PP405 increased hair density by 20% in 31% of participants, but results are considered underwhelming. Minoxidil and finasteride are seen as more effective treatments.
The conversation is about using oral finasteride and minoxidil for hair loss, with consideration of adding topical GHK-Cu for skin and hair benefits. The user seeks opinions on this combination.
The conversation discusses how the absorption rate of topical finasteride varies and is not equivalent to its oral form, with only a small percentage reaching the scalp. It also mentions that minoxidil in high concentrations is used topically because only a small amount is absorbed.
The conversation discusses using RU58841 with octopirox or essential oils for hair loss treatment. The user is seeking advice on which variation to try.
The conversation is about BosleyMD Revive+ Serum, which uses Y100 Compound instead of Minoxidil. The user is seeking reviews or opinions on this newer product.
The user noticed increased hair fullness after using a minoxidil and finasteride oral capsule but is unsure if the 1.25 mg minoxidil dose is sufficient. They are considering switching to a higher dose and are waiting for a dermatologist's advice.
A pharmacy error resulted in a finasteride solution being 100 times stronger than prescribed, not 10,000 times as initially feared. OP is advised to contact the pharmacy to clarify the preparation before traveling.
A user was prescribed a topical solution containing 10% Minoxidil and 0.1% Finasteride for hair loss. They are seeking experiences with these dosage levels.
The new formulation includes minoxidil, finasteride, redensyl, caffeine, and propacil, and removes alcohol. The user is concerned about potential hair shedding due to the change in ingredients.
The user added RU58841 to their finasteride and minoxidil routine, noticing significant improvement in hairline after 52 days. Some users warn about potential side effects of RU58841, while others express curiosity and congratulate the progress.
Taking zinc and copper may offset copper depletion and potentially aid hair health when used with finasteride. The user is considering whether to use these supplements alongside finasteride or wait until switching to dutasteride.
RU58841 lacks FDA approval due to financial and safety concerns, including potential cardiological side effects. The company abandoned further research, and users report adverse effects like heart palpitations and gynecomastia.
Visible hair improvement after 10 weeks using minoxidil, estradiol enanthate, acetophenide algestone, and bicalutamide. The user is a 25-year-old male with reduced testosterone levels, expressing a preference for less masculinity.
The user has been using finasteride and minoxidil since October 2023 and is concerned if a supplement containing L-arginine, L-citrulline, Tongkat Ali, Tribulus terrestris, Avena Sativa, Gingko Biloba, Ginseng, Pyridoxine, Zinc Gluconate, and Saw Palmetto can cause hair loss. They report thicker and denser hair despite ongoing shedding.
A user ingested RU58841 orally and experienced severe heart and breathing issues, requiring emergency medical assistance. They concluded that MV supplements is a legitimate supplier but warned of the serious side effects.
Pelage plans to conduct two Phase 3 trials for PP405, a new hair loss treatment, which may take about a year to complete. Users discuss various hair loss treatments, including pyrilutamide, minoxidil, finasteride, and clascoterone, with some expressing impatience over the lengthy trial process compared to faster drug approvals like the COVID vaccine.
A user has been using 1mg oral finasteride and 5% topical minoxidil for six months, with some derma stamping, but feels hair growth has stagnated and is considering PRP or a hair transplant. Others advise continuing the current regimen, noting that maintaining existing hair is an achievement, and suggest ignoring negative comments from friends.
Azelaic acid is discussed for its anti-inflammatory and anti-fungal properties, which can improve scalp health and potentially boost hair growth. It is suggested for topical use, especially alongside minoxidil.
The conversation is about someone considering using CB-03-01 for hair loss but has ordered finasteride, which they are hesitant to use. They are seeking advice on how to prepare CB-03-01 from powder form and the appropriate strength to use.
There is no new information on pp405, with data collection expected to finish by the end of 2025. Users are discussing the timeline for data analysis and completion of Pelage Pharmaceuticals' phase 2 study.
The user experienced hair regrowth over four months using 5% topical minoxidil, oral biotin, and saw palmetto. They also use rosemary and mint conditioner and biotin shampoo.
Combining finasteride with minoxidil and tretinoin is discussed, with concerns about potential overdose. It is suggested that high doses of finasteride do not provide additional benefits beyond 1 mg.
PP405 is a potential new hair loss treatment that works through metabolic pathways rather than hormonal ones, with an estimated market release between late 2027 and 2029. Current alternatives to finasteride include minoxidil, pyralutamide, fluridil, and RU58841, with hair transplants also being a viable option.
The user is using Minoxidil 5% with procapil spray and oral Minoxidil 2.5mg daily, and plans to add finasteride 1mg. They accidentally ordered a Minoxidil solution with finasteride 0.1% and are seeking advice on which to use.
The user has been using finasteride for six months to address hair loss and is considering adding minoxidil to improve hair thickness. They are also using microneedling, peppermint oil, saw palmetto, biotin, and vitamin D supplements.
Rhamnose may promote hair growth and pigmentation, suggesting it as a potential hair loss treatment. The conversation discusses its potential alongside known treatments like Minoxidil, finasteride, and RU58841.