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      PP405 Identity Research

      community PP405 Identity Research

      in Research  292 upvotes 10 months ago
      PP405 is a potential hair loss treatment that inhibits mitochondrial pyruvate carriers, increasing lactate dehydrogenase activity and stimulating hair follicle stem cells. In a phase 1 trial, 31% of participants showed over 20% hair density increase with PP405 treatment.

      community A little perspective from Bill Burr

       6 upvotes 12 years ago
      The user has been using Propecia for about 11 months and believes it has slowed hair loss. They acknowledge likely future hair loss and emphasize the value of a positive attitude.

      community Don't use PP405 from everychem. it is likely fake.

      in Research/Science  66 upvotes 11 months ago
      PP405 from Everychem is likely fake and potentially harmful, with concerns about its stability and the risk of using the wrong MPC inhibitor, which could damage hair follicles. The real PP405 was studied under strict conditions, and DIY attempts are discouraged due to unknown formulation and quality control.

      community No side effects on pyrilutamide / KX-826 so far

      in Research/Science  207 upvotes 4 years ago
      User TopBack56 and friends tried pyrilutamide (KX-826) for hair loss without experiencing negative side effects. They observed fine vellus hairs but no thick hair growth yet, and plan to add GT20029 to their regime after safety trials.

      community Pyrilutamide: hairloss continues

      in Treatment  12 upvotes 3 years ago
      The conversation is about someone experiencing continued hair loss despite using Pyrilutamide and considering the need for more time or better quality control for the treatment. Another person suggests waiting for the drug to be officially approved due to potential quality issues with current products.

      community Hormone tests to decide on oral fin

      in Finasteride/Dutasteride  4 upvotes 1 year ago
      The conversation discusses starting low-dose oral finasteride for hair loss, considering hormone levels and potential side effects like gynecomastia. Suggestions include using DIM for estradiol, vitamin B6 for prolactin, and lifestyle changes to optimize hormone profiles before starting treatment.

      community I’m afraid if using oral finasteride + topical minoxidil (28 yo)

      in General  77 upvotes 9 months ago
      A user is concerned about the long-term commitment and potential side effects of using oral finasteride and topical minoxidil for hair loss. They are debating whether to accept their hair loss or start the treatment despite mixed results from others.

      community Zix + Topical Fin : Blood Test Before/After, AMA and suggestions

      in Treatment  49 upvotes 5 years ago
      A user's plan to use Zix and topical finasteride (5AR inhibitors) for hair loss, followed by blood testing before/after. The user has suggested creating a fund to cover part of the cost of their blood tests. Replies to their post discuss the effectiveness of the treatments.

      community 1 year of .5mg oral dut, .3% topical fin and 6% topical min everyday

      in Finasteride/Dutasteride  88 upvotes 9 months ago
      A 25-year-old is experiencing hair thinning despite using 0.5mg oral dutasteride, 0.3% topical finasteride, and 6% topical minoxidil daily for a year. They are considering increasing dutasteride dosage and exploring other treatments like microneedling and KX 826, while seeking further medical opinions on their condition.

      community First week finished on finasteride 0.5mg MWF

      in Finasteride/Dutasteride  9 upvotes 1 year ago
      The conversation discusses starting finasteride for hair loss, with the original poster noting reduced scalp itching and oiliness after the first week. Users share experiences with different dosages and schedules, concerns about side effects, and the potential impact on prostate cancer detection.

      community Had sides on finasteride ? A word of hope.

      in Finasteride  26 upvotes 8 years ago
      A user's experience with hair loss treatments, including finasteride and other options such as RU58841, Nizoral, Pumpkin Seed, and Adenosine; the importance of being in a positive frame of mind when considering taking finasteride; and the need to address life issues before starting finasteride.

      community The use of peptides to enhance hair growth from wounding

       5 upvotes 9 years ago
      The conversation discusses using peptides BPC-157 and TB-500, combined with microneedling, to potentially enhance hair regrowth. The user plans to try BPC-157 due to its lower cost and reports of hair growth, despite limited human trials and concerns about side effects from other treatments like minoxidil and finasteride.

      community day 107 of kx826 .5% . 1+ years on topical minoxidil.

      in Progress Pictures  18 upvotes 1 year ago
      The user has been using topical minoxidil for over a year and added kx826/pyrilutamide to improve hair growth, avoiding finasteride due to side effects like lowered libido and panic attacks. They report positive results with reduced shedding and healthier hair, particularly in areas previously unresponsive to minoxidil.

      community 1 Year on fin/dut + ketoconazole shampoo

      in Progress Pictures  1 upvotes 7 months ago
      The user has been using dutasteride, finasteride, and ketoconazole shampoo for hair loss, recently adding minoxidil and tretinoin, and plans to start microneedling. They advise starting treatments early to maintain hair, as regrowth is more challenging.

      community My current nuclear stack. Thoughts?

      in Chat  7 upvotes 2 years ago
      The user is using RU58841 twice daily, dutasteride 0.5mg every two days, dutasteride mesotherapy every three months, and 20mg oral minoxidil daily. Other users suggest this regimen is excessive and recommend adding microneedling and ketoconazole shampoo.

      community Good hair days; finastride

      in Finasteride/Dutasteride  14 upvotes 5 years ago
      The user expresses positivity about managing hair loss and celebrates good hair days. They mention using finasteride (Propecia) as part of their treatment.

      community CB-03-01 users come forward!

       13 upvotes 6 years ago
      The conversation discusses the potential of a new hair loss drug, CB-03-01, with users sharing their experiences and seeking advice on dosages and application methods. One user mentions using topical finasteride, minoxidil, dermarolling, and a clean diet for hair maintenance but is interested in CB-03-01 due to side effects from finasteride.

      community Using 1% Clascoterone cream on hairline?

      in Chat  4 upvotes 2 months ago
      A 30-year-old man with hairline recession is considering using 1% Clascoterone cream on his hairline while awaiting a 5% Breezula product. He has been using oral Minoxidil for four years but stopped using Finasteride due to side effects.