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360-390 / 1000+ resultscommunity RU58841 and Dutasteride: How do they interact?
community Kintor stealing pictures from a hair transplant clinic to promote their failed product (KX826, Pyrilutamide)
Kintor is accused of using fake pictures to promote their product, Pyrilutamide (KX826), which failed Phase 3 trials. Users express disappointment and note similar false advertising has occurred with finasteride and minoxidil.
community I'm very skeptical about pyrilutamide
Pyrilutamide's effectiveness is questioned due to overstated claims and previous trial ineffectiveness, with some users opting for finasteride instead. Despite skepticism, some consider adding pyrilutamide to their regimen alongside treatments like bicalutamide.
community A better treatment would be a localized 5ar inhibitor that breaks down when it enters blood or leaves hair follicle
The conversation discusses the need for a localized 5-alpha reductase inhibitor that only affects the scalp without systemic side effects, similar to pyrilutamide's approach. Current treatments like topical liposomal finasteride and dutasteride are mentioned, but concerns about their systemic effects and lack of research are highlighted.
community PCOS hair loss - 6 months of topical minoxidil and dermarolling 0.5mm once a week (as well as biotin gummies)
A user shared progress pictures showing improvement in PCOS-related hair loss after six months of using topical minoxidil, dermarolling 0.5mm weekly, and taking biotin gummies. They expressed happiness about the appearance of new baby hairs.
community DUPA - 20 YO - Non responder to everything
A 20-year-old user experienced worsening hair loss despite using various treatments including topical and oral minoxidil, finasteride, and dutasteride. Other users suggested additional treatments like JAK inhibitors, RU58841, and lifestyle changes, but the user remains skeptical and frustrated.
community 2 months on topical finasteride + minoxidil + pyrilutamide
community Pyrilutamide six month update photos
A six month update of the users' experience with Pyrilutamide, a hair loss treatment that combines Minoxidil, Finasteride and RU58841.
community RU58841 is the only thing that worked for me, a DUPA sufferer
RU58841 slowed hair loss for a DUPA sufferer after other treatments like finasteride, dutasteride, and minoxidil failed. Some users reported side effects with RU58841, while others did not experience any.
community Pyrilutamide US Phase 2 Trial?
The Phase 2 trial for Pyrilutamide in the US, which started a year after the China trials, and inquiring about any available information on when it will finish. Treatments discussed include Minoxidil, Finasteride, and RU58841.
community topical minoxidil (5%) & kx826 (.5%) update.
The user has been using topical minoxidil (5%) for two years and kx826/pyrilutamide for one year, after experiencing side effects from finasteride. They report positive results from the combination of minoxidil and kx826 in combating hair loss.
community rudirect ru58841 seems bunk to me
RU58841 from rudirect caused more hair shedding and itch, while anageninc's RU58841 improved the situation. Users are concerned about the quality and authenticity of RU58841 from different suppliers, including those from China.
community Pyrilutamide - cosmetic vs. clinical trials
The conversation discusses the difference between the commercially available Pyrilutamide and the version in clinical trials. It also mentions treatments like Minoxidil, finasteride, and RU58841 for hair loss.
community I interviewed Kintor: GT20029 Clinical Trial Pictures. As well as KX826.
GT20029 and KX826 are promising hair loss treatments, with GT20029 increasing hair count and KX826 showing significant results. KX826 may be a good alternative for those who can't use finasteride or dutasteride, though results vary.
community If PP405 does revive "dead" hair follicles would DHT blockers theoretically be enough to maintain that new hair
PP405 may revive dormant hair follicles, and DHT blockers like finasteride or dutasteride could maintain new hair. Combining PP405 with minoxidil might be optimal, but long-term effects and continuous use are uncertain.
community Counter-update: Cbum's transplant DOESNT look super good now
Cbum's hair transplant is criticized for looking unnatural and not blending well, with some suggesting better results were expected given his resources. Discussions also cover the effects of steroids and finasteride on hair loss and muscle growth.
community Massive non stop shedding on and off fin (consistent for 2 months)
community Any other treatments to still be hopeful for?
The conversation discusses the potential of new hair loss treatments, with a focus on pyrilutamide, gt20029, and topical alfatradiol, and the possibility of improving their effectiveness through methods like increased concentration and microneedling. Dutasteride is also mentioned as a stronger option.
community Exalted Dutasteride master race
community 5ar alpha reductase stimulation is different depending on whether it’s type 1 or 2
The conversation discusses how different factors can stimulate type 1 and type 2 isoforms of 5-alpha reductase, which are enzymes linked to hair loss. Specific treatments mentioned include oral Dutasteride and topical Finasteride.
community Hair regrowth? Been noticing these tiny dots on my head where I apply 0.5 dut and 8% minox
User noticed tiny dots on their head after using 0.5% dutasteride and 8% minoxidil, which others identified as developing hair follicles. Encouragement was given to continue the treatment.
community Any help with female hair loss?
A 20-year-old female with PCOS is experiencing hair loss and excessive facial hair. She is using ketoconazole and caffeine shampoos, microneedling, and considering anti-androgens like finasteride, but is cautious about minoxidil due to facial hair concerns.
community Pelage Pharmaceuticals Announces Positive Phase 2a Clinical Trial Results for PP405 in Regenerative Hair Loss Therapy
Pelage Pharmaceuticals announced positive Phase 2a trial results for PP405 in hair loss therapy. The conversation discusses the delay in publishing full results and the need for further trials and approvals.
community Who is the ideal target for PP405? Will it render hair trasplants obsolete?
PP405 is being discussed as a potential treatment for hair loss, with uncertainty about its effectiveness compared to existing treatments like finasteride, dutasteride, and minoxidil. There is cautious optimism, but its impact on hair transplants remains unclear.
community Female 37/F - On Meds, but no progress. Add PRP?
community Finasteride, Dutasteride, Pyrilutamide, RU58841 all accomplish the same thing in your body. Why skip around?
Hair loss treatments Finasteride, Dutasteride, Pyrilutamide, and RU58841 have different mechanisms of action. They can be used individually or stacked for better protection against hair loss.
community (Serious) Updates and discussion, new treatments in development
Finasteride, minoxidil, and derma rolling are currently the best treatments for hair loss. New treatments like TDM-105795, GT20029, PP405, HMI 115, Tsuji, Scube 3, RU, JW0061, Topilutamide, and verteporfin show promise but have uncertain timelines.
community RU58841 vs. KX-826 vs. CB-03-01
community Updates on kintor’s pyrilutamide?
Hair loss discussion includes treatments Minoxidil, Finasteride, and RU58841. User seeks updates on topical treatment Pyrilutamide.