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      community blood DHT levels shot up after doubling dutasteride dosage

      in Finasteride/Dutasteride  20 upvotes 1 year ago
      A user increased their dutasteride dosage from 0.5mg to 1mg daily, resulting in a rise in DHT levels from 148 pg/mL to 281 pg/mL, and is considering switching back to finasteride due to continued hair loss. Replies suggest retesting and emphasize the importance of bloodwork before starting treatments.

      community People's personal thoughts on my treatment.

      in Treatment  8 upvotes 2 years ago
      A 20-year-old with stage 3 hair loss saw good results using Topical Min 5%, Oral Fin 1mg, DHT Blocker Shampoo, and DHT blocking and Vitamin gummy. The doctor advised stopping Fin after six months due to hormone concerns, but the user is hesitant.

      community CB-03-01: I need help

      in Treatment  7 upvotes 5 years ago
      The user stopped using finasteride and RU58841 and is considering CB-03-01 for androgenic alopecia but is concerned about the cost and effectiveness, especially at a lower dose than in clinical trials. They are also using minoxidil, micro-needling, and nizoral shampoo but are unsure about the correct application method for CB-03-01.

      community Dependency on Minoxidil - what to do?

      in Transgender  1 upvotes 2 years ago
      The individual is using oral minoxidil and finasteride to treat androgenetic alopecia with good results but is considering stopping due to concerns about long-term effects on the heart and potential hair dependency on the medication. They are also contemplating the impact of hair loss on gender dysphoria and considering the use of wigs as an alternative.

      community 5-month finasteride - diffuse thinning update

      in Progress Pictures  27 upvotes 1 year ago
      The user shared a 5-month update on using finasteride, minoxidil, and ketoconazole shampoo for diffuse thinning, along with supplements like B-Vitamins, D-Vitamins, Iron, and Beta carotene. They noted improvement in hair condition and encouraged others to check previous posts for more information.

      community Telogen Effuvium from crash diet recovery help.

       1 upvotes 9 years ago
      A person experienced hair loss due to a crash diet and is now seeking advice on recovery, including dietary changes and potential treatments like biotin and pumpkin seed oil. They are concerned about nutrient deficiencies and considering a dermatologist visit for further guidance.

      community Going to inject NAD+ and GHL-Cu into Scalp for a few months

      in Chat  1 upvotes 7 months ago
      The conversation discusses a user's plan to inject NAD+ and GHK-Cu into their scalp to improve hair health, with concerns raised about the risks of infection and necrosis. Alternatives like finasteride, dutasteride, microneedling, oral minoxidil, and scalp massages are suggested.

      community having hair loss as a teen SUCKS. A LOT.

      in Female  12 upvotes 3 years ago
      A teenage girl who has been diagnosed with ADA and is struggling with hair loss, which has caused her to lose confidence. She is looking for recommendations on treatments such as finasteride or Minoxidil, and lifestyle advice including vitamins and other supplements that might help with the issue.

      community What about cofactor NADPH ? Why don't we ever talk about it ?

      in Research/Science  11 upvotes 2 years ago
      The conversation discusses the role of NADPH in hair loss and the potential impact of creatine and B complex vitamins on hair shedding. The user theorizes that increasing NAD levels with B complex vitamins may reduce hair shedding, despite using finasteride and minoxidil for 9 months.

      community Treatment of Male Pattern Baldness with Botulinum Toxin

      in Treatment  9 upvotes 7 years ago
      The conversation discusses using Botox to treat male pattern baldness, suggesting it may promote hair growth by increasing scalp blood flow and oxygen, reducing dihydrotestosterone levels. The user wonders why this treatment is not widely discussed or if it has been discredited.

      community Intermittent fasting reduces hair growth?!? :(

      in Research/Science  36 upvotes 1 year ago
      Intermittent fasting may inhibit hair growth by triggering a stress response that affects hair-follicle stem cells. Some users believe genetics and DHT play a larger role in hair loss, and treatments like Minoxidil and Finasteride are mentioned as ineffective for some.

      community [Research/Science] What's the General Consensus On Pyrilutamide So Far?

      in Research/Science  8 upvotes 3 years ago
      Pyrilutamide is considered to work for hair loss but less effectively than expected, similar to RU58841, and may cause side effects like chest tightness and sexual issues. It's unclear if it's suitable for diffuse thinners, and one user cannot use minoxidil or finasteride due to side effects and personal circumstances.

      community Is a second shed normal on finasteride?

      in Finasteride/Dutasteride  2 upvotes 3 weeks ago
      Hair thickness can fluctuate while on finasteride, possibly due to product overuse or other factors like health or hormones. The user experienced a significant thinning in November 2025 but noticed improvement since then.

      community 21M cant stop hairloss at all +2 years on dut/fin

      in Finasteride/Dutasteride  8 upvotes 6 months ago
      A 21-year-old male has been experiencing persistent hair loss despite using treatments like dutasteride, finasteride, RU58841, minoxidil, and ketoconazole. Suggestions include checking for hormonal issues, nutritional deficiencies, or allergies, and consulting a doctor for professional advice.

      community Why Is No One Talking About Chromosome 20?

      in Chat  32 upvotes 7 months ago
      Some hair loss may be linked to chromosome 20, which isn't affected by DHT blockers like finasteride. Treatments like minoxidil, microneedling, and genetic testing are suggested, but their effectiveness for this type of hair loss is uncertain.

      community Track hairline of Pelage executives

      in Research/Science  36 upvotes 6 months ago
      Pelage executives' hairlines were discussed, with speculation about them using PP405 for hair regrowth. Concerns were raised about using untested drugs, with some suggesting executives might not risk using them without safety data.

      community Sugar and hairloss

      in Research/Science  8 upvotes 5 years ago
      Cutting sugar may not significantly impact hair loss, as DHT and androgen receptors are the main issues. Effective treatments include finasteride, dutasteride, RU58841, and minoxidil, often combined with microneedling.

      community Finasteride vs RU58841 vs Dutasteride for MPB, Diffuse Thinning, or Retrograde Alopecia

      in Minoxidil  6 upvotes 1 year ago
      The user is seeking advice on the best treatment for male pattern baldness, diffuse thinning, and retrograde alopecia, comparing the effectiveness of finasteride, RU58841, and dutasteride, and considering whether to add minoxidil or switch to dutasteride or combine treatments. They are currently on finasteride and are contemplating if adding RU58841 or switching to dutasteride is better, and also asking about the comparison between pyrilutamide and RU58841.

      community How the hell am I still losing hair

      in Finasteride/Dutasteride  8 upvotes 6 months ago
      The user has been experiencing sudden and aggressive hair shedding despite using oral dutasteride and topical minoxidil for six years, and recently added topical finasteride without improvement. Possible causes discussed include stress-related hair loss, dietary changes, or high DHT sensitivity, with suggestions to consult a doctor and consider adjusting treatments.

      community The expected timeline for PP405 - Next update at AAD Annual Meeting in March 2026 ?

      in Treatment  30 upvotes 3 months ago
      A new hair loss treatment, PP405, showed promising Phase 2a results with 31% of patients experiencing over 20% hair density increase without systemic absorption, avoiding hormonal side effects. The treatment is expected to be expensive, with Phase 3 trials starting mid-2026, and there is skepticism about the data's strength.