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      community Pelage PP405 Phase 2a completed.

      in Research/Science  61 upvotes 4 months ago
      Minoxidil, finasteride, and RU58841 are discussed as treatments for hair loss, with excitement around a new drug, PP405, and a reformulated oral minoxidil in trials. Concerns about cost, side effects, and long-term use are also mentioned.

      community 4.5 months of Dut/5% topical min

      in Progress Pictures  39 upvotes 1 year ago
      OP saw significant hair growth after starting scalp exfoliation and using 5% topical minoxidil for 4.5 months, along with microneedling initially. Users discussed the benefits of exfoliation and inquired about experiences with finasteride and dutasteride.

      community 3.5 months on 7%Minoxdil - 0.1%Finasteride - .025%Tret (Topical)

      in Progress Pictures  347 upvotes 2 years ago
      The user noticed a significant improvement in hair loss after 3.5 months using a topical treatment of 7% Minoxidil, 0.1% Finasteride, and 0.025% Tretinoin, which was prescribed and shipped from a pharmacy in Indiana. Other users discussed alternative products with varying concentrations of Minoxidil and Finasteride.

      community How can you make your own PP405

      in Research/Science  2 upvotes 11 months ago
      People are discussing making their own PP405 for hair loss treatment using JLX069 and DMSO. There is skepticism about the safety and effectiveness of this homemade solution, with some users expressing concerns about potential risks.

      community Pyrilutamide for 16 weeks, with some progress

      in Progress Pictures  40 upvotes 3 years ago
      User gained hair with topical minoxidil and finasteride, then experienced shedding after starting pyrilutamide. After 12 weeks, new hairs grew and existing hairs thickened, hoping for more improvement in a year.

      community Should I start fin+min treatment? Norwood 2

      in Treatment  2 upvotes 3 years ago
      25-year-old male with Norwood 2 hair loss tried PRP injections without success. Dermatologists didn't recommend finasteride or minoxidil, but suggested PRP + Mesotherapy for 50% improvement.

      community Testicular pain/discomfort....how long will this last? (29/m)

      in Question  5 upvotes 9 years ago
      A user experienced testicular pain after taking finasteride for hair loss and considered lowering the dose to 0.25mg to manage side effects. They also considered adding minoxidil to their routine while seeking advice on whether to continue or stop finasteride.

      community Verteporfin to deminiaturize follicles

      in Research/Science  8 upvotes 3 years ago
      User discusses verteporfin for hair regrowth through "super microneedling" and preventing scarring. They mention a case of an old man regrowing hair after a head injury and suggest verteporfin could recreate this result.

      community 50% test increase after 18 months of taking DUT

      in Update  57 upvotes 1 year ago
      A user reported a 50% increase in testosterone after 18 months of taking dutasteride for hair loss. The conversation includes skepticism about the reliability of single testosterone tests and questions about estrogen levels.

      community Am I A Good Candidate for a Procedure?

      in Transplants 1 year ago
      The user is using a topical solution with finasteride, minoxidil, and other ingredients, along with a red light laser cap and dermapen, to address hair thinning. They are considering a hair transplant but are advised to try dutasteride and oral minoxidil for 12 to 18 months before deciding.
      30 M - Harline recovery - Fin or transplant?

      community 30 M - Harline recovery - Fin or transplant?

      in General  53 upvotes 7 months ago
      A 30-year-old male is considering finasteride or a hair transplant for hairline recovery after 3 months of using Minoxidil foam without seeing regrowth. Another user advises against a hair transplant, suggesting it's too early.

      community Follicum releases some data from previous phase 2a trial

      in Research/Science  14 upvotes 3 years ago
      Follicum discovered that their drug FOL-005 increased hair count by 12 hairs per cm2 in patients with less than 255 hairs per cm2 and is planning a phase 2b trial. They are currently fundraising for the trial, and the drug may also be effective for women.

      community Castor oil home brews and regimens?

      in Question  4 upvotes 7 years ago
      Using castor oil, coconut oil, rosemary, tea tree oil, peppermint oil, and other essential oils for hair loss prevention. Emu oil and derma rollers are also discussed, with caution advised for coconut oil's comedogenic properties and taking castor oil orally.

      community Kintor Pharmaceutical Announces AR-PROTAC (GT20029) Approved for Acne and Androgenic Alopecia Clinical Trials in China

      in Technology  13 upvotes 5 years ago
      The conversation discusses the approval of Kintor Pharmaceutical's AR-PROTAC (GT20029) for clinical trials in China for acne and androgenic alopecia. One user expresses optimism about new treatments being developed and seeks clarification on how the new drug works, specifically if it temporarily degrades the AR protein to reduce DHT sensitivity in hair follicles.

      community There is news from pyrilutamide?

      in Product  32 upvotes 2 years ago
      The discussion is about a hair loss drug called pyrilutamide. Users discuss its efficacy, safety, and expected market release around 2025-2026, with some expressing concerns about the authenticity of current market offerings.

      community Do these two supplements inhibit 5alpha-reductase?

      in Chat  1 upvotes 5 years ago
      Pumpkin Seed Oil and Perilla Oil (with alpha-lipoic acid, linoleic acid, and oleic acid) are discussed as potential 5alpha-reductase inhibitors. The conversation focuses on their effectiveness for hair loss treatment.

      community 34/F with hair thinning

       6 upvotes 7 years ago
      A 34-year-old female is experiencing hair thinning after stopping birth control pills and a damaging hair treatment. She has normal bloodwork and a normal trichogram but is considering trying MSM or Saw Palmetto for her hair loss.

      community Bloodwork after 8 months on finasteride, is this normal?

      in Update  27 upvotes 2 years ago
      A user on finasteride for 8 months shared bloodwork results showing increased testosterone and estradiol levels, with concerns about high LH. Responses advised monitoring for symptoms but noted levels are within reference ranges.

      community Castor Oil - Yay or Nay?

      in Product  9 upvotes 5 years ago
      The conversation discusses the potential benefits of castor oil for hair thickening, with one user noting it may increase prostaglandin E2 and decrease PGD2. The original poster plans to take 1-2ml orally daily.