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GlossaryPregabalin

medication used to treat nerve pain and seizures

Pregabalin, also known by the brand name Lyrica, is a medication primarily used to treat nerve pain, epilepsy, and generalized anxiety disorder. It works by binding to certain calcium channels in the nervous system, which helps to reduce the release of neurotransmitters involved in pain and seizure activity.

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community After quitting min and fin I asked AI on how fix the mess I am in and it says:

in Technology 11 months ago

Prolonged use of topical minoxidil and finasteride can lead to neuroendocrine and autonomic dysfunction, causing severe sensitivity and side effects. Recovery involves avoiding these treatments, supporting neurosteroid recovery, calming the sympathetic system, and rebuilding scalp health naturally.

community pyrilutamide GB update please? Anything no matter how big or small

in Update 34 upvotes 4 years ago

The effects of Finasteride on hair loss and its side-effects, such as aching balls. The user has been taking it for two years with no changes to the symptom.

community Topical Valproic acid/sodium valproate — has anyone tried this?

in Question 2 upvotes 6 years ago

The conversation is about using valproic acid, an anti-seizure medication, as a topical treatment to promote hair growth. The original poster is seeking personal experiences from those who have tried this method.

community ABS-201 Trial - What should I know going in

in Research/Science 28 upvotes 3 months ago

The conversation is about a user preparing to join the ABS-201 clinical trial for hair loss treatment, which involves a prolactin inhibitor. The user plans to update others on their progress if enrolled.

community Pyrilutamide / KX-826 | Discussion EU

in Research/Science 4 upvotes 2 years ago

The conversation is about a user expressing concerns over the safety of a new drug called Pyrilutamide (also known as KX-826) for hair loss. The user will only trust the drug if it's permitted by EU regulations and sold by a reputable company.

community Setipiprant/PGE2 feedbacks?

in Question 4 upvotes 8 years ago

The conversation discusses using PGE2 as a hair growth stimulant, comparing it to minoxidil, and considering the addition of Setipiprant. Concerns about side effects like skin damage and cost are also mentioned.

community Upcoming Setipiprant clinical trials hint at systemic daily dosage

22 upvotes 10 years ago

The conversation discusses the safety, tolerability, and efficacy of oral Setipiprant tablets for treating androgenetic alopecia compared to finasteride. It mentions the high cost of Setipiprant on the black market and the trial's end date in September 2017.

community Pyrilutamide vs enzalutamide. Same thing?( Especially for biochemists, farmacologists)

in Research/Science 17 upvotes 3 years ago

Researching whether pyri and enza, which are stereoisomers of each other, share the same features related to CNS penetration/GABA Inhibition; safety and efficacy when used topically at 0.5-1%; and cost comparison between the two treatments.

community Allergan recruiting for Setipiprant trial in the US

13 upvotes 9 years ago

The conversation discusses a clinical trial for Setipiprant in the US, starting June 29th, with eligibility excluding recent users of minoxidil or finasteride. It encourages informed decision-making before signing up.

community Pyrilutamide/KX-826 for women?

in Treatment 1 upvotes 1 year ago

Pyrilutamide/KX-826 is being considered as a potential treatment for female androgenetic alopecia (AGA), but its high cost and limited data on effectiveness are concerns. Kintor markets it for both men and women.

community KX-826 (Pyrilutamide) on Amazon

in Treatment 9 upvotes 1 year ago

The conversation is about purchasing KX-826 (Pyrilutamide) on Amazon, now called Koshine. A user mentioned their order is expected to arrive between August 22 and September 13.

community EMA is re-examining Winlevi (clascoterone at lower concentration)

in Treatment 8 upvotes 11 months ago

Clascoterone in Winlevi, a topical AR antagonist, is being re-examined due to concerns about HPA axis suppression in adolescents, but it's unlikely to be banned for adult use in androgenetic alopecia (AGA). The European Medicines Agency recommended refusing Winlevi for acne vulgaris, but this may not affect Breezula's approval for AGA.

community So Pyrilutamide has been postponed by one year. How likely is that to happen to GT20029

in Treatment 27 upvotes 2 years ago

The conversation discusses the delay in the release of a new hair loss treatment, Pyrilutamide, and speculates on potential safety concerns as a reason for the delay. It also mentions GT20029 as another future treatment option, with a release at least five years away, and touches on the avoidance of research chemicals due to uncertainty about their authenticity.

community KX-826 Pyrilutamide1% coming soon

in Update 152 upvotes 1 year ago

KX-826 Pyrilutamide 1% is launching soon, and users are discussing its potential benefits and drawbacks compared to other treatments like Minoxidil and finasteride. Some users are skeptical about its effectiveness, while others are hopeful it will be a safer alternative.

community Bicalutamide vs Finasteride for female AGA plus TE

in Female 3 upvotes 4 months ago

OP is considering Bicalutamide for female AGA and TE but is concerned about its side effects and effectiveness compared to Finasteride. OP is also using Minoxidil and Spironolactone but is experiencing significant shedding and is unsure if it's androgen-driven or due to Minoxidil changes.

community Anyone here used spirolactone/cyproterone acetate/bicalutamide?

in Chat 4 upvotes 9 months ago

The conversation discusses the use of spironolactone, cyproterone acetate, and bicalutamide for hair loss, with concerns about side effects like gynecomastia and depression. Topical spironolactone is considered safe for men and effective when combined with regular treatments.

community started RU58841 today and am panicing

in Treatment 8 upvotes 2 years ago

A user started using RU58841 for hair loss and experienced anxiety and physical discomfort. Other users suggested avoiding the treatment due to similar side effects and recommended alternative treatments like pyri.

community Koshine 826 (Pyrilutamide). Any results after 5 months since it's been released?

in Product 12 upvotes 1 year ago

Koshine 826 (Pyrilutamide) has mixed reviews, with some users experiencing side effects like insomnia and others seeing minimal results. Concerns about the company's transparency and lack of progress photos are noted.

community Beeezula off label (winlevi compounded)

in Treatment 7 upvotes 4 years ago

User seeks availability of Breezula and its delayed trials. Asks for success with similar topical antiandrogens like fluridil.

community Pyrludimide (KX-826) or Breezula (clascoterone)

in Treatment 9 upvotes 3 months ago

The conversation is about hair loss treatments, specifically Pyrludimide (KX-826) and Breezula (clascoterone), with the user unable to tolerate finasteride and dutasteride. The user plans to use these treatments alongside minoxidil, considering the efficacy and availability of each option.

community Hair Loss Associated with Escitalopram (anti-depressant). Do SSRIs Affect the Hair Follicle?

in Research/Science 7 upvotes 2 years ago

A 22-year-old male experienced hair loss potentially linked to escitalopram, which stopped after switching to vortioxetine. His depressive symptoms improved with continued treatment.

community Setipiprant trial results

in Update 10 upvotes 7 years ago

Setipiprant trial for hair loss failed, showing no difference between placebo and treatment. Discussion also noted placebo users reporting side effects.

community I’m starting PTD-DBM and valproic acid today - anyone with experience?

in Treatment 2 upvotes 4 years ago

The conversation is about using PTD-DBM and valproic acid for hair loss. The user is inquiring about the dosage of these treatments, noting that valproic acid is used at a 7.5% solution.

community KX-826: My initial thoughts and observations on pyrilutamide...

in Treatment 1 upvotes 1 year ago

The user tried pyrilutamide for hair loss and noticed reduced scalp itch and improved skin but stopped due to mild heart sensations. They plan to update after consistent use, noting improved sleep when applied at night.

community Does anyone take bicalutamide for fphl? If so which dose

in Female 4 upvotes 3 years ago

The conversation is about a female seeking advice on using bicalutamide for female pattern hair loss (FPHL) and considering switching from pumpkin seed oil pills to a stronger treatment. She is looking for dosage information to discuss with her dermatologist.

community No side effects on pyrilutamide / KX-826 so far

in Research/Science 207 upvotes 4 years ago

User TopBack56 and friends tried pyrilutamide (KX-826) for hair loss without experiencing negative side effects. They observed fine vellus hairs but no thick hair growth yet, and plan to add GT20029 to their regime after safety trials.

community Is it Ritalin? (23 F)

in Question 6 upvotes 6 years ago

A user suspects Ritalin is causing hair loss due to vasoconstriction and is considering trying Ginkgo Biloba after already taking a multivitamin and hair supplement. Another user mentions experiencing hair shedding with Vyvanse and Dexedrine.

community 5mg KX 826 Worked. Will 2.5mg Hold?

in Technology 6 upvotes 1 year ago

Reducing the dose of Pyrilutamide from 5mg to 2.5mg may still maintain hair loss results, but effectiveness can vary. Users discuss the cost and dosage implications, with some cautioning against reducing the dose due to its dose-dependent nature.

community cb-03-01 research chem (winlevi/clascoterone cream)

in Technology 3 upvotes 2 years ago

The user is considering using CB or clascoterone for hair loss, potentially as an alternative to RU. They're also contemplating asking a dermatologist for topical clascoterone cream to apply to their temple.

community When will Breezula be released and how does it compare to KX-826?

in Research/Science 2 upvotes 10 months ago

Breezula (clascoterone) is expected to be available by late 2026, showing good long-term results with minimal side effects. KX-826 (pyrilutamide) acts faster but is still in earlier development stages.