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      community Boston Transplant Update. Hairline & Crown procedures!

      in Progress Pictures  4 upvotes 1 month ago
      The user underwent a hair transplant in Boston, initially dissatisfied with the results, but later achieved significant improvement in hair density and natural appearance after consulting a different surgeon. They used finasteride, minoxidil, and low-level laser therapy as part of their treatment.

      community Brainstorming: upping your dermarolling game

      in Research/Science  5 upvotes 2 years ago
      The conversation is about enhancing dermarolling for hair loss by using topical peptides like tb-500 or GHK-Cu to aid in healing and hair growth, and whether anyone has experienced significant results from this method.

      community Track hairline of Pelage executives

      in Research/Science  39 upvotes 5 months ago
      Pelage executives' hairlines were discussed, with speculation about them using PP405 for hair regrowth. Concerns were raised about using untested drugs, with some suggesting executives might not risk using them without safety data.

      community OFFICIAL Multi-Center Verteporfin Trial Recruitment

      in Research/Science  251 upvotes 10 months ago
      Recruitment for a verteporfin trial and a separate hair cloning trial using verteporfin and other methods is underway, with locations in Jordan, NYC, Beverly Hills, and Memphis. Dr. Bloxham is conducting the hair cloning trial, and interested participants are encouraged to contact him directly.

      community Dermarolling for Diffused Thinning.

      in Treatment  4 upvotes 7 years ago
      The user experienced noticeable hair growth after starting dermarolling with a 1mm device, using minoxidil, and nizoral shampoo. They plan to reduce dermarolling frequency to three times a week and are considering additional treatments like finasteride or a hair transplant for increased hair density.

      community PP405 is NOT gray market jxl069

      in Technology  26 upvotes 2 months ago
      PP405 is a safer alternative to JXL069 for hair loss treatment because it penetrates the skin effectively and degrades in the blood, avoiding systemic toxicity. JXL069, when forced into the body, can cause dangerous side effects like lactic acidosis due to its inability to degrade safely.

      community Tressless Pyrilutamide data analytics – Frustrated with lack of data, so I did something about it!

      in Treatment 3 years ago
      This user has conducted data scraping of 365 Reddit posts on the hairloss drug Pyrilutamide over the last year to analyse efficacy and side effects. The findings, which are available in a 19 page report with graphs, suggest that 22% of Pyrilutamide users experience positive results while 63% experience symptoms. A larger analytics project is proposed for other drugs with enough demand.

      community Trialing the probiotics BB536, PTA 6475 so you don’t have to

      in Research/Science  72 upvotes 9 months ago
      Probiotics like L. reuteri ATCC PTA 6475 and B. longum BB536 may improve hair growth and density by reducing inflammation and reversing DHT damage. The user is trialing these probiotics personally, ordering them from the U.S. to Canada, and plans to continue if no adverse effects occur.

      community AA and Hirsutism but T levels are normal

      in Female  7 upvotes 5 years ago
      27-year-old female experiences aggressive hair thinning and hirsutism despite normal testosterone levels. Spironolactone and 2% minoxidil were ineffective; high DHEA sulfate levels may be the cause.

      community Pelage are starting phase 3 for PP405 towards the end of 2026

      in Chat  180 upvotes 1 month ago
      PP405 is moving to late-stage trials, showing potential for hair regrowth, with 31% of male patients experiencing a 20% increase in hair density. Veradermics is developing an oral minoxidil version, and there is interest in combining treatments for better results.

      community How strong is topical spiro? Close to God tier stack.

      in Product  8 upvotes 2 years ago
      Topical spiro's effectiveness on androgens is discussed. User tried oral DUT, oral Min, keto/nizoral, and RU but experienced worsening hair loss and chest pains. Suggestion given to increase dutasteride and oral minoxidil dosage before considering spironolactone.

      community Cmon Pyrilutamide and CosmeRNA 😭

      in Chat  34 upvotes 2 years ago
      Users discuss waiting for new hair loss treatments and share struggles with side effects from current options like Minoxidil and Finasteride. They express hope for Pyrilutamide and CosmeRNA to provide better solutions.

      community 3 surgery total 7600 Grafts surgery journey

      in Progress Pictures  727 upvotes 2 months ago
      A person had three hair transplant surgeries using 7,600 grafts from scalp, beard, and chest, along with finasteride and minoxidil. Reactions are mixed, with suggestions for alternatives like hair systems or scalp micropigmentation.

      community MSM [Methylsulfonylmethane] ??

      in Treatment  5 upvotes 2 years ago
      Methylsulfonylmethane (MSM) is not a treatment for male pattern baldness but can accelerate hair growth and thicken miniaturized hairs, with the side effect of increased hair growth all over the body. The user asks others to share their experiences with MSM.

      community Bimatoprost (Lumigan) for MPB?

      in Treatment  4 upvotes 3 years ago
      The conversation discusses using Bimatoprost for eyebrow regrowth and its potential use on the hairline, with concerns about cost and side effects. Alternatives like topical Minoxidil are mentioned, but the user is worried about aging and acne.

      community What should I do, should I be concerned?

      in Finasteride/Dutasteride  2 upvotes 2 years ago
      The user began experiencing hair loss a few years ago at age 22 and is a diffuse thinner with a Norwood scale rating of 2. They have a naturally athletic build and gain muscle easily, with a hairy chest and stomach.

      community Hair Transplant @ Hairtran Clinic (3545 Grafts) (~$3600USD)

      in Transplants  51 upvotes 2 years ago
      A user shared their positive hair transplant experience at Hairtran Clinic in Thailand, costing about $3600 for 3545 grafts, and mentioned being on oral finasteride and minoxidil for six months. Other users confirmed good results with the same clinic, noting it takes around six months to see significant improvement.

      community Bryan Johnson’s Hairloss Regimine

      in Research/Science  26 upvotes 2 years ago
      The post is about Bryan Johnson's hair loss regimen, which includes dutasteride mesotherapy, minoxidil, microneedling, and red laser therapy. The conversation includes discussions about the effectiveness of topical dutasteride and speculation about whether Bryan Johnson has had a hair transplant.
      PP405 Identity Research

      community PP405 Identity Research

      in Research  292 upvotes 7 months ago
      PP405 is a potential hair loss treatment that inhibits mitochondrial pyruvate carriers, increasing lactate dehydrogenase activity and stimulating hair follicle stem cells. In a phase 1 trial, 31% of participants showed over 20% hair density increase with PP405 treatment.

      community Further prolactin research....

      in Research/Science  6 upvotes 2 years ago
      HMI 115 did not work as expected for hair regrowth in humans, unlike in macaque monkeys. There is anticipation for further research on prolactin's role in hair loss, with expectations that pharmaceutical companies will likely solve this before universities.
      TresslessGPT is now available for free

      community TresslessGPT is now available for free

      in General  386 upvotes 1 year ago
      Tressless GPT is now free and accessible for hair loss advice. Treatments discussed include Minoxidil, finasteride, RU58841, dutasteride mesotherapy, topical melatonin, microneedling, and rapamycin.