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      community Follow up appointment with Donovan.

      in Finasteride/Dutasteride  17 upvotes 2 years ago
      The user was diagnosed with DUPA and initially treated with finasteride, then switched to dutasteride which worsened their hair loss. They are now returning to finasteride and adding treatments including oral minoxidil, Proscar, Viviscal, pumpkin seed oil, LLLT, and Nizoral shampoo, hoping for hair regrowth.

      community Verteporfin test long term results

      in Treatment  15 upvotes 3 years ago
      Testing the effectiveness of Verteporfin as a potential treatment for hair loss, with users discussing their thoughts on its long-term results. Treatments mentioned include Minoxidil, Finasteride, and RU58841.

      community FOR PYRILUTAMIDE NON-BELIEVERS (progress album, 14 months)

      in Progress Pictures  28 upvotes 2 years ago
      A user shared their 14-month progress using Pyrilutamide and Minoxidil for hair loss, noting improvement and no side effects with these treatments, unlike their negative experiences with Finasteride and RU58841. They emphasized the importance of consistent application for seeing results.

      community Hair loss research is a money grab

      in Chat  226 upvotes 5 months ago
      Hair loss is linked to DHT, with treatments like finasteride and minoxidil being common but not definitive. Economic interests influence research, and there is potential for new treatments like PP405 and RU58841.

      community Caffeine & Alopecia: What the Science Seems to Say

      in Research/Science  18 upvotes 2 years ago
      The conversation discusses the potential benefits of topical caffeine for Androgenetic Alopecia (APA) and female pattern hair loss. While some studies suggest positive results, there's no reliable scientific evidence to strongly recommend caffeine compounds for hair regrowth.

      community Any good experiences with Alfatradiol ?

      in Treatment  4 upvotes 5 years ago
      Alfatradiol is discussed as a weak 5ARI and estrogen, not as effective as minoxidil, RU58841, or CB-03-01, but a safe alternative for those who can't use finasteride. Users express frustration over the lack of strong FDA-approved topical antiandrogens for hair loss.

      community Pyrilutamide stopping Minoxidil gains

      in Chat  2 upvotes 2 years ago
      Pyrilutamide is seen as effective for maintaining hair without regrowth, while Minoxidil is known for growing new hair but causes shedding of old hairs. There is a question if using Pyrilutamide would inhibit the hair regrowth effects of Minoxidil.

      community RU58841 - How & When to Apply?

      in Product  5 upvotes 2 years ago
      RU58841 should be applied directly to the scalp, ideally once a day, a few hours before bed. Some users experienced side effects like shedding and systemic issues when using RU58841 and Minoxidil together, while others reported no side effects when using RU58841 alone.

      community Concerns about CosmeRNA safety mechanisms

      in Treatment  3 upvotes 3 years ago
      Concerns about CosmeRNA safety mechanisms and potential side effects. Discussion includes comparisons to Fluridil and questions about nanoparticle specificity and siRNA stability.

      community Is RU58841 or pyrilutamide a stronger topical anti-androgen?

      in Treatment  3 upvotes 2 months ago
      The conversation discusses adding either RU58841 or pyrilutamide to a hair loss treatment regimen that already includes oral dutasteride and oral minoxidil. RU58841 is considered the stronger anti-androgen but may have more side effects.

      community There is news from pyrilutamide?

      in Product  32 upvotes 2 years ago
      The discussion is about a hair loss drug called pyrilutamide. Users discuss its efficacy, safety, and expected market release around 2025-2026, with some expressing concerns about the authenticity of current market offerings.

      community Chances GT20029 releases by 2028?

      in Technology  7 upvotes 2 years ago
      The conversation is about hair loss treatments, specifically the anticipation for the release of a new treatment, GT20029, by 2028. Users are discussing their experiences with current treatments like finasteride and dutasteride, and the potential of future treatments, including FAK inhibitors and verteporfin trials.

      community Has anyone tried Topical oxytocin?

      in Treatment 2 years ago
      A user reported less hair shedding using melatonin spray and is considering trying topical oxytocin or estrogel for hair growth, but is concerned about potential side effects like breast development. Topical oxytocin has been found to promote hair growth by increasing growth factors.

      community 14 Months Dut/Minox/Microneedling + 13 Months HRT

      in Transgender  36 upvotes 2 weeks ago
      The user shared their hair regrowth journey using treatments like dutasteride, minoxidil, microneedling, tretinoin, Nizoral, silica, biotin, and hormone replacement therapy (HRT) with cyproterone and estradiol. They reported substantial hairline improvement and some crown thinning, with hopes for further progress.

      community The hardest hair protocol ever!

      in Research/Science  10 upvotes 3 years ago
      The user is using RU58841, finasteride, dutasteride, and minoxidil to slow down aggressive hair loss but is still experiencing hair shedding due to high testosterone levels. They plan to use ostarine to lower testosterone and prevent hair loss while maintaining muscle mass, and will continue using the other treatments.

      community 6 month transformation from fin to dut+min+ru

      in Progress Pictures  102 upvotes 4 months ago
      A 30-year-old male switched from finasteride to a combination of dutasteride, oral minoxidil, and RU58841, achieving significant hair growth without side effects. He plans to add GHK-Cu peptide to his regimen for further improvement.

      community Trans: Do I need to use Finnasteride?

      in Transgender 2 years ago
      A transgender individual is starting spironolactone and estradiol for hormone replacement therapy (HRT) and is considering adding finasteride to help with hair loss. They are also planning to use minoxidil and microneedle, but are unsure if they need to use another anti-androgen or more aggressive treatments. A respondent advises against using pyri and suggests waiting to see if the HRT alone is sufficient before becoming dependent on minoxidil.

      community Having AGA as a girl makes me depressed

      in Female  67 upvotes 2 months ago
      A 20-year-old woman with androgenetic alopecia feels depressed about her hair loss, despite using topical minoxidil, spironolactone, and saw palmetto. Suggestions include trying oral minoxidil, higher doses of finasteride or dutasteride, and checking for vitamin deficiencies and heavy metal exposure.

      community Added Tretinoin to my my routine and am shedding like crazy.

      in Treatment  1 upvotes 1 year ago
      The user has been using finasteride and minoxidil for almost 2 years with maintenance but no significant regrowth. After adding tretinoin 2 weeks ago, they experienced increased shedding and are seeking advice on whether this is a positive sign.