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      community day 107 of kx826 .5% . 1+ years on topical minoxidil.

      in Progress Pictures  18 upvotes 1 year ago
      The user has been using topical minoxidil for over a year and added kx826/pyrilutamide to improve hair growth, avoiding finasteride due to side effects like lowered libido and panic attacks. They report positive results with reduced shedding and healthier hair, particularly in areas previously unresponsive to minoxidil.

      community Losing Hair on Dutasteride? You might have LPP

      in Research/Science  100 upvotes 1 year ago
      Men with hair loss might have lichen planopilaris (LPP), which can mimic androgenetic alopecia, leading to misdiagnosis and ineffective treatment with finasteride or dutasteride. Proper diagnosis, including biopsies, is crucial to distinguish between androgenetic alopecia and conditions like LPP.

      community Another addition to the Hair loss equation.

      in Treatment  2 upvotes 2 years ago
      The post discusses various hair loss treatments including minoxidil, finasteride, microneedling, vitamins, lifestyle changes, and reducing prolactin levels. The user reports positive results after 4 months of treatment, including increased hair growth.

      community COQ10 + PQQ for scalp inflammation??

      in Chat  6 upvotes 2 years ago
      A 32-year-old male with diffuse thinning and seborrheic dermatitis has been using finasteride for 8 months without improvement. He is considering COQ10 + PQQ supplements for scalp inflammation and hair loss.
      Can liver problems be associated with response to the oral minoxidil?

      community Can liver problems be associated with response to the oral minoxidil?

      in Research  147 upvotes 5 months ago
      Liver problems may reduce the effectiveness of oral minoxidil due to impaired SULT1A1 enzyme activity, which is crucial for converting minoxidil to its active form. This reduction in enzyme function can significantly decrease the drug's effectiveness in promoting hair growth.

      community KX826 New Phase 3 Trial In China for 2025: 1.0% concentration

      in Research/Science  57 upvotes 1 year ago
      KX-826 is undergoing Phase III trials in China as a potential treatment for male pattern baldness, with some users considering it as an alternative or addition to finasteride and dutasteride. Opinions on its effectiveness vary, with some users reporting positive results and others finding it expensive and ineffective.

      community Better Than Minoxidil? Topical Sodium Valproate

      in Research/Science  53 upvotes 1 year ago
      Topical sodium valproate may promote hair growth by inhibiting GSK3β, allowing beta-catenin to proliferate, but it has potential side effects and requires more research. The conversation also mentions skepticism about a product called Vdphlo1, which includes sodium valproate and other ingredients.

      community Testing recommendations from lack of min/fin success

      in Research/Science  1 upvotes 5 months ago
      The user has been using minoxidil, finasteride, a laser cap, and ketoconazole shampoo for hair loss without success and is seeking advice on further tests or treatments. They have a family history of hair loss and have not yet undergone dermatologist or trichology tests.

      community I want to attempt to use the MPC inhibitor JXL-069

      in Research/Science  14 upvotes 1 year ago
      The conversation discusses skepticism about group buys for hair loss treatments, highlighting issues with unverified chemicals and the risks involved. It suggests stabilizing with dutasteride and minoxidil, and considering a hair transplant instead of experimenting with untested products.

      community Hair loss treatments rated (by gpt-4)

      in Research/Science  250 upvotes 3 years ago
      Rating treatments for hair loss, with the help of GPT-4, according to efficacy, evidence and tolerability; a combination of chemicals from research papers, custom compounds, and some suggestions from other users were included.

      community Totally confused by doctors opinions, would appreciate some clarity

      in Treatment  1 upvotes 1 year ago
      The user is experiencing hair loss and confusion over conflicting medical advice, with treatments including minoxidil, finasteride, and topical corticosteroids. They are unsure about the necessity of a biopsy and the timing of using minoxidil, while also considering the impact of potential androgenetic alopecia and telogen effluvium.

      community New molecule PP405 vs exercise

      in Research/Science  38 upvotes 1 year ago
      PP405 targets hair follicle stem cells differently than exercise-induced lactate, suggesting exercise alone may not replicate its benefits. Minoxidil and finasteride are recommended alongside exercise for hair regrowth, with additional suggestions like spicy food and infrared exposure.

      community Hair loss - The Root of the Problem

      in Hair Systems  2 upvotes 5 years ago
      Hair loss can be influenced by nutritional deficiencies, particularly low Vitamin D and fatty liver, and improving nutrition and lifestyle can strengthen hair. Treatments suggested include regular exercise, a balanced diet, vitamin supplements, and coconut oil massages, while acknowledging that hereditary factors may also play a role.

      community Gray market sources to get gt20029 or pp405?

      in Product  2 upvotes 1 year ago
      The conversation is about sourcing gray market compounds, gt20029 and pp405, for hair loss treatment. The user is interested in these compounds despite their unproven status and potential risks.

      community My hair transplant journey at Eugenix.

      in Update  138 upvotes 2 months ago
      A user shared their positive experience with a hair transplant at Eugenix in India, noting the professionalism and natural results. They mentioned using 2815 grafts and discussed the clinic's controversial name, but did not mention using specific treatments like Minoxidil or finasteride.

      community DHT Harms Scalp Microbiome: DHT Itch is REAL

      in Research/Science  416 upvotes 1 year ago
      Increased Malassezia and Cutibacterium in the scalp microbiome are linked to higher sebum production and inflammation in androgenetic alopecia (AGA). Treatments include ciclopirox shampoo, benzoyl peroxide shampoo, clobetasol propionate, calcipotriol, minoxidil, finasteride, and dutasteride.

      community Whats up with Prolactine these days?

      in Research/Science  20 upvotes 3 years ago
      The conversation discusses the potential role of prolactin in hair loss and mentions treatments like HMI115, mucuna pruriens, Zinc, and B6 P5P for lowering prolactin levels. It also touches on the use of natural compounds and the lack of studies due to funding issues.

      community Pelage Recruiting Now for Phase 2

      in Research/Science  11 upvotes 2 years ago
      Pelage is recruiting for phase 2 trials, showing promise for treating bald regions. The discussion highlights its potential effectiveness based on its mechanism of action.

      community Recent discovered thinning hair, taking steps to diagnose.

      in Chat  2 upvotes 7 months ago
      A 43-year-old noticed significant hair thinning and is using topical minoxidil, dermarolling, Alpecin, biotin, zinc, copper, vitamin D, and rosemary oil. They plan to see an endocrinologist and have blood tests scheduled to investigate further.