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      community How good are anti-androgens? Are they worth seeking?

      in Research/Science 1 month ago
      The conversation discusses hair loss treatments, including dutasteride, oral minoxidil, finasteride, and potential additions like topical finasteride, minoxidil, micro-needling, and topical anti-androgens such as RU58841. The effectiveness and worth of these treatments, including localized dutasteride mesotherapy, are considered.

      community Thoughts on the future of pp405?

      in Research/Science  43 upvotes 6 months ago
      PP405 is considered a promising hair loss treatment, potentially replacing minoxidil but not finasteride. Users are hopeful for future treatments like GT20029 and VDPHL01, while remaining cautious about effectiveness and side effects.

      community Doubtful of RU58441's negative effects

      in Research/Science  2 upvotes 9 months ago
      RU58841's potential side effects, particularly heart palpitations, are debated, with some attributing them to contamination with minoxidil. Users report mixed experiences, with some seeing no side effects and others cautioning about the lack of reliable data on RU58841's safety.

      community 2.5 months of topical Finasteride

      in Progress Pictures  272 upvotes 5 months ago
      A user reported significant hair regrowth using a homemade 0.01% topical finasteride solution, highlighting its effectiveness and lack of side effects. The discussion included concerns about oral finasteride's side effects and the benefits of topical solutions.

      community Found a slide summary for PP405

      in Research/Science  37 upvotes 1 month ago
      PP405 shows promise in stimulating new terminal hair growth by activating dormant follicles, with no systemic adverse effects observed in a short-term trial. However, long-term efficacy remains unproven, and further trials are needed to confirm its potential as a hair loss treatment.

      community Serenoa repens (Saw palmetto)

      in Chat  1 upvotes 2 months ago
      Saw palmetto, a 5-alpha reductase inhibitor, caused unexpected side effects like breast changes and altered semen consistency, which resolved after stopping its use. Concerns about similar side effects with finasteride or dutasteride were expressed, and another user reported low libido and depression from saw palmetto.

      community Finasteride influence on other hormones

      in Finasteride/Dutasteride  8 upvotes 5 years ago
      Finasteride can affect hormone levels, potentially causing symptoms like puffy nipples and testicular pain, and may result in elevated prolactin and high testosterone. The user is seeking interpretation of these changes after taking finasteride.

      community 0.25 % fin and 0.25% dut together topically

      in Treatment  3 upvotes 4 months ago
      The user is dissatisfied with the results of using 0.3% finasteride and 6% minoxidil for hair thinning and is considering a topical treatment combining finasteride, dutasteride, minoxidil, melatonin, caffeine, and latanoprost. Another user suggests that high topical concentrations can lead to systemic exposure and recommends using oral dutasteride and microdosing topical finasteride.

      community Finasteride beats Dutasteride!?

      in Finasteride/Dutasteride  4 upvotes 1 month ago
      The user experienced side effects from switching to Dutasteride and is considering whether to lower the Dutasteride dose or return to daily Finasteride. They are uncertain about the best approach due to mixed results from different studies.

      community from fin to dut; from oral to topical minoxidil

      in Is this regrowth?  118 upvotes 1 year ago
      The user switched from finasteride to dutasteride and from oral to topical minoxidil, noticing better hair regrowth with the new regimen. They experienced no side effects from dutasteride and found topical minoxidil more effective than oral.

      community Finasteride affects both 5a reductase and 5b reductase

       7 upvotes 6 years ago
      Finasteride not only inactivates the 5a reductase enzyme but also affects the 5b reductase enzyme in a dose-dependent manner, which can impact sexual behavior and brain activity. The user experienced significant hair regrowth and side effects on 1mg of finasteride, which diminished after reducing the dose to 0.5mg, leading to no side effects and further hair improvement.

      community When you use 1 mg fin vs you use 2.5 mg dut

      in Satire  2265 upvotes 2 weeks ago
      Switching from finasteride to dutasteride can lead to varied results, with some experiencing better hair regrowth and fewer side effects, while others continue to lose hair. Dutasteride is generally seen as more effective but has a longer half-life, potentially extending side effects.

      community Has anyone tried this Ru58841 from Amazon ?

      in Product  3 upvotes 8 months ago
      RU58841 from Amazon is unreliable, with users reporting no benefits and side effects like eye swelling and chest pain. Rudirect is recommended for purchasing in Europe.

      community RU58841 in germany eventually facing legal charges

      in Hair Systems  32 upvotes 10 months ago
      The conversation discusses the use of RU58841 for hair loss, with concerns about its legality in Germany and potential legal consequences. Alternatives like finasteride and dutasteride are mentioned, with some users questioning the effectiveness and safety of RU58841.

      community I wish pp405 work and i have full head of hair in 2028-2030

      in Chat  106 upvotes 6 months ago
      People are hopeful about future hair loss treatments like PP405, GT20029, and VDPHL01, while some are currently using finasteride and minoxidil. There is skepticism about the effectiveness of new treatments, and some advise against hair transplants until more promising drugs are available.

      community hight pre-finasteride estrogen levels

      in Finasteride/Dutasteride  1 upvotes 2 years ago
      A user with high pre-finasteride estrogen levels is asking if they need to normalize their hormone levels before starting finasteride and whether they should postpone dermarolling until they begin finasteride. The user is 21.5 years old.

      community How finasteride or DUT works for me

      in Finasteride/Dutasteride  1 upvotes 2 months ago
      Some users experience side effects from finasteride and switch to alternatives like pyralutamide and a finasteride-minoxidil mix. These alternatives may reduce side effects while helping with hair loss.

      community Can I mix finasteride in just water for topical?

      in Finasteride/Dutasteride  5 upvotes 3 years ago
      The conversation is about whether finasteride can be mixed with just water for a topical solution and if Isopropyl Alcohol and Propylene Glycol are necessary for effectiveness and faster drying. The user is seeking advice on the formulation of topical finasteride.