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300-330 / 1000+ resultscommunity Pyrilutamide phase III clinical trial results released
Pyrilutamide did not show effectiveness in regrowing hair compared to a placebo, but it may still help maintain existing hair by preventing DHT from causing follicle miniaturization. Some users believe it could be beneficial when used with other treatments like minoxidil, finasteride, and dutasteride.
community I wrote a poem about pp405 (potential treatment)
A poem humorously suggests hope for a new hair loss treatment, PP405, while users debate the effectiveness and side effects of current treatments like Finasteride. Concerns are raised about Finasteride's side effects, especially for young users, and skepticism about new treatments is expressed.
community Do People even realize that we got a new Treatment Option and Kintor Officially released Pyrilutamide?
A new hair loss treatment, Pyrilutamide, has been released and is claimed to be a strong anti-androgen, potentially effective when used with finasteride. However, there are mixed opinions on its effectiveness and safety, with some users skeptical and others purchasing it.
community Take your meds and hope, it may pay off
community Do these two supplements inhibit 5alpha-reductase?
Pumpkin Seed Oil and Perilla Oil (with alpha-lipoic acid, linoleic acid, and oleic acid) are discussed as potential 5alpha-reductase inhibitors. The conversation focuses on their effectiveness for hair loss treatment.
community Saw an opinion on PP405 and sharing
PP405 is discussed as a potential adjunct therapy for hair loss, with skepticism about its effectiveness and trial results. Users mention combining it with finasteride and minoxidil for better results, while others debate the root causes of hair loss and the limitations of current treatments.
community Supplements regime/suggestions
community Pyrilutamide release in Europe?
User asks about Pyrilutamide release in Europe, specifically Germany, and considers importing it from China. No specific treatments mentioned.
community Breezula Phase 3 Results enough for maintenance?
Breezula shows promise in stabilizing hair loss and potentially promoting regrowth at the one-year mark, offering hope for those who can't tolerate 5AR inhibitors. Its local targeting of androgen receptors could be a significant advancement if it avoids systemic side effects.
community Hot Take: Betting on PP405 can backfire
PP405 is seen as promising but uncertain, with users advised to continue using existing treatments like minoxidil and finasteride. Concerns include its cost, availability, and interaction with hair transplants, while some hope it could complement current treatments.
community Which telemedicine should I use to get a prescription written for as cheap as possible?
A 17-year-old is seeking affordable prescriptions for oral finasteride and minoxidil, considering lying about their age to use costplusdrugs. They are exploring telemedicine options, including Dr.B, to obtain the prescriptions.
community Australian options for topical Fin and Min?
An individual is seeking options for topical finasteride and minoxidil in Australia, considering products from Medicii Labs and exploring other suppliers. They plan to use a derma roller and caffeine + yerba mate hair wash alongside these treatments.
community Pyrilutamide (has anyone seen improvements)
Pyrilutamide and its effectiveness for treating hair loss, with advice from other users cautioning to wait at least 6 months before expecting any results. Treatments discussed include finasteride and minoxidil.
community Today was Last update on pp405
A new hair loss treatment, PP405, is moving from phase 2A to 2B in clinical trials, sparking discussions about its potential to regrow dormant hairs and its impact on existing treatments like Minoxidil and finasteride. Some users express skepticism, while others are hopeful about its future effectiveness.
community Any treatment not nuking systemic DHT levels?
Hair loss treatments that avoid significantly lowering systemic DHT levels, focusing on topical options like dutasteride mesotherapy, minoxidil, and ketoconazole. The user is exploring alternatives like KX-826 and RU58841 due to concerns about hormone levels.
community pyrilutamide – did anybody had any success on it?
Potential success with the hair loss treatment Pyrilutamide, and possible group buying opportunities for it along with other treatments such as Finasteride and Minoxidil.
community No Improvement on Finasteride.
Attempting to treat hair loss with Finasteride, and other treatments such as Minoxidil, RU58841, and DUT were suggested.
community Are these new hair loss treatments ever gonna release?
Hair loss treatments like Breezula and PP405 are delayed, with approvals taking years, while existing treatments like minoxidil and finasteride remain popular. New treatments like Clascoterone and Veradermics are in trials, but high costs and lengthy approval processes slow their release.
community Topical min/fin for 8 months. Still seeing continuous miniaturisation
After 8 months of using topical finasteride, hair miniaturization continues, raising concerns about its effectiveness. Microneedling is suggested as a possible complementary treatment.
community Topical Finasteride - Affordable options
The conversation discusses affordable options for topical Finasteride, including products like Morr F, 82F, and Essengen 6 Plus, with concerns about availability and cost. The user is seeking effective and convenient solutions, considering options like compounding pharmacies and homemade solutions.
community MY ANECDOTAL REPORT ON SAFETY OF ALFATRADIOL AND FLURIDIL COMBINED WITH FINASTERIDE! COMPOUNDS APPROVED FOR MPB IN THE EUROPEAN UNION (i cant comment on the efficacy, cause i am on other treatments)
The safety of combining alfatradiol and fluridil with finasteride as a potential treatment for male pattern baldness, which is approved in the European Union. Other treatments such as minoxidil and RU58841 were also discussed.
community pyrilutamide any results so far?
The hair loss treatment Pyrilutamide and whether it has had any results for users. Martinsahara is planning to buy some soon.
community Anyone tried herbal treatments like pumpkin seed oil etc. long enough to see it doesnt work?
Herbal treatments like pumpkin seed oil, saw palmetto, and rosemary oil showed little to no effectiveness for hair loss, with some users experiencing negative effects. Regular treatments like finasteride and minoxidil are suggested to be more effective, while vigorous scalp massage and low-level laser therapy (LLLT) might offer some benefits.
community finasteride vs "natural" DHT blockers
The conversation discusses challenges in obtaining finasteride in the Netherlands and explores alternatives like natural DHT blockers and topical finasteride. Suggestions include consulting different doctors or dermatologists and considering cost-effective options like cutting higher-dose tablets.
community Pelage have presented only phase 2a. The rest of phase 2 for PP405 will be presented at a later medical meeting
PP405's phase 2a trial results were presented, focusing on safety and pharmacokinetics, with a future meeting planned to share the full dataset. The trial includes a randomized controlled portion and an open-label extension, with no indication of phase 2B completion.
community What would you rank the most effective tool following mino, fin and dermarolling?
The conversation discusses various hair loss treatments, including minoxidil, finasteride, dutasteride, RU58841, microneedling, ketoconazole shampoo, and laser therapy. Users emphasize the importance of consistency, patience, and individual response to treatments.
community Most promising cures for baldness as of May 2026
PP405 is the most promising future treatment for hair loss, aiming to reactivate dormant hair follicles. Clascoterone 5% is the most promising near-term drug, while current strategies include using finasteride or dutasteride to stabilize hair loss and minoxidil to stimulate growth.
community What ever happened to pyrilutamide?
Pyrilutamide, a potentially effective hair loss treatment; other topical treatments like RU58841 and CB-03-01 that may have fewer side effects than Pyrilutamide; and the Phase 3 clinical trials of Pyrilutamide, which is likely to be approved by the FDA soon.
community Best carrier for pyrilutamide?
The conversation is about adding a low dose of pyrilutamide to a hair loss treatment regimen. Specific treatments mentioned include Minoxidil, finasteride, and RU58841.