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      community 24M – aggressive shedding, past success with mesotherapy + minoxidil, now worse than before. Unsure if I should try a combo or consider a transplant.

      in Minoxidil  13 upvotes 6 months ago
      A 24-year-old is experiencing aggressive hair shedding despite past success with mesotherapy and minoxidil, and is considering adding treatments like Expecia, dermapen, or a hair transplant. Many suggest using finasteride to maintain hair, as it is necessary even after a transplant, and side effects are rare and reversible.

      community Finasteride affects both 5a reductase and 5b reductase

       6 upvotes 6 years ago
      Finasteride not only inactivates the 5a reductase enzyme but also affects the 5b reductase enzyme in a dose-dependent manner, which can impact sexual behavior and brain activity. The user experienced significant hair regrowth and side effects on 1mg of finasteride, which diminished after reducing the dose to 0.5mg, leading to no side effects and further hair improvement.

      community Wimpole Clinic 1850 grafts (23yo) Dr Malkani

      in Progress Pictures  123 upvotes 1 year ago
      A user shared their positive experience with a hair transplant at Wimpole Clinic, performed by Dr. Malkani, and discussed using finasteride at a reduced dose due to side effects. They also mentioned avoiding minoxidil due to heart pain and taking supplements like biotin, marine collagen, viviscal, and krill oil.

      community Having AGA as a girl makes me depressed

      in Female  65 upvotes 4 months ago
      A 20-year-old woman with androgenetic alopecia feels depressed about her hair loss, despite using topical minoxidil, spironolactone, and saw palmetto. Suggestions include trying oral minoxidil, higher doses of finasteride or dutasteride, and checking for vitamin deficiencies and heavy metal exposure.

      community VDPHL01 phase-2/3 results comparison

      in Research/Science  128 upvotes 2 months ago
      The conversation discusses hair loss treatments, focusing on a new slow-release oral minoxidil compared to topical minoxidil and finasteride. The results show that twice-daily dosing of the new treatment is slightly more effective than once-daily, but concerns about cost, side effects, and the accuracy of reported results remain.
      29M, Noticing More Scalp Visibility After 3 Years of Hair Shedding

      community 29M, Noticing More Scalp Visibility After 3 Years of Hair Shedding

      in General  68 upvotes 7 months ago
      The user noticed increased hair loss over the past three years and is seeking advice. A suggestion was made to consult a dermatologist or trichologist and consider blood tests, particularly for vitamin D levels, to address potential androgenetic alopecia (AGA).

      community Feedback on My Multi-Step Hair Loss Strategy at Age 27

      in Basic Questions  177 upvotes 2 months ago
      The user is considering continuing minoxidil and microneedling, possibly adding low-dose topical finasteride, and undergoing a large FUE hair transplant to improve hair appearance. They plan to use hair fibers for added density, aiming for a convincing cosmetic look rather than full density.

      community High testosterone and diffuse hairloss

      in Treatment  6 upvotes 5 years ago
      The user is experiencing diffuse hair loss due to high testosterone levels and has tried various treatments including finasteride, minoxidil, nanoxidil, keto/caffeine shampoo, dermarolling, and RU-58841 with limited success. They are seeking advice on safely lowering testosterone levels to manage hair loss.

      community 20% discount code at Anageninc

      in Chat  2 upvotes 1 year ago
      A discount code for 20% off at Anageninc is shared, valid for purchasing RU58841 or Pyri from May 10-11, 2025. The conversation focuses on hair loss treatments using RU58841.

      community Is PP405 formula available in grey market?

      in Treatment  16 upvotes 1 year ago
      The conversation is about the availability of the PP405 formula for hair loss treatment, with mentions of finasteride and its side effects. Users discuss the potential of obtaining the formula through unofficial channels and the challenges related to its genetic sequence and delivery method.

      community NW5 at 19. How many grafts do I need?

      in Transplants  138 upvotes 2 years ago
      A 19-year-old with rapid hair loss since 16 is considering a hair transplant but refuses to take finasteride or any 5α-Reductase inhibitors. They are currently using minoxidil, tretinoin, and microneedling with a Derminator 2, and only want hair until age 27.

      community 35% regrowth brothers and sisters! More effective than Minox and Fin?

      in Treatment  107 upvotes 7 years ago
      A double-blind clinical study that found ingestion of tocotrienols resulted in a 34.5% increase in hair regrowth compared to the placebo group, and discussion about potential side effects and cost of supplementation with vitamin E pills. The conversation noted that it may be more effective than commonly used treatments like minoxidil and finasteride.

      community DHT Gel (2.5%) to beard area + Dut + Pyri 1% + Minox

      in Research/Science  5 upvotes 9 months ago
      The conversation discusses using a combination of DHT gel, dutasteride, pyrilutamide, and minoxidil to promote beard growth while minimizing hair loss. Users suggest consulting a doctor and considering genetic factors before proceeding.

      community DUPA hair loss - What's the real deal ?

      in Research/Science  10 upvotes 3 years ago
      A 25-year-old male with DUPA (diffuse thinning including the donor area) has not seen improvement after 14 months on finasteride. He's considering switching to dutasteride (DUT) after advice from a hair loss YouTuber and is also contemplating trying RU58841.

      community SETIPIPRANT PGE2 GROUP BUY AND PIONEERING HAIR GROWTH

       6 upvotes 10 years ago
      The conversation is about a user seeking help with hair regrowth treatments, specifically mentioning Setipiprant, Minoxidil, Finasteride, and RU58841. The user is trying to contact forum members for guidance on making and using these treatments.

      community You would never even know - Matthew McConaughey

      in Chat  1370 upvotes 7 months ago
      Matthew McConaughey likely maintains his hair using finasteride, minoxidil, hair transplants, and possibly a hair system. Products like Reginix or rosemary oil are not considered as effective as these treatments.

      community Before and after pics with Microneedling + possible confounds

      in Progress Pictures  4 upvotes 5 years ago
      The user experienced hairline improvement using microneedling once a month with a 12-pin set at 1.5-2.0mm and taking Tru Niagen, alongside a heavily modified diet. They attribute the slow hairline improvement to environmental factors, particularly diet, rather than solely genetic factors.