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990-1000 / 1000+ resultscommunity Aromatase Upregulation along with DHT down regulation could possibly hold the cure
The post discusses the potential of upregulating aromatase to treat hair loss, suggesting that increasing CCL2 levels through Vitamin D or microneedling might help. The user questions why microneedling doesn't work for everyone, especially those with advanced hair loss.
community What is next for pp405 in phase 2b?
PP405 is progressing to Phase 2b trials, with results expected in late 2025 or early 2026, and potential Phase 3 trials in 2026. Some users experienced side effects from finasteride and are hopeful for PP405 as an alternative treatment.
community Anagenic Pyrilutamid, has anyone tried this?
The conversation is about personal experiences with Anagenic Pyrilutamid for hair loss and what carriers people use with it. No specific treatments or outcomes are mentioned.
community Guys, we finally have an alternative to finasteride
A combination of pyrilutamide, minoxidil, and alfatradiol is proposed as an effective alternative to finasteride for treating mild to moderate hair loss, claiming to stabilize hair loss and improve thickness without finasteride's side effects. Some users are skeptical about the effectiveness and approval of these treatments, while others are interested in trying them due to finasteride's side effects.
community Topical application of Apple Skin 15% Procyanidin B2 extract makes hair noticeably thicker
Hair loss discussion includes homemade 15% Procyanidin B2 apple skin extract as alternative to Minoxidil. User reports thicker hair, but no new growth yet.
community Pyrilutamide users, any updates?
Treatment for hair loss, including Pyrilutamide, Minoxidil, Finasteride, and RU58841; with some users reporting success in growing vellus hairs.
community Is something finally happening here? What do you think?
The conversation discusses hair regrowth using RU58841 and Minoxidil in the morning, and Minoxidil with needle massage in the evening. The user is inquiring if there are signs of hair regrowth by comparing photos from September 3 to recent ones.
community PP405 Update and My Take on Pelage
Pelage Pharmaceuticals raised $120M for their hair loss treatment, PP405, showing strong investor confidence despite limited data. There is skepticism about its efficacy and long-term effects compared to treatments like GT20029.
community 11+ months on Minoxidil and finasteride is it balding or regrowth?
The user has been using minoxidil and finasteride for almost a year, experiencing initial shedding, followed by regrowth, and then another shedding phase. They are concerned about the effectiveness of their current regimen and are considering adjusting their finasteride dosage.