PP405, a topical LDH inhibitor, has shown to stimulate hairfollicle stem cell proliferation in humans with moderate hair loss. They are advancing to more detailed trials this year.
HMI 115 did not work as expected for hair regrowth in humans, unlike in macaque monkeys. There is anticipation for further research on prolactin's role in hair loss, with expectations that pharmaceutical companies will likely solve this before universities.
The conversation is about hair regrowth progress using topical finasteride and minoxidil twice daily, with occasional microneedling. The user also uses Minoxidilmax and WOW Skin Science Apple Cider Vinegar Shampoo.
PP405, developed by Pelage Pharmaceuticals, can reactivate dormant hairfollicle stem cells and increase hair growth by 20% in eight weeks, unlike minoxidil or finasteride. However, skepticism remains about its effectiveness and availability, with concerns about funding and the timeline for broader access.
The user experienced significant hairline regrowth over seven months using oral finasteride, topical minoxidil, and microneedling. Initial shedding occurred, but baby hairs appeared around three months, gradually maturing to fill in the hairline.
A user, 35M, has been using oral finasteride for 5 years and 5% minoxidil for 3 years, which stopped hair loss but didn't promote regrowth. After starting RU58841 5 months ago, they noticed long, translucent hairs and are asking if these hairs will darken and how to encourage this.
A user who underwent a hair transplant in their twenties and are now discussing the best treatments for long-term management of hair loss, such as finasteride and Minoxidil, as well as potential alternative treatment options like RU58841.
The conversation discusses hair regrowth, with users sharing experiences and advice on using finasteride, minoxidil, and dermarolling to stimulate hair growth. Many users report seeing small hairs, which they consider a positive sign, though opinions vary on whether these hairs will develop into thicker, terminal hairs.
ABS-201 shows promise for male hair regrowth by blocking the prolactin receptor, with higher expected efficacy than current treatments. The discussion also covers dosing differences between macaques and humans for hmi115, highlighting a significant dosage disparity.
A 35-year-old MTF individual shared their hair recovery journey, using Minoxidil, Dutasteride, Estradiol, Spironolactone, Microneedling, and Exosomes. They recently had a hair transplant and are documenting the healing process.
The user started oral minoxidil and finasteride two months after a hair transplant and plans to switch to dutasteride, using Nizoral and Mossi shampoos. They are considering a second transplant in Tijuana and using hair fibers and mousse for styling while waiting for medication effects.
The user is using Minoxidil, Finasteride, RLLT, Nizoral Shampoo, and microneedling for hair regrowth. They notice some thickening and new hair growth, especially in the front, but are unsure about the overall regrowth due to previous head shaving and photo comparisons.
The user discusses their experience with hair loss despite taking estrogen and cyproterone, and estimates needing around 3000 grafts for a feminine hairline. They are considering getting the procedure done in Turkey due to high European costs.
A breakthrough in hairfollicle cultivation using induced pluripotent stem cells (iPSCs) has been achieved, producing large hairfollicles suitable for transplantation. Clinical trials for this hair multiplication technology are planned in partnership with Yinguan Biotechnology.
User experiences slow hair regrowth despite using finasteride, topical minoxidil, and supplements like biotin, zinc, and collagen. They seek advice on addressing overall slow hair regrowth.
The user reports hair regrowth after 15 weeks using oral finasteride, topical minoxidil, oral pumpkin seed oil, and ketoconazole shampoo. Images show progress before and after treatment.
Methods of treating hair loss, such as using Minoxidil and Finasteride, as well as the potential use of RU58841. People have shared their experiences with these treatments, discussing the success of them in aiding hair growth.
The conversation is about hair regrowth using topical finasteride, minoxidil, and microneedling, with some users noticing new hair growth. The original poster also takes protein, biotin, and vitamin D supplements and prefers topical treatments due to concerns about side effects from oral finasteride.
Hairfollicle cloning is claimed to be possible but not widely available due to potential safety issues, such as cancer risks. Current treatments like finasteride and dutasteride are not effective for everyone, and there is frustration over limited access to these medications.
PP405 shows promise for hair regrowth, with new hairs observed in 66% of patients in just 27 days. The discussion also mentions Minoxidil, finasteride, and RU58841 as potential treatments.
The conversation is about someone's improvement in hair density and hairline appearance after consistently using finasteride, topical minoxidil, dermarolling, and ketoconazole. They shared a progress picture showing the best results they've seen since starting treatment.
The post discusses a hair loss treatment regimen including oral finasteride, topical minoxidil, a rejuvenating scalp serum with caffeine, rosemary, and ginger, topical ketoconazole, saw palmetto, and derma rolling. The user seeks advice for scalp pimples and irritation.
Hair fibers impressively cover bald spots, boosting confidence. User started big 3 treatment (0.5mg fin, 1 time minoxidil 5% topical, ketoconazole 2%) for regrowth.
Hair regrowth progress using finasteride, minoxidil, and dermarolling. Visible improvements started around month 6, with initial shedding from minoxidil.
MCL-1 is important for hairfollicle stem cell survival, but its impact on human hair regrowth is unclear. Minoxidil and finasteride are the main treatments, with doubts about new discoveries leading to effective human solutions soon.
A 25-year-old shares progress on hair regrowth using finasteride, ketoconazole shampoo, Alpecin caffeine shampoo, and topical minoxidil, noting improved hair health but persistent temple thinning. They consider switching to oral minoxidil, adding microneedling, and possibly a hair transplant after one year.
FluffyyKoala shared their 6-month hair regrowth journey using finasteride, minoxidil, and microneedling, with positive results and minimal side effects. Others in the conversation shared their experiences, asked questions, and congratulated FluffyyKoala on their progress.