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      community Effect of melatonin on aromatase expression

      in Update  5 upvotes 4 years ago
      Melatonin's effect on aromatase expression is unclear, with studies showing both increases and decreases. Hormonal impacts are complex and inconsistent, similar to changing health advice on other substances.

      community Am shedding more and more as I improved my routine

      in Treatment  1 upvotes 2 years ago
      The user is experiencing increased hair shedding and thinning despite using Minoxidil, Finasteride, vitamins, zinc, microneedling, and Omega 3 supplements. They are seeking advice on whether this is normal and how to stop it.

      community TRT. Pyrilutamide. Ru58841. Help

      in Treatment  3 upvotes 2 years ago
      A 30-year-old man experienced significant hair loss after starting testosterone replacement therapy (TRT), which did not improve with daily finasteride and minoxidil. He is considering restarting TRT and is seeking advice on using pyrilutamide or RU58841 to prevent further hair loss.

      community Bloodwork after 8 months on finasteride, is this normal?

      in Update  27 upvotes 2 years ago
      A user on finasteride for 8 months shared bloodwork results showing increased testosterone and estradiol levels, with concerns about high LH. Responses advised monitoring for symptoms but noted levels are within reference ranges.

      community Please critique my regimen, gentle approach oral/topical

      in Treatment  1 upvotes 2 years ago
      The user is taking 0.5mg finasteride and 0.5mg Loniten orally daily, using Eucapil twice weekly, and Minoxidil foam once daily for hair loss. They believe Eucapil effectively stops hair loss despite side effects like breast growth.

      community Can rosemary oil cause gynaecomastia?

      in Microneedling 1 year ago
      A user is concerned that using rosemary oil after microneedling might cause gynaecomastia due to increased absorption and potential DHT blocking. Other users believe rosemary oil is unlikely to affect hormones or cause gynaecomastia.

      community Prolonged shedding over last 15 months

      in Update  2 upvotes 4 months ago
      The user has been experiencing prolonged hair shedding despite using Dutasteride, Minoxidil, and topical Finasteride, with blood tests showing high free testosterone and low SHBG. Suggestions include adjusting Minoxidil dosage, considering topical anti-androgens like RU58841, and addressing metabolic factors to increase SHBG.

      community lost all my gains switching from liquid to foam

       5 upvotes 7 years ago
      Switching from liquid to foam minoxidil led to hair loss for OP, possibly due to a second shedding cycle. OP experienced allergic reactions to propylene glycol in the liquid form, causing dandruff and itchiness, which improved after switching to foam.

      community CTE and lots of shedding for over a year

      in Female  5 upvotes 2 years ago
      A female user has experienced severe hair shedding since stopping birth control in late 2022, diagnosed as telogen effluvium with no signs of androgenetic alopecia. Despite healthy living and optimal bloodwork, she continues to shed hair daily but also sees significant regrowth.

      community Can't help but feel somethings wrong (MtF 18)

      in Transgender  4 upvotes 2 months ago
      The user is experiencing hair loss and is using treatments like finasteride, minoxidil, and hormone replacement therapy (estradiol enanthate injections) to address it. They are advised to be patient with the treatments and consider using a dermapen for microneedling.

      community My detailed 5-month topical finasteride experience

      in Finasteride/Dutasteride  5 upvotes 1 year ago
      A user shared their 5-month experience using topical finasteride for hair loss, noting side effects like watery semen and puffy nipples, which led them to stop the treatment. They saw no significant hair improvement and have since switched to using minoxidil.

      community minoxidil and finasteride 3 months in

      in Progress Pictures  137 upvotes 1 year ago
      The user has been using topical minoxidil and oral finasteride for three months with visible hair thickening and no side effects. Another user mentioned experiencing watery semen and headaches with finasteride, and plans to add derma rolling and oils to their routine.

      community Feel like im not making process. Had insane shed. (Min/Fin/HRT)

      in Progress Pictures  5 upvotes 2 months ago
      The user started using oral minoxidil and estradiol in August 2025, added finasteride in December, and experienced significant hair shedding in February/March. They switched to estradiol injections and are considering their hair washing routine, while another user suggested consulting a dermatologist and possibly trying dutasteride.

      community A reminder that Telogen Effluvium could look like MPB; my progress

      in Progress Pictures  30 upvotes 3 years ago
      A 19-year-old male experienced significant hair loss, initially thought to be male pattern baldness (MPB), and used minoxidil and briefly finasteride. After realizing the issue was telogen effluvium (TE), he improved his diet and supplemented with vitamins, which led to substantial hair regrowth.

      community Oral Minoxidil Secret Very important

      in Minoxidil  237 upvotes 11 months ago
      Oral minoxidil can cause side effects like shortness of breath and constipation, which may be reduced by taking it in the morning. Some users experience no side effects, while others switch to topical treatments or adjust their dosage and timing to manage symptoms.

      community HRT is literal black magic. Fin 1 mg/day @ 4 years, min 2x/day @ 3 years, Estradiol 4mg/day @ 3.5 months, and Spironolactone 100mg/day @ 3.5 months (estra & spiro are medicines you should likely not take if you are a cis man)

      in Progress Pictures  118 upvotes 1 year ago
      User shared progress on hair regrowth using Fin 1 mg/day for 4 years, Min 2x/day for 3 years, Estradiol 4mg/day, and Spironolactone 100mg/day for 3.5 months. They noted significant hairline recovery and advised against HRT for cis men due to feminizing effects.

      community 19F, hair loss. How to cope? [x-post /r/Haircarescience]

       10 upvotes 11 years ago
      A 19-year-old female is experiencing significant hair loss, with symptoms including alternating hair colors and thinning body hair. She seeks advice on coping and potential treatments, with suggestions to consult a dermatologist and check thyroid and hormone levels.

      community Anyone else a non-responder to spiro?

      in Treatments  63 upvotes 1 year ago
      The conversation discusses hair loss treatments, specifically mentioning Spiro, Min, Fin, and RU. It highlights that Spiro is generally for women and can affect men's hormonal balance.

      community is there anything that stops hair loss?

      in Female  6 upvotes 1 year ago
      A user is experiencing rapid hair loss and has been diagnosed with telogen effluvium by multiple dermatologists, but doubts the diagnosis due to the severity and speed of the hair loss. They are considering various treatments like spironolactone, estradiol, and possibly finasteride, while also exploring the possibility of hormonal imbalances or autoimmune issues.