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      community CTE and lots of shedding for over a year

      in Female  5 upvotes 2 years ago
      A female user has experienced severe hair shedding since stopping birth control in late 2022, diagnosed as telogen effluvium with no signs of androgenetic alopecia. Despite healthy living and optimal bloodwork, she continues to shed hair daily but also sees significant regrowth.

      community Realistic Dutasteride Progress for NW7

      in Progress Pictures  67 upvotes 1 year ago
      The user shared their hair loss treatment progress using oral and topical dutasteride, topical minoxidil, microneedling, and keto shampoo. They plan to possibly add LLLT, PRP with exosomes, and other treatments in the future.

      community Topical Dutasteride Progress (2.5 months)

      in Is this regrowth?  3 upvotes 1 year ago
      A 21-year-old male is using a topical treatment for hair loss, including Dutasteride, Minoxidil, Tretinoin, Ketoconazole, and Hydrocortisone, along with derma rolling. He reports no side effects from the treatment and seeks feedback on its effectiveness for hair regrowth.

      community HT scheduled. Am I over reacting?

      in Transplants  13 upvotes 1 year ago
      The user has scheduled a hair transplant after stabilizing hair loss with finasteride and minoxidil, considering additional dermarolling. They are advised to use 2500-3000 grafts conservatively for temple filling without lowering the hairline too much.

      community I wrote a poem about pp405 (potential treatment)

      in Satire  19 upvotes 1 year ago
      A poem humorously suggests hope for a new hair loss treatment, PP405, while users debate the effectiveness and side effects of current treatments like Finasteride. Concerns are raised about Finasteride's side effects, especially for young users, and skepticism about new treatments is expressed.

      community Dutasteride 2.5 mg Progress (6 months)

      in Progress Pictures  162 upvotes 2 months ago
      A 49-year-old male switched from Finasteride to Dutasteride 2.5 mg daily, along with oral Minoxidil 5 mg, resulting in significant hair regrowth and stopping hair loss after six months. Despite initial side effects like adrenaline spikes and urinary issues, the user is satisfied with the results and plans to continue the treatment.

      community Ginsenoside enriched formulation

      in Treatment 1 year ago
      Panax ginseng, specifically a ginsenoside-enriched formulation, is suggested as a potential hair growth treatment alongside finasteride and minoxidil. The user is considering trying panax ginseng despite limited availability and evidence.

      community HMI-115 update: Chime Biologics and Hope Medicine Enter Manufacturing Agreement to Speed up the Launch of First-in-class Antibody Drug HMI-115 Targeting Endometriosis and Androgenic Alopecia

      in Research/Science  110 upvotes 2 years ago
      Chime Biologics and Hope Medicine are speeding up the launch of a first-in-class antibody drug, HMI-115, for endometriosis and androgenic alopecia. The treatment involves a series of subcutaneous injections, has shown promising results in phase 1, and continues to promote hair regrowth even after the treatment is stopped.

      community Any chemists want to manufacture PP405 / JXL069? (Steps inside)

      in Research/Science  114 upvotes 1 year ago
      The conversation discusses the potential of PP405 as a hair loss treatment, with some users expressing skepticism and others hopeful about its development. There is also mention of other treatments like Minoxidil, Finasteride, and Pyrilutamide, with users debating the effectiveness and safety of self-experimentation versus waiting for clinical trial results.

      community Sooo whens the next big thing gonna come?

      in Chat  20 upvotes 2 months ago
      New hair loss treatments like VDPHL01, PP405, Gt20029, and Breezula are anticipated, with VDPHL01 possibly releasing in 2027/28. Current treatments include finasteride, dutasteride, and minoxidil, but new options are eagerly awaited.

      community Can we get a reality check on PP405?

      in Research/Science  81 upvotes 8 months ago
      PP405 is a promising hair loss treatment that may outperform minoxidil and finasteride by reviving dormant follicles and promoting significant regrowth. Results from ongoing trials are awaited, with a potential market release between 2028-2030.

      community Progress with low-dose topicals

      in Research/Science  4 upvotes 2 months ago
      The conversation discusses using low-dose topical finasteride, specifically 0.005% and 0.01%, for hair regrowth, with some users considering increasing the concentration for better results. Users share experiences with different dosages and combinations, including minoxidil, and discuss the effectiveness and availability of these treatments.

      community Finasteride FTM experiences after being on T for 2+ years?

      in Transgender  6 upvotes 2 years ago
      People are discussing experiences with finasteride for hair loss after being on testosterone for over two years. Users report varying results, with some experiencing regrowth and no side effects, while others emphasize the importance of starting treatment early to prevent further hair loss.

      community Mechanism of action of alfatradiol (17 alpha estradiol)

      in Research/Science  5 upvotes 2 years ago
      The conversation discusses the mechanism of action of alfatradiol (17 alpha estradiol) in treating hair loss. It explores theories that it either inhibits 5 alpha reductase to prevent T->DHT conversion or aromatizes scalp T into 17-alpha-estradiol to save hair.

      community Progress- 3 months, 5% Minoxidil, 0.1% Finasteride

      in Is this regrowth?  232 upvotes 1 year ago
      The user experienced significant hair loss after stopping a treatment of 5% Minoxidil and 0.1% Finasteride, which they had used from December 2021 to January 2024. They resumed the treatment in April 2025, hoping for regrowth, and are considering additional treatments like transplants and steroid injections.

      community HT booked, taking finasteride and losing ground?

      in I'm Starting Treatment  1 upvotes 4 months ago
      The user is concerned about hair loss despite taking finasteride and has a hair transplant scheduled. They experience scalp itching and burning, which hasn't been relieved by various treatments, and another user suggests using ghk-cu & ahk-cu serum and Koshine kx-826/pyrilutamide for relief.

      community My summation of PP405 - looks promising

      in Research/Science  206 upvotes 1 year ago
      PP405 shows promise for hair regrowth by manipulating stem cell characteristics and lactate dehydrogenase, with Phase 2a trials pending. Google Ventures' $15M investment suggests confidence, but results and market availability remain uncertain.

      community DHT Gel (2.5%) to beard area + Dut + Pyri 1% + Minox

      in Research/Science  5 upvotes 9 months ago
      The conversation discusses using a combination of DHT gel, dutasteride, pyrilutamide, and minoxidil to promote beard growth while minimizing hair loss. Users suggest consulting a doctor and considering genetic factors before proceeding.

      community Any treatment not nuking systemic DHT levels?

      in Finasteride/Dutasteride  16 upvotes 4 months ago
      Hair loss treatments that avoid significantly lowering systemic DHT levels, focusing on topical options like dutasteride mesotherapy, minoxidil, and ketoconazole. The user is exploring alternatives like KX-826 and RU58841 due to concerns about hormone levels.

      community Topical Finasteride Gel 1% after 4 months — problems

      in Finasteride  156 upvotes 8 months ago
      The user experienced hair thinning due to a testosterone spike and used a minoxidil solution and topical finasteride gel. After four months, the gel caused side effects without improving hair thinning, leading to questions about continuing or adjusting the treatment.

      community Lets do this!!! My current Stack

      in Treatment  4 upvotes 1 year ago
      The conversation discusses a hair loss treatment regimen using Alfatradiol, Pyrilutamide, and Minoxidil. The user shares their current stack of these treatments.

      community anything to add to my regime?

      in Advice 6 years ago
      The conversation is about a hair loss treatment regimen that includes finasteride, dutasteride, oral minoxidil, Dermapen, quercetin, N-acetyl L-cysteine, biotin, millet seed extract, MSM, OPC, green tea extract, high-dose vitamins B1-B12, boron, and silica. The user is seeking advice on additional treatments.

      community Clascoterone 12 months phase 3 result out

      in Treatment  45 upvotes 2 months ago
      Clascoterone is promising for hair loss, showing 24.5% improvement in satisfaction compared to placebo. Users consider it an alternative to finasteride, with concerns about absorption and side effects.

      community 6 months on minoxidil and finastreride

      in Progress Pictures  1660 upvotes 5 months ago
      A 24-year-old experienced improved hair growth using 5% minoxidil, 1 mg finasteride, and dermastamping, but faced side effects like low libido and mild erectile dysfunction. They plan to reduce finasteride dosage after full results and may consider a hair transplant if thinning recurs.