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      community Can we get a reality check on PP405?

      in Research/Science  81 upvotes 7 months ago
      PP405 is a promising hair loss treatment that may outperform minoxidil and finasteride by reviving dormant follicles and promoting significant regrowth. Results from ongoing trials are awaited, with a potential market release between 2028-2030.

      community OFFICIAL Multi-Center Verteporfin Trial Recruitment

      in Research/Science  251 upvotes 1 year ago
      Recruitment for a verteporfin trial and a separate hair cloning trial using verteporfin and other methods is underway, with locations in Jordan, NYC, Beverly Hills, and Memphis. Dr. Bloxham is conducting the hair cloning trial, and interested participants are encouraged to contact him directly.

      community When should we get the next news about PP405

      in Chat  25 upvotes 7 months ago
      Results for PP405 are expected next year, with concerns about its pricing and potential black market availability. Some users believe it may be slightly more effective than finasteride and dutasteride, and combining it with treatments like minoxidil and microneedling could be beneficial.

      community RU58841 KB Solution vs PG + Ethanol

      in Research/Science  6 upvotes 2 years ago
      The conversation discusses the differences between KB solution and PG + Ethanol solution for RU58841 in treating hair loss. It compares the effectiveness and properties of these two solutions.

      community Pelage are going to do two phase 3 trials for PP405. How long will it take to complete two phase 3 trials?

      in Chat  45 upvotes 5 months ago
      Pelage plans to conduct two Phase 3 trials for PP405, a new hair loss treatment, which may take about a year to complete. Users discuss various hair loss treatments, including pyrilutamide, minoxidil, finasteride, and clascoterone, with some expressing impatience over the lengthy trial process compared to faster drug approvals like the COVID vaccine.

      community BPC-157 and Angiogenesis. Bro-Science-Execution-Plan

      in Research/Science  13 upvotes 11 months ago
      BPC-157 may promote hair growth by increasing angiogenesis, similar to how Minoxidil works, though no direct research confirms this yet. Users report combining BPC-157 with Minoxidil and finasteride for better results, but concerns about long-term safety exist.

      community Possible natural pp405 solution

      in Research/Science  45 upvotes 9 months ago
      Rotenone, a natural plant extract, may promote hair growth by increasing LDH activity and blocking MPC in the scalp, but it carries risks due to its toxicity. The suggested formulation includes Barbasco extract, DMSO, propylene glycol or PEG-400, ethanol, and a carrier oil.

      community Where do you buy your Verteporfin?

      in Product  2 upvotes 1 year ago
      A user is seeking advice on treating a chin scar with Verteporfin, noting that higher doses were more effective. Another user responds that they do not use it, without providing further explanation.

      community Dr. Bloxham's Verteporfin Trial

      in Research/Science  30 upvotes 2 years ago
      Dr. Bloxham's trial is testing verteporfin on hair transplant patients to see if it can improve hair regrowth in treated areas. People are discussing the potential for follicle regeneration, expected results timeline, and concerns about side effects like cancer.

      community Thoughts on the future of pp405?

      in Research/Science  43 upvotes 7 months ago
      PP405 is considered a promising hair loss treatment, potentially replacing minoxidil but not finasteride. Users are hopeful for future treatments like GT20029 and VDPHL01, while remaining cautious about effectiveness and side effects.

      community Vertoporfin research update by Dr Bloxham

      in Research/Science  71 upvotes 2 years ago
      The conversation discusses the potential of verteporfin in treating hair loss, with some users reporting positive results and speculating that it could lead to a cure for baldness. Others are skeptical, and there's a debate on the effectiveness of verteporfin for regrowing hair and reducing transplant scars.

      community Let’s get PP405 trending on Twitter!

      in Chat  69 upvotes 11 months ago
      People are excited about a new hair loss treatment, PP405, and some suggest using Twitter to increase its visibility. Current treatments mentioned include finasteride, minoxidil, and dutasteride, but skepticism remains about the effectiveness of new treatments.

      community Hot Take: Betting on PP405 can backfire

      in Research/Science  81 upvotes 11 months ago
      PP405 is seen as promising but uncertain, with users advised to continue using existing treatments like minoxidil and finasteride. Concerns include its cost, availability, and interaction with hair transplants, while some hope it could complement current treatments.

      community Pelage PP405 Phase 2a completed.

      in Research/Science  61 upvotes 4 months ago
      Minoxidil, finasteride, and RU58841 are discussed as treatments for hair loss, with excitement around a new drug, PP405, and a reformulated oral minoxidil in trials. Concerns about cost, side effects, and long-term use are also mentioned.

      community Figuring out my own experimental protocol

      in Treatment  11 upvotes 3 years ago
      User tries dermapen for hair loss and plans to use non-mainstream topicals like c60, ghk-cu, and ptd-dbm with valproic acid. They also use a head massager and modified LLLT belt for additional treatment.

      community Helicobacter's concocted serum v1

       6 upvotes 7 years ago
      A custom-made serum based on double-blind studies for AGA, which includes natural ingredients such as rosemary oil, procyanidin B-2, saw palmetto extract, curcuma aeruginosa, pumpkin seed oil and castor oil. The user has updated their recipe to include apple poly procyanidin B-2 4% concentration and other ingredients before topping it off with Pura d'or serum.

      community PP405 - hair stem cell stimulation

      in Research/Science  53 upvotes 2 years ago
      PP405, a topical LDH inhibitor, has shown to stimulate hair follicle stem cell proliferation in humans with moderate hair loss. They are advancing to more detailed trials this year.

      community 35M, 4000 Grafts, Dr Patty, HairTran Clinic, Bangkok

      in Progress Pictures  65 upvotes 5 months ago
      A 35-year-old man underwent a hair transplant with Dr. Patty at HairTran Clinic in Bangkok, receiving 4,037 grafts primarily for his crown area. The procedure cost 188,700 THB, with an additional 12,000 THB for optional PRP treatment, and he plans to update with progress pictures in a year.

      community I wish pp405 work and i have full head of hair in 2028-2030

      in Chat  106 upvotes 7 months ago
      People are hopeful about future hair loss treatments like PP405, GT20029, and VDPHL01, while some are currently using finasteride and minoxidil. There is skepticism about the effectiveness of new treatments, and some advise against hair transplants until more promising drugs are available.