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      community 2 years of 5% topical minoxidil + 1 year of 1mg finasteride.

      in Progress Pictures  236 upvotes 2 months ago
      The user shared progress pictures after using 5% topical minoxidil for two years and 1mg finasteride for one year, but many commenters believe the hair looks the same, attributing changes to different haircuts rather than actual regrowth. The user reported no side effects from finasteride, and opinions varied on whether any significant hairline improvement occurred.

      community Hair Loss Causes Depression. Not Finasteride.

      in Research/Science  188 upvotes 4 months ago
      Finasteride and Dutasteride do not cause depression or mood disorders; hair loss itself may be a more significant factor. Some users experience side effects from Finasteride, but it is generally well-tolerated.

      community Occipitalis Muscle Tension Theory

      in Treatment  10 upvotes 4 months ago
      Scalp tension from the occipitalis muscle is theorized to contribute to hair loss, but most believe DHT and genetics are the main causes. Treatments like finasteride and minoxidil are considered more effective than addressing scalp tension.

      community Regrowth with only Nizoral and Lifestyle Changes; focusing on scalp health & nervous system

      in Is this regrowth?  87 upvotes 4 months ago
      The user reported subtle hair regrowth by focusing on scalp health and lifestyle changes, using Nizoral shampoo and methods to reduce inflammation and cortisol, without using finasteride, minoxidil, or other common treatments. Opinions in the conversation varied, with some skeptical of the results and others acknowledging the potential benefits of addressing scalp health and inflammation.

      community 2.5 years 1mg finasteride daily

      in Progress Pictures  4864 upvotes 5 months ago
      Significant hair regrowth was achieved after 2.5 years of taking 1 mg finasteride daily, without using minoxidil or microneedling. Minor side effects included a slightly thinner beard and longer time to finish during sex.

      community It is what it is with some people

      in Satire  162 upvotes 5 months ago
      Hair loss treatments like finasteride and dutasteride are discussed, with concerns about side effects such as depression and brain fog. Some users argue about the necessity and impact of DHT on libido and other bodily functions.

      community I’m considering stopping finasteride

      in Finasteride/Dutasteride  157 upvotes 5 months ago
      The user is considering stopping finasteride due to depression, anxiety, and difficulty building muscle, despite its effectiveness in stopping hair loss. Suggestions include reducing the dose, switching to topical solutions, or consulting a doctor for alternatives like dutasteride or RU58841.

      community The expected timeline for PP405 - Next update at AAD Annual Meeting in March 2026 ?

      in Treatment  30 upvotes 6 months ago
      A new hair loss treatment, PP405, showed promising Phase 2a results with 31% of patients experiencing over 20% hair density increase without systemic absorption, avoiding hormonal side effects. The treatment is expected to be expensive, with Phase 3 trials starting mid-2026, and there is skepticism about the data's strength.

      community Thoughts on the future of pp405?

      in Research/Science  43 upvotes 7 months ago
      PP405 is considered a promising hair loss treatment, potentially replacing minoxidil but not finasteride. Users are hopeful for future treatments like GT20029 and VDPHL01, while remaining cautious about effectiveness and side effects.

      community PP405 Update and My Take on Pelage

      in Research/Science  86 upvotes 8 months ago
      Pelage Pharmaceuticals raised $120M for their hair loss treatment, PP405, showing strong investor confidence despite limited data. There is skepticism about its efficacy and long-term effects compared to treatments like GT20029.

      community Creatine is the opposite of minoxidil !

      in Research/Science  315 upvotes 8 months ago
      Creatine may counteract minoxidil's hair growth effects by closing potassium ATP channels, potentially leading to hair loss in predisposed individuals. Despite anecdotal reports, there is no conclusive evidence linking creatine to hair loss.

      community I cannot even tolerate Nutrafol

      in Product  6 upvotes 8 months ago
      The user experienced side effects from finasteride and Nutrafol, opting for non-hormonal treatments like minoxidil, exercise, and a healthy lifestyle. Others discussed using Dutasteride, Biotin, and minoxidil with varying success and side effects.

      community One year on finasteride has reversed some aging

      in Chat  198 upvotes 8 months ago
      Finasteride and minoxidil use resulted in a more youthful appearance and improved skin. There is debate about their effects on collagen and skin aging, with no solid evidence supporting significant changes due to finasteride.

      community Can we stop fear mongering with finasteride

      in Finasteride/Dutasteride  285 upvotes 8 months ago
      Finasteride is effective for hair loss but can cause sexual dysfunction and mental health issues in some users, leading to a polarized debate on its risks. Some switch to alternatives like Dutasteride or topical treatments to avoid side effects.

      community Topical dutasteride is superior to oral finasteride

      in Research/Science  96 upvotes 8 months ago
      Topical dutasteride is more effective than oral finasteride for male pattern hair loss, with fewer side effects. Some prefer oral treatments for convenience, while others use topical solutions like minoxidil and dutasteride, sometimes with microneedling, for better results.

      community Dht kills hair, but no one says why?

      in Finasteride/Dutasteride  40 upvotes 9 months ago
      DHT affects hair follicles, contributing to hair loss, but the exact mechanism is unclear. Treatments like finasteride and minoxidil are used to manage hair loss, though they may have side effects and varying effectiveness.

      community Openminded Creatine Discussion

      in Product  10 upvotes 9 months ago
      Creatine may cause hair shedding in some individuals, particularly those with genetic sensitivity to hair loss, but this is not universally experienced. Finasteride users report mixed results, with some experiencing resumed shedding when taking creatine.

      community PP405 is out for sale on everychem.

      in Product  98 upvotes 10 months ago
      PP405 is suspected to be a scam, with users doubting its legitimacy and effectiveness. Many recommend using proven treatments like finasteride and minoxidil.

      community Why do we get bald from evolutionary perspective

      in Chat  213 upvotes 11 months ago
      Baldness is not an evolutionary disadvantage because it occurs after reproductive age. Treatments like Minoxidil and Finasteride are used for androgenetic alopecia but don't address the root cause.

      community Hairloss has destroyed my Life completely

      in Chat  339 upvotes 11 months ago
      A young person is distressed about rapid hair loss despite using finasteride and recently starting oral minoxidil. Many suggest continuing treatment, considering dutasteride, and seeking therapy for mental health support.

      community Getting PP405. Now…. or as soon as possible

      in Research/Science  145 upvotes 1 year ago
      People are discussing obtaining and testing PP405 for hair loss treatment, with concerns about its purity and effectiveness. Some are considering delaying hair transplants, while others suggest using existing treatments like finasteride and minoxidil.