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      community Additional supplements / peptides to maximize finasteride benefit

      in Research/Science  3 upvotes 3 weeks ago
      The user is using finasteride, HGH, GHK-CU, BPC-157, KPV, biotin/collagen/keratin vitamins, ketoconazole shampoo, and low-dose naltrexone to address hair loss, avoiding minoxidil due to past shedding experiences. Adenosine is discussed as a potential alternative to minoxidil, though it is noted to be expensive and hard to find.

      community No side effects on pyrilutamide / KX-826 so far

      in Research/Science  207 upvotes 4 years ago
      User TopBack56 and friends tried pyrilutamide (KX-826) for hair loss without experiencing negative side effects. They observed fine vellus hairs but no thick hair growth yet, and plan to add GT20029 to their regime after safety trials.

      community What ever happened to pyrilutamide?

      in Technology  48 upvotes 3 years ago
      Pyrilutamide, a potentially effective hair loss treatment; other topical treatments like RU58841 and CB-03-01 that may have fewer side effects than Pyrilutamide; and the Phase 3 clinical trials of Pyrilutamide, which is likely to be approved by the FDA soon.

      community Update on PP405 Trails - Pelage

      in Research/Science  14 upvotes 4 months ago
      The conversation discusses interest in participating in PP405 trials for hair loss treatment, with users expressing uncertainty about eligibility due to location. Participants are eager for updates and willing to pay for shipping if trials are limited to America.

      community AHK-cu peptides experiences and sources to buy

      in Product  5 upvotes 1 year ago
      AHK-cu peptides are discussed for hair growth, with users comparing them to GHK-cu peptides and sharing sources to buy. AHK-cu is noted as more expensive, and users express interest in finding cheaper, reliable vendors.

      community Groundbreaking complete hair regrowth wonder drug found!!!

      in Satire  915 upvotes 11 months ago
      A satirical post humorously discusses a fictional hair regrowth drug called PP405, with users joking about its effectiveness and bizarre presentation. The conversation includes humorous reactions and references to the absurdity of the content.

      community Does anyone else have experience with Patented Growth Factors (PGF) Treatments / experiences with depression on Fin/Min/Dut?

      in Treatment  1 upvotes 1 year ago
      The user is exploring hair loss treatments, including Patented Growth Factors (PGF) and a serum with Copper Peptide, Ceramides, Amino Acids, and Caffeine, while expressing concerns about the cost and effectiveness of PGF. They are also considering starting finasteride due to doubts about PGF's long-term viability and are seeking experiences from others who have used these treatments alongside antidepressants.

      community TE turned into Scarring hairloss

      in Update  12 upvotes 2 years ago
      The user experienced hair loss due to a crash diet and later developed scarring hair loss. They are now on finasteride, oral minoxidil, LDN, Zyrtec, and Oztela to reduce scalp inflammation and promote hair regrowth.

      community The lowest cyproterone dose to stop mpb

      in Treatment  4 upvotes 2 years ago
      The conversation discusses using cyproterone acetate at 12.5 mg to manage hair loss, with concerns about its effects on testosterone and potential health issues. Other treatments mentioned include finasteride, dutasteride, minoxidil, and RU58841, with varying experiences and outcomes.

      community HT / Meds results are reverting, thinning, crazy shedding..

      in Progress Pictures  164 upvotes 1 year ago
      A user experienced significant hair shedding and thinning 10 months post-hair transplant despite using minoxidil and topical finasteride. They are considering switching to oral finasteride or dutasteride and are also dealing with scalp conditions like seborrheic dermatitis.

      community PP405 mechanism question - looking for discussion

      in Treatment  6 upvotes 2 months ago
      PP405 may promote short-term hair growth by pushing follicles into the growth phase, but concerns exist about long-term effects due to lack of rest phases. Users discuss various treatments like finasteride, minoxidil, spironolactone, alfatradiol, and investigational drugs like KX-826 and GT20029 for hair maintenance and regrowth.

      community High Estrogen and Test on Dut 5x a week

      in Finasteride/Dutasteride  6 upvotes 1 year ago
      A user experienced increased pimples and cysts after two years on dutasteride, possibly due to hormonal changes. Suggestions included seeing an endocrinologist, using supplements like boron and DIM, adjusting diet, and reducing body fat to manage side effects.

      community u/joaopassos4444 has zero education in endocrinology, human biology or science, it’s incredibly unlikely he good Will Hunting-ed a medical issue that stumped researchers for thousands of years, please stop buying random supplements based on layman speculation and temper your expectations

      in Research/Science  69 upvotes 5 years ago
      User questions credibility of a hair loss "cure" found by a non-expert and warns against wasting money on unproven supplements. Others discuss trying natural extracts and the importance of researching the enzyme 3ADH for potential hair growth benefits.

      community Had anyone used peptides for help with regrowth?

      in Treatment  7 upvotes 10 months ago
      Peptides like GHK-Cu are discussed for hair regrowth, with mixed results; some users report no regrowth, while others notice thicker hair. Topical application is common, and proper sourcing and mixing are emphasized.

      community What's going on with hmi115? The Phase 2 was concluded Nov2024 but no news

      in Chat  12 upvotes 6 months ago
      Hmi115, a prolactin receptor blocker, showed promise for hair growth, but results from Phase 2 trials have not been published. ABS-201, an AI-based analog, is expected to begin trials in December 2025, while commercialization of treatments like PP-405 is anticipated around 2027.

      community Adrogens and Covid-19

      in Treatment  7 upvotes 5 years ago
      The possible increased risk of severe Covid-19 cases in men due to higher androgen levels, and how taking medications such as finasteride, dutasteride, spironolactone, enzalutamide, or canabidiol might help mitigate the severity of the disease.

      community 1 year Fin/2 months GHK-CU update

      in Update  128 upvotes 3 weeks ago
      The user has been using oral finasteride for over a year and recently added GHK-CU for two months, seeing progress but seeking further improvement, especially on the hairline. They discuss sourcing GHK-CU, its effects, and the importance of third-party testing, while considering additional treatments like dutasteride and hair transplants for better results.

      community Switch from RU58841 to Pyrilutamide, after 2 years?

      in Treatment  6 upvotes 3 years ago
      A user switched from RU58841 to Pyrilutamide for hair loss treatment after experiencing side effects and continued hair shedding with RU. They are now losing hair faster with Pyrilutamide and questioning if they should revert to RU58841.

      community Found a slide summary for PP405

      in Research/Science  33 upvotes 2 months ago
      PP405 shows promise in stimulating new terminal hair growth by activating dormant follicles, with no systemic adverse effects observed in a short-term trial. However, long-term efficacy remains unproven, and further trials are needed to confirm its potential as a hair loss treatment.

      community BPC-157 and Angiogenesis. Bro-Science-Execution-Plan

      in Research/Science  13 upvotes 11 months ago
      BPC-157 may promote hair growth by increasing angiogenesis, similar to how Minoxidil works, though no direct research confirms this yet. Users report combining BPC-157 with Minoxidil and finasteride for better results, but concerns about long-term safety exist.

      community The homeless crackhead protocol

      in Satire  4488 upvotes 9 months ago
      The conversation humorously suggests that drug use might be more effective for hair retention than traditional treatments like minoxidil or finasteride. It attributes full heads of hair in homeless individuals to lifestyle factors like reduced stress or hormonal changes.

      community Reflex Hyperandrogenicty: How I recovered from it

      in Treatment 2 years ago
      The user experienced severe hair shedding from RU58841 and recovered by stopping its use and starting treatments including Minoxidil, Rosemary Verbenone, Stemoxydine, Aminexil, copper peptide serum, and specific shampoos. They also consistently used oral Finasteride and plan to try Minoxidil 10%.