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      community Mechanism of action of alfatradiol (17 alpha estradiol)

      in Research/Science  5 upvotes 2 years ago
      The conversation discusses the mechanism of action of alfatradiol (17 alpha estradiol) in treating hair loss. It explores theories that it either inhibits 5 alpha reductase to prevent T->DHT conversion or aromatizes scalp T into 17-alpha-estradiol to save hair.

      community Anyone here going the “natural” route?

      in Scalp Massage  48 upvotes 3 years ago
      People discussing their experiences with natural treatments for hair loss, such as essential oils, deep scalp massages, anti-inflammatory measures, and supplements. Most of the replies suggest that these treatments are not effective and recommend medication such as minoxidil or finasteride instead.

      community Dim: high estradiol levels what to do

      in Chat  8 upvotes 1 year ago
      A user is experiencing facial bloating from low-dose topical finasteride due to high estradiol levels and is seeking advice on using DIM to manage this issue, including dosage and brand recommendations.

      community What do you mix your RU58841 powder with?

      in Product  1 upvotes 1 year ago
      RU58841 powder is mixed with a 70% ethanol and 30% propylene glycol solution, with some users seeking PG-free alternatives. Minoxidil is also mentioned as a treatment option.

      community MSM for regrowth???

      in Question  2 upvotes 7 years ago
      MSM is discussed as a potential treatment for hair regrowth, with mixed opinions on its effectiveness. Some users report faster hair and nail growth, while others question its credibility due to lack of scientific evidence.

      community Topical Saw Palmetto: An Alternative to Microdosing Topical Finasteride?

      in Product  17 upvotes 3 years ago
      The user is exploring topical Saw Palmetto as a milder alternative to microdosing topical Finasteride for hair loss, aiming to minimize systemic DHT impact. They plan to experiment with this herbal remedy for a year to assess its effectiveness on their mild androgenetic alopecia without significant side effects.

      community Notice any progress?

      in Question  5 upvotes 7 years ago
      A 23-year-old is using finasteride, minoxidil, nizoral, a dermapen, rosemary oil, and peppermint oil for hair loss treatment. They are seeking feedback on their progress.

      community what's an effective natural dht blocker other than fin?

      in Chat  4 upvotes 4 years ago
      Curcumin, found in turmeric, may reduce DHT levels and hair loss, similar to finasteride, but without its side effects. However, natural DHT blockers are generally considered too weak to make a significant difference in hair loss.

      community Predicted Breezula format? (liquid/cream/foam etc)

      in Treatment  10 upvotes 6 years ago
      The conversation is about the potential format of Breezula, a hair loss treatment, and concerns that it might be greasy or sticky. Specific treatments mentioned are Minoxidil, finasteride, and RU58841.
      Lost and need help

      community Lost and need help

      in General  156 upvotes 1 year ago
      A 15-year-old is experiencing hair loss and has tried rosemary and jojoba oils without success. They are advised to see a doctor for thyroid and androgen tests and consider using Minoxidil.

      community Why are there no FDA approved NSAA's yet?

      in Research/Science 2 years ago
      The conversation discusses why there are no FDA-approved NSAAs like RU58841 on the market, despite their potential superiority to 5AR inhibitors like finasteride. It explores the effectiveness of treatments like Minoxidil, finasteride, and RU58841 for hair loss.

      community Doc suggested to start using Fin

      in Treatment  179 upvotes 2 years ago
      A user is seeking advice on hair loss treatment and has been prescribed finasteride. They currently use minoxidil, rosemary oil, and castor oil, and are considering adding dermarolling. Respondents suggest daily use of minoxidil and finasteride, with some recommending additional treatments like ketoconazole shampoo, dermapen, dutasteride, and vitamins.

      community Adipose tissue layer and stem cells.

      in Research/Science  4 upvotes 8 months ago
      Adipose fat cells and stem cells may help treat hair loss by restoring the scalp's thickness. Treatments like NanoFat injections and Botox are discussed for their potential to promote hair growth.

      community What's the deal with Zinc and DHT?

      in Chat  48 upvotes 2 years ago
      The conversation discusses the conflicting information about Zinc's effect on DHT and its role in hair loss. It mentions that Zinc can act as a 5AR inhibitor at high doses but may increase DHT if taken to correct a deficiency, and highlights the importance of nutritional balance for hair health.

      community pyrilutamide solution progress log

      in Product  20 upvotes 3 years ago
      A 28 year old using a hair loss prevention protocol to restore thinning hair, which includes finasteride, dutasteride, minoxidil, stemoxydine, alopecin, nizoral shampoo and microneedling; the user is now adding pyrilutamide solution to the regimen with the hope of improving their results. RU58841 was also ordered but not yet used.

      community Now vs 3 months ago👍keep going guys!

      in Progress Pictures  14 upvotes 2 years ago
      The user shared progress pictures showing hair improvement over three months using topical minoxidil twice a day, rosemary oil, pumpkin seed oil, a dermaroller once a week, and rosemary shampoo. The post encourages others to keep going with their treatments.

      community Sensitive to Oral fin + RU. Am I screwed?

      in Product  5 upvotes 4 years ago
      Akinfenrawr experienced negative side effects from oral finasteride and RU58841, and is seeking alternative hair loss treatments. They discuss various options, including raloxifene, oral dutasteride, liposomal finasteride, Breezula, Pyrilutamide, SM04554, and sulforaphane, but have concerns about efficacy, availability, and cost.

      community Any clinical study on cysteine alone for hair loss?

      in Research/Science  5 upvotes 1 year ago
      The conversation discusses the lack of clinical studies on cysteine alone for hair loss, with the original poster already using medications like Minoxidil and finasteride. Suggestions include trying 2ddr as a growth stimulant, though concerns about side effects like gas are mentioned.