community Switch to Dut??
Considering a switch from finasteride to dutasteride for hair loss treatment, and the use of minoxidil as a last resort due to its effects on hair texture.
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930-960 / 1000+ resultscommunity Finasteride results after 2 years
A 36-year-old male has been using 1 mg finasteride for 2 years and recently switched to dutasteride for 3.5 months, noticing stable hair with slight thickening and no significant side effects. Other users discuss their experiences with finasteride, minoxidil, and dutasteride, with some reporting no results or side effects.
community Does DHT give you a leaner face?
Finasteride and dutasteride may increase estrogen levels, leading to water retention and a fuller face. Users discuss managing these effects with lifestyle changes and supplements like zinc and DIM.
community Anyone used CB-03-01 (clascoterone), is it worth it, too risky??
The user experienced side effects from low-dose topical finasteride and is considering using clascoterone (CB-03-01) despite concerns about its risks and cost. They seek advice on its effectiveness and potential side effects compared to other treatments like alfatradiol and fluridil.
community Dutasteride Mesotherapy or Oral Finasteride
A user is considering dutasteride mesotherapy versus oral finasteride for hair loss, with concerns about side effects. Other users share experiences with both treatments, suggesting oral finasteride as more effective and cost-efficient, while also discussing the use of minoxidil, alfatradiol, and potential side effects like gynecomastia.
community Are we still getting the PP405 phase 2a results by the end of March?
People are discussing the anticipated release of PP405 phase 2a results, expected by the end of March, with some skepticism about its effectiveness. There is cautious optimism due to past experiences with similar treatments like Breezula, despite concerns about the lack of presentation at the AAD 2026 conference.
community Finasteride Worries
community important questions about RU58841
The user has been using finasteride for hair loss and is considering adding RU58841. They ask about RU58841's effectiveness, potential heart side effects, duration of action, dosage increase over time, transitioning to GT20029, and where to find the liquid form.
community Stemoxydine used for shortening the ugly duckling phase after HT?
The conversation is about whether stemoxydine can shorten the dormant phase after a hair transplant, known as the ugly duckling phase. There is skepticism about whether it actually works as claimed.
community Is there any role for topical DHT antagonists, or does a 5-AR inhibitor remove the need for them as therapy
Topical androgen receptor antagonists may not be necessary if 5-AR inhibitors like finasteride or dutasteride effectively reduce DHT levels. Combining a 5-AR inhibitor with a topical androgen antagonist could potentially enhance treatment, but oral use of androgen antagonists is too risky due to severe side effects.
community 5 months progress 5 mg oral min + dut after a year of finasteride with no effect.
The user experienced hair regrowth after 5 months on 5 mg oral minoxidil and 1 mg dutasteride, following a year of ineffective finasteride use. They noticed progress after an initial shedding phase and hope for further improvement, with expectations of near-max regrowth around 18 months.
community How to Dilute Topical Finasteride?
A user wants to dilute topical finasteride due to side effects like dizziness and is seeking advice on how to do it, preferably without mixing with minoxidil. They are unable to find specific guidance online and are looking for help from the community.
community 4.5-month progress; dut 3x/week + topical min 1-2x daily + microneedling 2x/month
Hair loss progress in 4.5 months using dutasteride 3x/week, topical minoxidil 1-2x daily, and microneedling 2x/month. Users praised the significant improvement.
community The dose dependent nature of the cardiac effects RU58841
Reducing the dose of RU58841 from 25mg to 7.5mg topically helped minimize heart palpitations. Users discussed the cardiac effects of RU58841 and minoxidil, noting that no treatment is completely free of side effects.
community 2 years on fin only :) EOD. No sides.
A user shared their 2-year progress using finasteride every other day with no side effects. Others discussed their experiences, shedding cycles, and patience with the treatment.
community Anyone use a custom topical from Skin Medicinals with latanoprost ?
The conversation discusses using a custom topical from Skin Medicinals containing latanoprost for hair loss, which helps move hairs into the anagen phase. The user is curious about the cost and effectiveness of this treatment.
community Alright, so what’s the best way to lower scalp DHT with the least impact on serum DHT?
Topical finasteride affects serum DHT less than oral forms, while dutasteride mesotherapy may impact only the scalp with minimal serum DHT effects. Oral dutasteride once a week is suggested to have few side effects.
community PRP Experience/Result Discussion
community Does dutasteride brand matters ?
community My personal thoughts on DHT. belive it or not
The conversation discusses a personal theory on the role of DHT in stress and reproduction, suggesting it converts testosterone for reproductive traits. The discussion includes skepticism and mentions individual differences in physiology and neurochemistry.
community Already on topical min and topical fin, considering adding stemoxydine 5% to treatment regimen
The user is using topical minoxidil and finasteride with good results and is considering adding stemoxydine 5% to their regimen. Another user suggests trying it if financially feasible, as results can vary.
community Fluridil downregulates androgen receptor expression?
Fluridil may decrease the number of androgen receptors in hair follicles by up to 95%. This suggests a different action mechanism from other non-steroidal antiandrogens like RU58841, indicating they might be used together.
community Seeking advice from dut non-responders who used RU
The conversation discusses hair loss treatments, specifically the use of RU58841 by individuals who did not respond to dutasteride. Users share experiences with maintaining hair using RU58841 and mention trying pyrilutamide and the upcoming availability of pp405.
community Are 10% fluridil formulations effective?
The user is asking if using a 10% fluridil formulation would be effective for blocking scalp androgens in addition to their current treatment of oral dutasteride.
community Anyone having success with pyrilutamide?
community Fluridil solution at Actifolic
Fluridil, also known as Topilutamide or Eucapil, is discussed as a treatment for hair loss. It is noted as an androgen receptor antagonist, not a vasodilator.
community Visible results after 10 weeks, (M25), E-En+DHPA, bica, min
Visible hair improvement after 10 weeks using minoxidil, estradiol enanthate, acetophenide algestone, and bicalutamide. The user is a 25-year-old male with reduced testosterone levels, expressing a preference for less masculinity.
community P5P supplementation for fin sides.
P5P supplementation helped reverse finasteride side effects, particularly by lowering prolactin levels and restoring sensitivity. The user experienced significant improvement within a day and full recovery in a few days.
community Did Dutasteride solved the ED you had with Finasteride?
Some users experienced erectile dysfunction with finasteride but not with dutasteride, while others had issues with both. Individual reactions vary, with some reporting improved mood and hair growth on dutasteride.
community 2 months Fin/min update. 1mg fin a day, 5%min-0.1%fin topical twice a day, Vitamin D3 50,000 IU once a week.
A user shared their 2-month progress using 1mg finasteride daily, 5% minoxidil with 0.1% finasteride topically twice a day, and Vitamin D3 weekly. They experienced initial side effects like weaker erections and mood swings, which resolved after one month.