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      community Today was Last update on pp405

      in Research/Science  109 upvotes 9 months ago
      A new hair loss treatment, PP405, is moving from phase 2A to 2B in clinical trials, sparking discussions about its potential to regrow dormant hairs and its impact on existing treatments like Minoxidil and finasteride. Some users express skepticism, while others are hopeful about its future effectiveness.

      community Pyrilutamide for 16 weeks, with some progress

      in Progress Pictures  40 upvotes 2 years ago
      User gained hair with topical minoxidil and finasteride, then experienced shedding after starting pyrilutamide. After 12 weeks, new hairs grew and existing hairs thickened, hoping for more improvement in a year.

      community Is this regrowth? ketoconazole

      in Is this regrowth?  13 upvotes 11 months ago
      The conversation is about hair regrowth treatments, including ketoconazole, vitamins, fish oil, collagen, pumpkin seed oil, rosemary, and dermal rolling. Users suggest trying finasteride and intense weight training to enhance results.
      20M with Crown Thinning: Minoxidil/Finasteride Shedding Concerns

      community 20M with Crown Thinning: Minoxidil/Finasteride Shedding Concerns

      in General  110 upvotes 7 months ago
      A 20-year-old experiencing crown thinning is using a topical minoxidil/finasteride treatment and is concerned about shedding. Shedding is common and temporary, lasting weeks to months, and it's advised to continue the treatment as results can take up to a year.

      community My summation of PP405 - looks promising

      in Research/Science  209 upvotes 1 year ago
      PP405 shows promise for hair regrowth by manipulating stem cell characteristics and lactate dehydrogenase, with Phase 2a trials pending. Google Ventures' $15M investment suggests confidence, but results and market availability remain uncertain.

      community How is no one talking about this?

      in Treatment  5 upvotes 1 year ago
      Bovine colostrum is being discussed for its potential in hair regeneration, with some users noting that oral consumption may not be effective due to stomach acid destroying exosomes. The conversation also touches on ethical concerns about sourcing colostrum.

      community Welp - pp405 conference showed nothing

      in Update  80 upvotes 3 weeks ago
      PP405 shows potential for hair growth by increasing terminal hair and converting vellus hairs, but results are modest and more waiting is needed. It complements existing treatments like minoxidil and finasteride, but won't replace them.

      community ~ 4 months progress so far, hoping it gets better

      in Is this regrowth?  68 upvotes 6 months ago
      The user experienced significant hair regrowth after 4 months using oral minoxidil, oral dutasteride, topical minoxidil, Nizoral shampoo, microneedling, and various supplements. They reported increased body hair and some acne as side effects but noticed less hair breakage with silk pillows.

      community The Ordinary hair serum / Redensyl / Taxifolin initial experiences

       2 upvotes 6 years ago
      A user shared their initial experiences with The Ordinary hair density serum, which contains Redensyl (taxifolin). They observed increased hair volume but also developed pimples, likely due to the serum stimulating sebaceous glands.

      community 18M 10 months on anti-androgens and oral min

      in Progress Pictures  50 upvotes 2 years ago
      An 18-year-old male used anti-androgens and oral Minoxidil for 10 months to treat hair loss. He initially used 1mg Finasteride and 5% topical Minoxidil for 5 months, then switched to Dutasteride for 4.5 months and inconsistently used 5mg oral Minoxidil for 2 months due to availability issues.

      community [28yo] 5 months treatment. Oral fin , trop Minox and derma pen

      in Minoxidil  24 upvotes 2 weeks ago
      A 28-year-old user shared their positive experience with hair loss treatment using 1mg oral finasteride daily, topical minoxidil nightly, and weekly dermapen sessions. They reported increased confidence despite minor side effects like dandruff and gray hair.

      community Switching to minoxidil and tretinoin from just minoxidil

      in Minoxidil  6 upvotes 1 year ago
      The user is considering switching from a 5% minoxidil and 0.1% finasteride mix to a combination of 5% minoxidil, 0.1% finasteride, 0.01% tretinoin, and 1.5% azelaic acid due to low regrowth success. They are seeking advice on whether to use the new mix at night and continue the old mix in the morning or try oral minoxidil in the morning.

      community [21M] 3,5 Year Finasteride&Minoxidil Progress (Detailed & Pics)

      in Progress Pictures  64 upvotes 2 years ago
      A 21-year-old male shared his nearly 4-year experience with hair loss treatments, including finasteride, minoxidil, and other products, with initial success followed by shedding. He now continues with finasteride and oral minoxidil, noting changes in hair texture and slight hairline recession.

      community 2years progress (21 years old)

      in Progress Pictures  107 upvotes 1 year ago
      A user shared their two-year progress using 1mg finasteride, topical minoxidil, and occasional microneedling, noting no significant changes but a halt in hair loss progression. They recently started oral minoxidil and are considering a hair transplant.

      community Topical - Lantoprost .01%, MIN 10% DUT .05%, Hydrocortisone 1% Progrestron .025%

      in Treatment  6 upvotes 7 months ago
      A user was prescribed a topical treatment for hair loss including Latanoprost, Minoxidil, Dutasteride, Hydrocortisone, and Progesterone, after using an oral Minoxidil and Finasteride combo without significant results. Concerns were raised about the long-term use of hydrocortisone, with suggestions to consult a doctor regularly.

      community Question about clascoterone acne cream

      in Treatment  2 upvotes 4 days ago
      Clascoterone cream can be used on the scalp, but it may not be effective due to its dosage. AR antagonists like clascoterone are generally less effective than 5AR inhibitors for hair loss.

      community PG causing irritation when applying RU

      in Research/Science 2 years ago
      The user is experiencing irritation from using PG with RU58841 and is seeking alternative solutions like K&B in the UK. They report redness, itchiness, and flaky skin from the current treatment.
      Hairloss journey from 18 years of age

      community Hairloss journey from 18 years of age

      in Journals / Progress Pictures  236 upvotes 10 months ago
      The user began experiencing hair loss at 14 and is now starting treatment at 18 with a topical solution of 10% minoxidil-finasteride and ketoconazole shampoo. Oral finasteride was not recommended due to potential effects on growth, and microneedling will be considered after four months.

      community 1 years update [Finasteride, 5 mg oral minoxidil and recently topical minoxidil with 1.5 mm dermarolling]

      in Progress Pictures  107 upvotes 3 years ago
      Making a 1 year update on hair loss treatment of Finasteride, 5 mg oral minoxidil and topical minoxidil with 1.5 mm dermarolling; the user experienced some face pimples, baggy eyes, and had tried skin care. They also used fiber with their hair product and left it for a few days to make it look visually better. Replies were positive and one asked if using both oral and topical minoxidil was overkill.

      community 14 Months Dut/Minox/Microneedling + 13 Months HRT

      in Transgender  38 upvotes 2 weeks ago
      The user shared their hair regrowth journey using treatments like dutasteride, minoxidil, microneedling, tretinoin, Nizoral, silica, biotin, and hormone replacement therapy (HRT) with cyproterone and estradiol. They reported substantial hairline improvement and some crown thinning, with hopes for further progress.

      community February 2024 vs December 2024

      in Progress Pictures  19 upvotes 1 year ago
      A 22-year-old male used topical Minoxidil twice daily from March to July, then once daily from August to December, along with biotin tablets and occasional dermastamping. The biotin dosage was 5mg daily.