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      community Shedding on pyri (KX-826) is this normal?

      in Update  9 upvotes 1 year ago
      A user experienced increased shedding after adding KX-826 to their long-term finasteride and minoxidil regimen. Another user reported mild side effects from KX-826, such as stomach and testicle pain.

      community Topical fin 0.025%, min 5% - 2,5 months progress

      in Finasteride/Dutasteride  9 upvotes 1 year ago
      The user started using topical finasteride 0.025% and minoxidil 5% twice daily, seeing initial improvement but later experiencing shedding and scalp pain. They are considering increasing the finasteride dose to 0.05% while using keto shampoo and dermarolling, and are debating the effectiveness of low versus standard doses of finasteride.

      community A Short Recap on PP405 and AAD 2026

      in Update 2 months ago
      PP405 is a promising experimental topical treatment for alopecia that reactivates dormant hair follicles by targeting cellular energy, with large-scale trials planned for 2026. While it shows potential, it cannot regenerate permanently destroyed follicles, making hair transplants the only guaranteed solution for advanced baldness currently.

      community Eucapil, Fluridil update from manufacturer

      in Treatment  5 upvotes 11 months ago
      The user is experiencing hair loss after a hair transplant and is considering using fluridil (Eucapil) and possibly alfatradiol as treatments, as they couldn't tolerate finasteride or minoxidil. The manufacturer of Eucapil confirmed they won't produce higher concentrations due to lack of efficacy.

      community ISO a topical without minoxidil

      in Finasteride/Dutasteride  3 upvotes 5 months ago
      A user seeks a topical hair loss treatment without minoxidil, considering options like finasteride, dutasteride, caffeine, tretinoin, or prostaglandin analogues. Recommendations include products like Strut, Maximus, Zeuss, and custom formulas from compounding pharmacies.

      community Source for topical valproic acid?

      in Chat  2 upvotes 6 months ago
      The conversation is about finding a source for topical valproic acid for hair regrowth. The user mentions PP405 and the unavailability of products from certain suppliers.

      community Looking for Affordable KX 826 Powder

      in Technology  6 upvotes 1 year ago
      The conversation is about finding an affordable source for KX 826 powder for hair loss treatment. One user mentions using it alongside dutasteride and minoxidil.

      community Throwing Fluridil (Eucapil) into the mix.

      in Product  7 upvotes 5 years ago
      A user named "tresslessinseattle" receiving a mysterious package of Eucapil hair loss treatment, which they are considering in combination with Minoxidil and Finasteride treatments to boost the regrowth they have been seeing.

      community Stabilized hairloss without sides (finally)

      in Finasteride/Dutasteride  20 upvotes 3 years ago
      User found hair loss stabilization without side effects using a topical solution of 0.008% Finasteride, 2% RU, and Stemoxydine. Other treatments like Eucapil, Fluridil, RU-monotherapy, and Pyrilutamide didn't work for them.

      community Any recent developments with Piloscopy?

      in Chat  3 upvotes 2 years ago
      Piloscopy's impact on hair loss treatment after 10 years remains unclear, and peppermint oil has shown to be effective, similar to minoxidil, in stopping recent hair loss. The user is considering dermarolling and has concerns about hair transplant scars.

      community Pyrilutamide solution question

      in Research/Science  8 upvotes 3 years ago
      The conversation is about the stability of pyrilutamide in different solutions. The user is asking if a 70/30 ethanol/pg solution with 4% water will degrade pyrilutamide.

      community i'm Considering adding hair stimulant: stemoxydine or alphatradiol

      in Treatment  5 upvotes 1 year ago
      The user is considering adding Stemoxydine to their hair loss regimen, as they already use topical finasteride with rosemary and cannot use Minoxidil. They are seeking feedback on Stemoxydine and Alphatradiol, and another user mentions 2-deoxy-d-ribose as a potential option.

      community Pyluritamide vs ru58841? Today’s opinion

      in Treatment  1 upvotes 6 months ago
      Pyluritamide and RU58841 are compared for effectiveness in addition to dutasteride for hair loss treatment. Reddit users report great results with RU58841, but data suggests pyluritamide may have better affinity.

      community Musely Classic Formula vs other options

      in Treatment  2 upvotes 5 months ago
      The conversation discusses using Musely's classic formula for hair loss, which includes minoxidil, dutasteride, tretinoin, ketoconazole, and hydrocortisone. Concerns are raised about hydrocortisone and the high concentration of dutasteride, with a preference for using research-backed concentrations without hydrocortisone.

      community Which Minoxidil solution should i use?

      in Minoxidil  7 upvotes 2 years ago
      The user is using Minoxidil 5% with procapil spray and oral Minoxidil 2.5mg daily, and plans to add finasteride 1mg. They accidentally ordered a Minoxidil solution with finasteride 0.1% and are seeking advice on which to use.

      community 6 months before and after pics: VDPHL01 (oral minoxidil)

      in Progress Pictures  111 upvotes 1 year ago
      A user shared their positive experience with a clinical trial for a new oral medication, VDPHL01, which is a reformulated version of oral minoxidil taken at a high dose of 17mg daily, showing significant hair regrowth after six months. The user noted that this formulation is believed to be more effective and time-released, with fewer side effects compared to regular oral minoxidil.

      community Thinking about RU58841

      in Treatment  4 upvotes 5 years ago
      OP experienced side effects from finasteride and is considering trying RU58841 for hair loss, while currently using minoxidil, Stemoxydine, a dermapen, and Nizoral. Another user shared positive results with RU58841, noting no side effects and maintained hair thickness after stopping its use.

      community Minoxidil + Tretinoin + Fexofenadine?

      in Minoxidil  1 upvotes 11 months ago
      The conversation discusses using Minoxidil with Tretinoin and Fexofenadine for hair loss. Some users doubt its effectiveness, noting Fexofenadine's unproven results for androgenetic alopecia.

      community Nanoxidil: a good substitute or a scam?

      in Treatment 1 year ago
      Nanoxidil is considered by some as a substitute for Minoxidil, but users report it as ineffective and expensive. Finasteride is recommended as a more effective treatment, often used with Minoxidil, microneedling, and ketoconazole.

      community Topical Finasteride: Update

      in Finasteride  63 upvotes 7 years ago
      A user applied a homemade topical finasteride solution daily for 35 days, reducing hair shedding significantly with minimal side effects. They plan to continue for 90 days and will provide further updates.

      community Fluridil solution at Actifolic

      in Treatment  4 upvotes 3 years ago
      Fluridil, also known as Topilutamide or Eucapil, is discussed as a treatment for hair loss. It is noted as an androgen receptor antagonist, not a vasodilator.

      community An Uncontrolled Case Series Using a Botanically Derived, β-Cyclodextrin Inclusion Complex in Two Androgenetic Alopecia-Affected Male Subjects

      in Research/Science  1 upvotes 5 years ago
      The conversation discusses a botanically derived treatment for androgenetic alopecia using ingredients like saw palmetto, green tea, and evening primrose, showing impressive results over 270 days. Concerns include the study's uncontrolled nature and potential product motivation, with suggestions to enhance absorption through derma rolling.

      community Actifolic RU58841 and others Scam?

      in Treatment  4 upvotes 3 years ago
      Actifolic's RU58841 and Pyri products are perceived as ineffective, with users reporting no side effects or improvements, suggesting possible quality issues. Users recommend alternative sources and emphasize the importance of timing when using RU58841 with Minoxidil.

      community Surprisingly thorough study on He-Shou-Wu/Fo Ti

      in Research/Science  14 upvotes 2 years ago
      He Shou Wu (Fo Ti) extract was found to prolong the hair growth phase, inhibit 5-alpha-reductase (like finasteride), reduce androgen receptors, and increase growth factors, potentially outperforming minoxidil in recovering hair follicle size after DHT exposure. Two compounds, emodin and TSG, are identified as responsible for these effects and warrant further investigation.

      community New study on TOPICAL pumpkin seed oil in mice

       6 upvotes 6 years ago
      The conversation discusses a new study on topical pumpkin seed oil for hair loss in mice. Treatments mentioned include Minoxidil, finasteride, and RU58841.