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      community making a clascoterone lotion from powder

      in Technology  2 upvotes 1 year ago
      A user is considering making a 2% clascoterone lotion from powder due to unavailability in their location. They plan to mix clascoterone powder with retinol lotion and use literature to determine the correct dosage.

      community Any male on topical spironolactone?

      in Research/Science  7 upvotes 4 months ago
      Topical spironolactone is discussed for hair loss treatment, with mentions of DIY solutions and dermatologist compounding. Users inquire about regrowth and sourcing the treatment.

      community RU58841 carrier - PG/Ethanol vs KB solution?

      in Treatment  2 upvotes 4 years ago
      The conversation discusses the differences between PG/Ethanol and KB solutions for RU58841 application, focusing on potential scalp irritation. KB solution is suggested for those allergic to PG, though both contain ethanol which can dry the scalp.

      community So is this the actual trial results for pp405?????

      in Research/Science  92 upvotes 1 month ago
      PP405 shows promising results for hair growth, potentially outperforming finasteride without side effects like erectile dysfunction. Users discuss using treatments like minoxidil, pyrilutamide, nizoral, and alfatradiol while waiting for PP405's availability.

      community Spiro for AGA in Europe

       5 upvotes 6 years ago
      Treatment options for female alopecia androgenetica, discussing the availability of spironolactone online in The Netherlands and other potential treatments like finasteride, minoxidil and RU58841.

      community Topical - Lantoprost .01%, MIN 10% DUT .05%, Hydrocortisone 1% Progrestron .025%

      in Treatment  6 upvotes 8 months ago
      A user was prescribed a topical treatment for hair loss including Latanoprost, Minoxidil, Dutasteride, Hydrocortisone, and Progesterone, after using an oral Minoxidil and Finasteride combo without significant results. Concerns were raised about the long-term use of hydrocortisone, with suggestions to consult a doctor regularly.

      community Better Than Minoxidil? Topical Sodium Valproate

      in Research/Science  50 upvotes 1 year ago
      Topical sodium valproate may promote hair growth by inhibiting GSK3β, allowing beta-catenin to proliferate, but it has potential side effects and requires more research. The conversation also mentions skepticism about a product called Vdphlo1, which includes sodium valproate and other ingredients.

      community Anagenic is trying to compound Gt20029

      in Treatment  55 upvotes 3 years ago
      The conversation discusses concerns that Anagenic's version of GT20029 might not be as effective or safe as Kintor's, with comparisons to issues faced by pyrilutamide. The chemical structure of the drug has been published.

      community Spironolactone Update

      in Female  10 upvotes 9 years ago
      A woman's experience with Spironolactone as treatment for female pattern hair loss, including the effects of increasing dosage and her doctor's recommendation to try finasteride if no results are seen after 6 months. Other users have also shared their experiences with using finasteride for this condition.

      community Clascoterone for hair loss. Promising study.

      in Treatment  11 upvotes 5 months ago
      A new topical medication, Clascoterone, shows promise for hair loss, improving hair count significantly. Trials for Breezula are ending, but sign-ups for PP405 trials are available for 2026.

      community PP405 - A True Breakthrough or Another Disappointment?

      in Research/Science  31 upvotes 10 months ago
      PP405 shows potential for hair growth, with 31% of advanced balding men experiencing over 20% increase in hair density in 8 weeks. However, skepticism persists due to selective data presentation and lack of long-term results, with comparisons to treatments like minoxidil and finasteride.

      community Korea launches 1st OTC hair loss drug

      in Treatment  29 upvotes 5 years ago
      Korea launched its first OTC oral hair loss drug, dexpanthenol B5. Users discuss its anti-oxidative and anti-inflammatory effects but note a lack of efficacy studies.

      community What are the alternatives to spironolactone for AGA?

      in Female  7 upvotes 1 year ago
      The user experienced side effects from spironolactone and is seeking alternatives for androgenetic alopecia (AGA), considering saw palmetto but unsure of its effectiveness. They are also exploring the possibility of using topical spironolactone, despite availability challenges.

      community Fluridil solution at Actifolic

      in Treatment  4 upvotes 3 years ago
      Fluridil, also known as Topilutamide or Eucapil, is discussed as a treatment for hair loss. It is noted as an androgen receptor antagonist, not a vasodilator.

      community Question about making a solution of RU58841

      in Treatment  1 upvotes 3 years ago
      The conversation is about making a solution of RU58841 using propanediol instead of propylene glycol due to skin irritation. The user seeks advice on whether this substitution is acceptable.

      community Does This Invalidate PP405 Completely?

      in Research/Science 2 months ago
      PP405's effectiveness in increasing hair density is questioned due to a small sample size, despite investment from Google Ventures. Users express skepticism and suggest waiting for more conclusive results.

      community Spironolactone for hair loss??

      in Product  6 upvotes 3 years ago
      Hair loss treatments discussed include Minoxidil, Finasteride, and Spironolactone. One user shares success with Finasteride, Minoxidil, and low-dose Cyproterone Acetate, but warns against long-term use of oral anti-androgens.

      community New molecule PP405 vs exercise

      in Research/Science  38 upvotes 1 year ago
      PP405 targets hair follicle stem cells differently than exercise-induced lactate, suggesting exercise alone may not replicate its benefits. Minoxidil and finasteride are recommended alongside exercise for hair regrowth, with additional suggestions like spicy food and infrared exposure.

      community where does the renewed spironolactone hype come from?

      in Research/Science  8 upvotes 3 years ago
      Topical spironolactone is gaining attention as an alternative hair loss treatment, but it's not as effective as other options like finasteride. Oral spironolactone can cause side effects in men, and there are better topical alternatives like RU, Pyril, and CB.

      community What do you think about this prescription

      in Treatment 2 years ago
      The user visited a trichologist due to ineffective topical finasteride treatment for hair loss. The trichologist recommended a new regimen including a two-month course of locoidon (cortisone 0.1%), followed by a solution containing minoxidil, hydrocortisone butirrate, estrone, progesterone, tocopherol acetate, trichosol, and transcutol.