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      community Questions about DUPA and figuring out what my hairloss is (NEED INPUT BADLY)

      in Finasteride/Dutasteride  5 upvotes 11 months ago
      The conversation discusses severe hair shedding and thinning, with the original poster using finasteride, oral minoxidil, and other supplements without improvement. The discussion highlights the possibility of telogen effluvium and the importance of addressing potential underlying health issues, such as stress and gut health, rather than assuming diffuse unpatterned alopecia (DUPA).

      community Bile Acid-Mediated DHT Dysregulation Hypothesis

      in Research/Science  13 upvotes 1 year ago
      Elevated bile acids can inhibit the enzyme AKR1C2, leading to increased DHT levels, which may accelerate hair loss in those predisposed to androgenetic alopecia. Treatments mentioned include topical minoxidil and finasteride.

      community Petition: Make PP405 available tomorrow instead of 2030

      in Satire  335 upvotes 9 months ago
      PP405, a promising hair loss treatment, is expected to be available by 2027, with faster trials due to its topical nature. Users are eager for its release, comparing it to existing treatments like minoxidil and finasteride, but remain cautious about its long-term effectiveness.

      community 1 year 5-ar. Blood test results

      in Finasteride/Dutasteride  3 upvotes 8 months ago
      The user experienced sexual side effects after starting finasteride and later switched to dutasteride, noticing hormonal changes. They are considering using P5P and possibly aromatase inhibitors to manage high prolactin and estradiol levels.

      community Increased b12 and hair loss correlation

      in Female  2 upvotes 1 year ago
      A user noticed increased hair loss after taking B12 supplements for two months, with B12 levels rising to 1500. They are seeking help as other tests show normal levels of minerals and vitamins.
      Help me interpret my bloods

      community Help me interpret my bloods

      in General  65 upvotes 10 months ago
      The user is concerned about high prolactin levels and low testosterone levels after stopping finasteride for three weeks. They are considering resuming finasteride but are worried it might further increase prolactin levels.

      community Help interpreting pre-fin bloodwork

      in Finasteride/Dutasteride  12 upvotes 4 years ago
      A 20-year-old male is unsure how to interpret his bloodwork results and whether he should take finasteride for hair loss. His bloodwork shows borderline high levels of albumin and testosterone, and high progesterone, but normal levels of other hormones.

      community Dermastamp vs Dermaroller vs Dermapen

      in Microneedling  5 upvotes 7 months ago
      Dermastamp is preferred for hair growth and skin health due to fewer scars, with recommended needle sizes of 0.5-1.5mm. Dermapen is also favored over dermarollers, which are considered dangerous.

      community GT20029 Anageninc Market Availability

      in Research/Science  168 upvotes 3 years ago
      The conversation discusses the potential market release of a hair loss treatment called GT20029 by Anageninc, with users expressing interest and discussing the importance of safety and effectiveness. Some users plan to contact Anageninc to show demand for the product.

      community 5 month min fin + dermaroll xd

      in Progress Pictures  160 upvotes 2 years ago
      The post is about a user's progress with using minoxidil and finasteride for hair loss. One user suggests that dermarolling may also be contributing to the positive results.

      community Ultimate Non-5AR (fin/dut) stack?

      in Treatment  1 upvotes 11 months ago
      The conversation discusses alternatives to 5AR inhibitors for hair loss treatment, suggesting options like minoxidil, KX-826, pyrilutimide, microneedling, and topical bicalutamide. Concerns about side effects and the effectiveness of these treatments are also highlighted.

      community Has anyone tried PRP and Exosomes?

      in Chat  2 upvotes 2 years ago
      The user asked for opinions on a hair loss treatment involving PRP and Exosomes. They recently tried this treatment.

      community MCL1 does anyone knows anthying about it

      in Research/Science  9 upvotes 11 months ago
      MCL-1 protein may help maintain hair follicles in the growth phase and prevent miniaturization. There is interest in experimental treatments like exosomes, peptides, or stem cell serums to upregulate MCL-1 for hair loss, especially for those not using minoxidil or finasteride.

      community Is this the nuclear stack? Wanna go from NW3 to NW1 at the age of 23

      in Treatment  20 upvotes 2 months ago
      A user is considering an extensive hair loss treatment regimen including oral dutasteride, oral minoxidil, topical finasteride, tretinoin, microneedling, keto shampoo, laser comb, and PRP injections. Suggestions include simplifying the routine, possibly increasing minoxidil dosage, and considering alternatives like RU58841, while cautioning against using estrogen due to potential side effects.

      community FYI you can't donate blood when on fin/dut

      in Finasteride/Dutasteride  269 upvotes 7 months ago
      People on finasteride or dutasteride cannot donate blood due to the risk of birth defects if the blood is given to a pregnant woman. It's advised to stop finasteride for a month and dutasteride for six months before donating.

      community Starting Pyrilutamide BID. First dose was yesterday. Diffuse thinning. I will put my full regimen below.

      in Research/Science  89 upvotes 3 years ago
      A user's regimen to help with their diffuse thinning, which includes taking Pyrilutamide BID, 1mg finasteride daily, 2.5mg oral minoxidil daily, topical minoxidil since August 2021, LLLT every two days, topical fin, progesterone, melatonin, minoxidil (started one week ago), pumpkin seed oil and not dermarolling; other commenters suggested Nizoral for dandruff control and caution when using pre-mixed products with Pyrilutamide.

      community Sooo whens the next big thing gonna come?

      in Chat  15 upvotes 6 days ago
      New hair loss treatments like VDPHL01, PP405, Gt20029, and Breezula are anticipated, with VDPHL01 possibly releasing in 2027/28. Current treatments include finasteride, dutasteride, and minoxidil, but new options are eagerly awaited.

      community Will pp405 have to be inserted rectally for full benefits?

      in Transgender  32 upvotes 4 months ago
      Pp405 is discussed as a potential hair loss treatment, with humorous suggestions about rectal administration for increased effectiveness. Users joke about unconventional methods and express willingness to try anything for hair regrowth.

      community Bloodwork post finasteride gyno sides

      in Finasteride/Dutasteride  8 upvotes 4 years ago
      The user stopped using finasteride after two weeks due to gynecomastia symptoms and shared blood work results questioning if they indicate a cause for the side effects. The user is considering restarting finasteride and seeking advice on their blood work levels in relation to gynecomastia.

      community Better Than Minoxidil? Topical Sodium Valproate

      in Research/Science  51 upvotes 1 year ago
      Topical sodium valproate may promote hair growth by inhibiting GSK3β, allowing beta-catenin to proliferate, but it has potential side effects and requires more research. The conversation also mentions skepticism about a product called Vdphlo1, which includes sodium valproate and other ingredients.