improving follicular health. Its relevance lies in its potential as an alternative or adjunct therapy for conditions like androgenetic alopecia.

Related Terms

Sort by

Community Join

30 / 1000+ results

community REVOLUTION in AUGUST: New possibilities according to Dr. Muñoz (pinacidil, cromakalim, diazoxide and nicorandil)

in Technology 14 upvotes 6 months ago

Dr. Muñoz's discovery suggests that targeting potassium channels in fibroblasts could reactivate hair growth, offering new treatment possibilities for alopecia. Potential strategies include using minoxidil, diazoxide, and other potassium channel openers, as well as bioelectric devices and direct growth factor applications.

community Creatine is the opposite of minoxidil !

in Research/Science 321 upvotes 5 months ago

Creatine may counteract minoxidil's hair growth effects by closing potassium ATP channels, potentially leading to hair loss in predisposed individuals. Despite anecdotal reports, there is no conclusive evidence linking creatine to hair loss.

community P-1075: a BETTER version of Minoxidil

in Research/Science 6 months ago

P-1075 is a more potent hair growth agent than Minoxidil, but it poses significant heart risks, making it unsafe for use. Despite promising results in macaques, concerns about its cardiotoxicity in rats have halted its development.

community Sustaining minoxidil dependent hairs?

in Research/Science 9 upvotes 1 year ago

Minoxidil-dependent hairs fall out if minoxidil is stopped. New treatments like GT20029, FOL055, or TDM105795 might help sustain these hairs.

community 28M experiencing thinning - first timer here, please help

in Treatments 370 upvotes 4 months ago

A 28-year-old male experiencing hair thinning is considering minoxidil and finasteride. Minoxidil helps regrow hair, while finasteride prevents further loss; both are usually lifelong treatments.

community Pyrilutamide is available at Minoxidilmax

in Research/Science 60 upvotes 3 years ago

Minoxidilmax offering a 0.5% Pyrilutamide solution and debating the cost, effectiveness, and safety of using it alone or with other treatments such as Finasteride and Minoxidil.

community PYRILUTAMIDE PHASE 3 RESULTS : No statistical significance

in Research/Science 126 upvotes 2 years ago

The phase 3 trial results for Pyrilutamide showed no significant difference from the control treatment in increasing hair count, leading to the company halting its development. Users discussed their disappointment and skepticism about hair loss treatments, with some mentioning other treatments like Minoxidil, Finasteride, and RU58841.

community Any experiences with pyrrolidinyl diaminopyrmidine oxide (marketed as triaminodil, nanoxidil, vividine, but NOT aminexil/kopexil, it's something different) when compared to minoxidil?

in Minoxidil 1 upvotes 3 years ago

The conversation discusses the use of pyrrolidinyl diaminopyrmidine oxide (triaminodil) compared to minoxidil for hair loss treatment. The user is considering switching from 5% minoxidil to a product containing 5% triaminodil.

community Pyrilutamide - Worth it if can’t use Fin?

in Research/Science 5 upvotes 10 months ago

Pyrilutamide is being discussed as an alternative for those who can't use finasteride, but users report it may be ineffective at low concentrations. Some users are combining it with minoxidil, microneedling, and other treatments, but results vary.

community Fluridil solution at Actifolic

in Treatment 5 upvotes 3 years ago

Fluridil, also known as Topilutamide or Eucapil, is discussed as a treatment for hair loss. It is noted as an androgen receptor antagonist, not a vasodilator.

community Pyrilutamide available at Actifolic now

in Research/Science 15 upvotes 3 years ago

Pyrilutamide, a new hair loss product with the potential to be more effective than RU58841 and safer than CB, but expensive.

community pyrilutamide phase 2 results right here, thanks to user Glaringbooch

in Chat 45 upvotes 3 years ago

Pyrilutamide, a new drug being tested to combat hair loss that has been found to perform comparably or better than finasteride and dutasteride in the initial 6 months of treatment with minimal reported side effects.

community What happened to Pyrilutamide?

in Technology 1 upvotes 1 year ago

Pyrilutamide's 0.5% solution showed minimal improvement, while the 1% solution appears more promising but costly. The user is currently using finasteride and oral minoxidil and considering adding Pyrilutamide if effective and affordable.

community A Technical Question About Pyrilutamide

in Research/Science 5 upvotes 2 years ago

Pyrilutamide is believed to be more effective than RU58841 and 1 mg finasteride in treating hair loss, with no systemic hormonal effects and the potential to block more than 31% of scalp DHT. It may also antagonize scalp testosterone due to its action as an androgen receptor antagonist.

community What’s the update on Pyrilutamide?

in Chat 12 upvotes 3 years ago

Pyrilutamide is seen as a last hope for those who can't take finasteride, with promising results reported. However, there's uncertainty about the quality and consistency of Pyrilutamide from black market sources.

community Alpicort E: Diffuse thinning/MPB medication, Can't find much info on it?

in Treatment 2 upvotes 2 years ago

A user was prescribed Alpicort E, which contains Estradiol Benzoate, Prednisone, and Salicylic Acid, for hair loss and is seeking others' experiences due to concerns about potential side effects.

community Finally about to start Pyriltamide (ONLY Pyriltamide)

in Chat 63 upvotes 1 year ago

A user is excited to start using Pyriltamide for hair loss after experiencing side effects from topical finasteride. Other users discuss the potential and skepticism of Pyriltamide compared to older treatments like finasteride and RU58841.

community Starting Pyrilutimide 5% Update

in Treatment 1 upvotes 2 years ago

The user started using Pyrilutamide 5% for hair loss and has not experienced side effects after two days. They previously had side effects from Fluridil and topical Minoxidil 5%, and their hair continued thinning with topical Spironolactone.

community discouraged about pyrilutamide

in Research/Science 11 upvotes 3 years ago

Discouragement regarding Pyrilutamide, a drug in development for hair loss, and the potential side effects of Finasteride. People discussed anecdotal experiences with Pyrilutamide as well as suggestions to wait out Phase 3 trials before making any conclusions.

community My experience with Pyrilutamide

in Update 3 upvotes 2 years ago

The user experienced a slight decrease in hair shedding and scalp itch, and reduced sebum production using Pyrilutamide, but stopped due to chest pain, breathing difficulties, and heart issues. They felt normal a week after discontinuing and doubted FDA approval for the drug.

community This sub trying to get its hands on Pyrilutamide in light of the recent results

in Satire 21 upvotes 3 years ago

Hair loss treatments including Minoxidil, Finasteride and RU58841; with a focus on Pyrilutamide could potentially be used as an effective treatment.

community pyrilutamide – did anybody had any success on it?

in Finasteride/Dutasteride 15 upvotes 3 years ago

Potential success with the hair loss treatment Pyrilutamide, and possible group buying opportunities for it along with other treatments such as Finasteride and Minoxidil.

community PP405 Drug in Action: Picture From Official Company Website

in Technology 776 upvotes 1 year ago

PP405 shows promise for hair follicle reactivation with minimal side effects. Users recommend continuing Minoxidil and Finasteride until more results are confirmed.

community Potentially Positive Pyrilutamide News Coming

in Research/Science 6 upvotes 1 month ago

Kintor Pharmaceutical's stock rise suggests potential positive news about Pyrilutamide, a topical anti-androgen. GT20029 may also compete with existing treatments like finasteride and dutasteride.

community pyrilutamide solution progress log

in Product 20 upvotes 3 years ago

A 28 year old using a hair loss prevention protocol to restore thinning hair, which includes finasteride, dutasteride, minoxidil, stemoxydine, alopecin, nizoral shampoo and microneedling; the user is now adding pyrilutamide solution to the regimen with the hope of improving their results. RU58841 was also ordered but not yet used.

community What's your thoughts on Pyrilutamide

in Product 6 upvotes 4 months ago

The conversation is about using pyrilutamide and RU58841 as topical solutions to prevent hair loss. Pyrilutamide is considered safer but less potent than RU58841, which some users find effective despite potential side effects like heart palpitations.

community why is procapil not preferred ?

in Product 1 year ago

Minoxidil is commonly used for male pattern baldness, but Procapil is considered to have fewer side effects and be more effective. The user seeks information or experiences regarding Procapil.

community Swapping from Fluridil to Pyrilutimide?

in Treatment 1 upvotes 2 months ago

The conversation discusses hair loss treatments, with the main focus on using Fluridil and considering switching to Pyrilutamide. Other treatments mentioned include minoxidil, topical finasteride, nizoral shampoo, and saw palmetto supplements, with advice to stick with Fluridil for at least six months before considering alternatives.

community pyrilutamide GB update please? Anything no matter how big or small

in Update 33 upvotes 3 years ago

The effects of Finasteride on hair loss and its side-effects, such as aching balls. The user has been taking it for two years with no changes to the symptom.

community Just noticed that Pyrilutamide no longer sold by anageninc (and my experience)

in Update 6 upvotes 3 years ago

User Solid_Repeat5382 shared their experience with Pyrilutamide for hair loss, which initially reduced shedding but later lost effectiveness. They plan to switch back to RU58841 and finasteride, while continuing minoxidil and dermapen treatments.