A Phase 1 update for the HMI 115 clinical trial, which involves 16 participants and is expected to end in July 2023; as well as changes to the recruitment process, including treatment protocols with Minoxidil, Finasteride, and RU58841.
A user is seeking a prescription for topical finasteride with minoxidil from their general practitioner, preferring it over buying online. They are advised that a dermatologist might be needed for the prescription, and alternatives like CVS clinics or online services are suggested.
A user is starting a hair loss treatment with a 3-in-1 spray containing finasteride, minoxidil, and tretinoin. They are concerned about whether to continue shaving their head and how to determine if hairfollicles are dead.
User is using topical Minoxidil (100 mg/day) and Finasteride (1 mg/day) but experiencing hair growth everywhere except the top of the scalp. They seek advice on improving scalp hair regrowth.
Hair loss is influenced by scalp tension, stress, and environmental factors, not just hormones. Treatments like tretinoin, microneedling, scalp massage, and Botox can reduce tension and improve hair health.
Topical treatments like minoxidil and finasteride are preferred for hair loss due to ease of use and natural appearance. Hair systems are considered high-maintenance and less genuine.
A 31-year-old man plans to address his receding hairline using topical finasteride, followed by topical minoxidil 5% with microneedling, and ketoconazole shampoo. He seeks advice on product availability in India.
The user experienced positive hair regrowth using a routine of microneedling every 3 days, applying a blend of castor oil with peppermint and rosemary, bhringraj oil, and moringa oil, and using Pura D'Or DHT-blocking shampoo. They also take multivitamins and saw palmetto daily, reporting no side effects from saw palmetto.
The conversation discusses using topical finasteride and minoxidil for hair loss, focusing on the crown and mid-scalp areas. The user is optimistic about seeing results in 3 to 6 months.
Minoxidil is causing hair growth in unexpected areas like the forehead, eyebrows, and body, rather than the scalp. Users discuss the effects of both topical and oral minoxidil, with some also using finasteride and experiencing varied results.
A 19-year-old noticed hair thinning and mild receding hairline, opting for a treatment regime excluding finasteride and minoxidil. The regime includes derma rolling, rosemary and coconut oil, a massage comb, a DHT-blocker shampoo, and vitamins B12 and Biotin.
A user's 18-month hairline progress using minoxidil, finasteride, Nizoral, microneedling, and scalp massage. They share their routine and discuss treatment effectiveness and photo order confusion.
A 27-year-old male is using a regimen of topical finasteride, minoxidil, ketoconazole, and biotin for hair loss, and has recently started oral finasteride despite previous side effects. He is considering shaving his head and is advised that a hair transplant might be possible once hair loss stabilizes.
The user is concerned about having a straight, low hairline after a hair transplant and is unable to take finasteride due to high estrogen and prolactin levels. They have used minoxidil with limited success and are considering further transplants to lower the hairline, while others suggest the risks of using up donor hair too quickly.
The conversation is about a 24-year-old using microneedling and essential oils, specifically neo hair lotion, to promote hair growth on the temples. The user reports seeing hair growth without using medications, using a 0.5 mm needle roller and planning to switch to a 1.0 mm needle.
The user regained hair using a routine including Nizoral shampoo, 0.5mg finasteride daily, topical minoxidil at night, and microneedling every two weeks. They switched from topical to oral finasteride to save money.
Beard hair grown with minoxidil can become permanent because it is not sensitive to DHT, unlike scalp hair, which requires ongoing minoxidil use even with DHT blockers like finasteride or dutasteride. Dutasteride reduces scalp DHT significantly but not completely, which may explain why scalp hair still needs minoxidil for maintenance.
A 19-year-old experiencing early hair loss started using finasteride to address diffuse thinning, despite concerns about potential side effects. They also use T/Gel and OGX Thick and Full shampoo, and have a dermatologist appointment scheduled to explore possible allergies.
The conversation discusses hair loss treatments, focusing on reducing scalp itching and dandruff using natural shampoos, witch hazel, and apple cider vinegar. The user also mentions using finasteride and observing potential regrowth, though it's difficult to confirm.
The user is using multiple topical treatments including Minoxidil, RU58841, and Spironolactone, along with supplements, to address hair loss and is considering starting oral Minoxidil. They plan to begin oral finasteride soon after experiencing side effects from topical dutasteride.
Scalp tension from the occipitalis muscle is theorized to contribute to hair loss, but most believe DHT and genetics are the main causes. Treatments like finasteride and minoxidil are considered more effective than addressing scalp tension.
A 28-year-old male started balding at 20 and has been using Bosley Shampoo, minoxidil, finasteride, microneedling, and exosomes/PRP treatments. He also underwent scalp micropigmentation to hide thinning hair and is seeking feedback on regrowth progress.
The conversation discusses hair regrowth using finasteride, minoxidil, Nizoral, and oral Saw Palmetto. Users share mixed opinions on the effectiveness of these treatments, with some suggesting additional treatments like dutasteride.
Why the top of the head is affected by hair loss more than other areas, and treatments such as surgery, medications like minoxidil, finasteride, and RU58841 to treat it.
A user shared progress on hairline improvement after 3 months using oral finasteride, topical minoxidil, and a dermaroller. They also use Alpecin Caffeine shampoo daily and ketoconazole shampoo weekly.
IGFBP‐rP1 shows potential for treating androgenic alopecia by influencing hair cycle transitions. Increasing IGF-1 levels may have similar effects to Minoxidil and 5-AR inhibitors in reducing hair loss.
Pelage Pharmaceuticals' PP405 aims to treat hair loss by reactivating dormant hairfollicle stem cells, showing promising results in early trials. The company plans to present their findings at the American Academy of Dermatology Annual Meeting in 2026.
A 27-year-old is using finasteride, minoxidil, microneedling, and Pilexil shampoo to combat hair loss, with plans to add Nizoral shampoo and light stimulation. Initial results show reduced hair loss and some hair thickening, despite a period of shedding.