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      community P-1075: a BETTER version of Minoxidil

      in Research/Science 7 months ago
      P-1075 is a more potent hair growth agent than Minoxidil, but it poses significant heart risks, making it unsafe for use. Despite promising results in macaques, concerns about its cardiotoxicity in rats have halted its development.

      community 0.25 alfatradiol or 0.5 Pyrulitamide ?

      in Product  4 upvotes 7 months ago
      The conversation is about choosing an anti-androgen for hair loss treatment, with options being alfatradiol and pyrilutamide. Alfatradiol is considered a better choice due to its established use, while pyrilutamide is more experimental.

      community GHK-Cu peptide injections - what is your experience?

      in Research/Science  12 upvotes 2 months ago
      GHK-Cu peptide injections are discussed for hair growth, but users report mixed results and suggest focusing on DHT management first. Some users combine GHK-Cu with treatments like Minoxidil and Dutasteride, but emphasize its benefits for skin rather than hair.

      community Homemade pyri solution- problems

      in Treatment  1 upvotes 2 years ago
      A user mixed a pyrilutamide solution and noticed undissolved powder at the bottom, questioning if this is normal and how long to wait before applying it. They wished others good luck with their treatments.

      community AGA responded to steroid shots? Biopsy wrong? Please help!

      in Female  2 upvotes 1 year ago
      A woman with AGA is using spironolactone, dutasteride, finasteride, oral minoxidil, bicalutamide, and anti-androgenic birth control but still experiences worsening hair loss. Steroid shots temporarily stop her hair shedding, leading her to question her biopsy results.

      community What do you think about pyrilutamide?

      in Product  5 upvotes 1 year ago
      Pyrilutamide is being discussed as a potential hair loss treatment, but opinions are mixed, with some users skeptical about its effectiveness and the company's credibility. Some users report combining pyrilutamide with other treatments like dutasteride and microneedling, noting improvements, while others remain doubtful.

      community My experience and a discourse on “DUPA”

      in Chat  46 upvotes 3 years ago
      How diffuse unpatterned alopecia (DUPA) is not an invitation to self-diagnose oneself with aggressive AGA and that seeking a specialized dermatologist may help people experiencing hair loss. Treatment options discussed include topical clobetasol propionate, oral minoxidil, and discontinuing finasteride.

      community GT20029 Phase 2 results are out

      in Treatment  60 upvotes 5 months ago
      GT20029 shows promising results for hair loss treatment, with potential approval in China by 2026 or 2027, but U.S. approval may take longer. It could serve as an alternative to finasteride, with a potentially better side effect profile.

      community RU58841 in Pumpkin Seed Oil (PSO)

      in Treatment  4 upvotes 1 year ago
      A user is seeing good results with RU58841 for hair loss, noting reduced shedding and thicker hair. They plan to use pumpkin seed oil as a solvent to avoid water content, which they believe reduces the effectiveness of anti-androgens.

      community Update on PP405 Trails - Pelage

      in Research/Science  14 upvotes 3 months ago
      The conversation discusses interest in participating in PP405 trials for hair loss treatment, with users expressing uncertainty about eligibility due to location. Participants are eager for updates and willing to pay for shipping if trials are limited to America.

      community cosmeRNA finally now it's pyrilutamide turn

      in Chat  51 upvotes 3 years ago
      Hair loss treatments discussed include cosmeRNA, minoxidil, finasteride, RU58841, and pyrilutamide. Users debate effectiveness, side effects, and upcoming treatments, with some expressing skepticism and others optimism.

      community PP405 (Everychem 3HP) users - assemble and share your updates!!

      in Chat  47 upvotes 3 weeks ago
      Users discussed experiences with Everychem's solution similar to PP405 for hair loss, noting some positive results like increased hair thickness and new growth. There was skepticism about the product's legitimacy and safety, with some users reporting early signs of effectiveness and others expressing concerns about the lack of evidence and safety profiles.

      community Doubtful of RU58441's negative effects

      in Research/Science  2 upvotes 9 months ago
      RU58841's potential side effects, particularly heart palpitations, are debated, with some attributing them to contamination with minoxidil. Users report mixed experiences, with some seeing no side effects and others cautioning about the lack of reliable data on RU58841's safety.
      Eliminate/Confirm AGA based on blood report

      community Eliminate/Confirm AGA based on blood report

      in General  126 upvotes 10 months ago
      A 19-year-old male with no family history of androgenetic alopecia (AGA) is experiencing hair loss and considering using a topical minoxidil and finasteride mixture. Despite low vitamin D levels and normal DHT serum levels, he seeks confirmation of AGA before starting treatment.

      community Copper Peptides—Discussion

       4 upvotes 7 years ago
      Copper peptides, specifically GHK-Cu, are discussed as a potential addition to hair loss treatments, possibly working synergistically with Minoxidil to convert vellus hair into terminal hair. The effectiveness and credibility of copper peptides are questioned due to the lack of widespread discussion and potential conflict of interest from the product's creator.

      community Switch from RU58841 to Pyrilutamide, after 2 years?

      in Treatment  6 upvotes 3 years ago
      A user switched from RU58841 to Pyrilutamide for hair loss treatment after experiencing side effects and continued hair shedding with RU. They are now losing hair faster with Pyrilutamide and questioning if they should revert to RU58841.

      community Beating gyno symptoms on fin: my recent success

      in Update  18 upvotes 4 years ago
      A user successfully managed finasteride-induced gyno symptoms by making lifestyle changes, including fasting, avoiding soy, and increasing cardio. They resumed finasteride with a lower dose combined with minoxidil and P7 vitamins without recurrence of symptoms.